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A phase I study of panobinostat and ruxolitinib in patients with primary myelofibrosis (PMF) and post-­polycythemia vera/essential thrombocythemia myelofibrosis (post-­PV/ET MF)

Autor: J. Mascarenhas, B.K. Marcellino, M. Lu, M. Kremyanskaya, F. Fabris, L. Sandy, M. Mehrotra, J. Houldsworth, V. Najfeld, S. El Jamal, B. Petersen, E. Moshier, R. Hoffman

Publikováno v: Leukemia Research. 88:106272

Ruxolitinib, a selective JAK1/JAK2 inhibitor, is the current first line therapy for myelofibrosis (MF), which reduces symptomatology and splenomegaly, but does not clearly modify disease course. Panobinostat, a histone deacetylase inhibitor, was show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79c850aae6f60f40c0b1133501bb2e1
https://doi.org/10.1016/j.leukres.2019.106272

Contents, Vol. 64, 1993

Autor: D.W. Cooper, Robin J. Leach, P. Popescu, M.R. Harrison, T. Kranert, H.A. Phillips, C. Collet, J. Xu, M. Yerle, T. Tamura, I. Mísek, N.A. Jenkins, T. Muramatsu, B.O. Bengtsson, E. Capanna, M. Letarte, M. Djabali, R.B. Gaynor, J.R. Testa, J. Zima, R. Wassmuth, T. Bellón, M. Macholán, M. Kawalika, L. Selleri, D.J. Gilbert, T. Ohta, J.C. Mulley, M.J. Reitsma, A. Geurts van Kessel, D. Muhleman, F.J. Otto, E.A. Fon, T. Taguchi, A.D. Thompson, D. Olde Weghuis, V. Najfeld, T. Miyauchi, S. Demczuk, P.N. Tsichlis, D.E. Iles, R.F. Suijkerbuijk, B.-H. Shieh, F.S. Collins, T.W. Glover, G. Levan, H. Lewalski, David Schlessinger, G.A. Evans, M.I. Pigozzi, N.G. Copeland, P. Doi, C.H.M. Mellink, R.S. Sparkes, S. Garagna, G. Thomas, Y. Jinno, B.L. Weber, A. Swaroop, Wl. Flejter, C.A. Redi, K. Klinga Levan, F.M. Kiely, M. Watkins, T. Kajii, N. Andayani, R. Suikerbuijk, A.J. Lusis, E. Fernández-Ruiz, H. Jaafar, G.R. Sutherland, S.L. Gupta, E. Petit, A. Bellacosa, P.A. Lazo, O. Gabriel-Robez, H.M. Kozman, Dennis Drayna, T. Kishino, K. Yoshiura, I. Klisak, T.A. Jones, B.L. De Stavola, Jean-Louis Mandel, L.M. McKenzie, K. Patel, A.L. Hawkins, A.J. Solari, D. Sheer, H. Soejima, J.-Y. Zhou, O. Delattre, R.M. Alfano, H. Hayes, C. Bouniol, G. Viale, Stephen Wood, T. Kaname, A. Kuwano, N. Niikawa, G.P. Chrousos, S. St-Jacques, Y. Matsuda, D. McElligott, C. Lee, N.C. Vamvakopoulos, E. Wang Jabs, K.J. Abel, M.G. Pallavicini, W.H. Moolenaar, G.A. Rouleau, B. Wieringa, J.M. Shipley, Y. Lahbib-Mansais, D.E. Comings, B. Segers, J. Menninger, C.A. Griffin, S.C. Chandrasekharappa, H.-S. Hong, M. Giovannini, Y. Rumpler, H. Burda, Huntington F. Willard, J. Gellin, C. Bernabéu, M.F.G.B. Gebbink

Publikováno v: Cytogenetic and Genome Research. 64:I-IV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8194bd9a5cc2be8ae9de8dd9eb729471
https://doi.org/10.1159/000133569

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Identification of a proviral structure in human breast cancer

Autor: B, Liu, Y, Wang, S M, Melana, I, Pelisson, V, Najfeld, J F, Holland, B G, Pogo

Publikováno v: Cancer research. 61(4)

Involvement of a virus similar to mouse mammary tumor virus (MMTV) in human breast cancer has long been postulated but never demonstrated. We have detected by PCR a 660-bp sequence similar to the env gene of MMTV but not to the known endogenous virus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96aa70f05798088c97d88f33dec97fe9
https://pubmed.ncbi.nlm.nih.gov/11245493