Zobrazeno 1 - 10
of 1 666
pro vyhledávání: '"V, Lombardo"'
Autor:
Veronica Mandelli, Ines Severino, Lisa Eyler, Karen Pierce, Eric Courchesne, Michael V. Lombardo
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Phenotypic heterogeneity in early language, intellectual, motor, and adaptive functioning (LIMA) features are amongst the most striking features that distinguish different types of autistic individuals. Yet the current diagnostic
Externí odkaz:
https://doaj.org/article/76d399662f984017bf9ba76818ba2585
Autor:
Veronica Mandelli, Isotta Landi, Silvia Busti Ceccarelli, Massimo Molteni, Maria Nobile, Alessandro D’Ausilio, Luciano Fadiga, Alessandro Crippa, Michael V. Lombardo
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Motor difficulties are common in many, but not all, autistic individuals. These difficulties can co-occur with other problems, such as delays in language, intellectual, and adaptive functioning. Biological mechanisms underpinning
Externí odkaz:
https://doaj.org/article/2235161e288340c987ccaaad00a9f287
Defluorination of Organofluorine Compounds Using Dehalogenase Enzymes from Delftia acidovorans (D4B)
Autor:
Sanaz Farajollahi, Nina V. Lombardo, Michael D. Crenshaw, Hao-Bo Guo, Megan E. Doherty, Tina R. Davison, Jordan J. Steel, Erin A. Almand, Vanessa A. Varaljay, Chia Suei-Hung, Peter A. Mirau, Rajiv J. Berry, Nancy Kelley-Loughnane, Patrick B. Dennis
Publikováno v:
ACS Omega, Vol 9, Iss 26, Pp 28546-28555 (2024)
Externí odkaz:
https://doaj.org/article/72b19a5b35734eb7bb1d808d21f7e091
Autor:
Kuaikuai Duan, Lisa Eyler, Karen Pierce, Michael V. Lombardo, Michael Datko, Donald J. Hagler, Vani Taluja, Javad Zahiri, Kathleen Campbell, Cynthia Carter Barnes, Steven Arias, Srinivasa Nalabolu, Jaden Troxel, Peng Ji, Eric Courchesne
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Language and social symptoms improve with age in some autistic toddlers, but not in others, and such outcome differences are not clearly predictable from clinical scores alone. Here we aim to identify early-age brain alterations in autism th
Externí odkaz:
https://doaj.org/article/a0c3f4d162474ff2867858421f86f0ad
Autor:
Eric Courchesne, Vani Taluja, Sanaz Nazari, Caitlin M. Aamodt, Karen Pierce, Kuaikuai Duan, Sunny Stophaeros, Linda Lopez, Cynthia Carter Barnes, Jaden Troxel, Kathleen Campbell, Tianyun Wang, Kendra Hoekzema, Evan E. Eichler, Joao V. Nani, Wirla Pontes, Sandra Sanchez Sanchez, Michael V. Lombardo, Janaina S. de Souza, Mirian A. F. Hayashi, Alysson R. Muotri
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Social affective and communication symptoms are central to autism spectrum disorder (ASD), yet their severity differs across toddlers: Some toddlers with ASD display improving abilities across early ages and develop good social an
Externí odkaz:
https://doaj.org/article/428ca825209e4345a0da67a2ab8b0da8
Autor:
Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Joshua D. Bernstock, Shinya Tasaki, Bernard Ng, Chris Gaiteri, Jordan W. Smoller, Tian Ge, Raquel E. Gur, Michael J. Gandal, Aaron F. Alexander-Bloch
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113439- (2023)
Summary: Human brain size changes dynamically through early development, peaks in adolescence, and varies up to 2-fold among adults. However, the molecular genetic underpinnings of interindividual variation in brain size remain unknown. Here, we leve
Externí odkaz:
https://doaj.org/article/64ee1401f7fc44968f6a52b884af8318
Autor:
Yaqiong Xiao, Teresa H. Wen, Lauren Kupis, Lisa T. Eyler, Vani Taluja, Jaden Troxel, Disha Goel, Michael V. Lombardo, Karen Pierce, Eric Courchesne
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Background Social and language abilities are closely intertwined during early typical development. In autism spectrum disorder (ASD), however, deficits in social and language development are early-age core symptoms. We previously reported th
Externí odkaz:
https://doaj.org/article/2c597c894ca948e280f3908996bc93d0
Autor:
Marco Pagani, Noemi Barsotti, Alice Bertero, Stavros Trakoshis, Laura Ulysse, Andrea Locarno, Ieva Miseviciute, Alessia De Felice, Carola Canella, Kaustubh Supekar, Alberto Galbusera, Vinod Menon, Raffaella Tonini, Gustavo Deco, Michael V. Lombardo, Massimo Pasqualetti, Alessandro Gozzi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Autism spectrum disorder (ASD) is characterised by synaptic surplus and atypical functional connectivity. Here, the authors show that synaptic pathology in Tsc2 haploinsufficient mice is associated with autism-like behavior and cortico-striatal hyper
Externí odkaz:
https://doaj.org/article/70359fada3144b60afebb40b9d37244f
Autor:
Malvina N. Skorska, Nancy J. Lobaugh, Michael V. Lombardo, Nina van Bruggen, Sofia Chavez, Lindsey T. Thurston, Madison Aitken, Kenneth J. Zucker, M. Mallar Chakravarty, Meng-Chuan Lai, Doug P. VanderLaan
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Gender dysphoria (GD) is characterized by distress due to an incongruence between experienced gender and sex assigned at birth. Brain functional connectivity in adolescents who experience GD may be associated with experienced gender (vs. assigned sex
Externí odkaz:
https://doaj.org/article/73dc14791c844d19a5f5651a02d0ff86
Autor:
Natasha Bertelsen, Isotta Landi, Richard A. I. Bethlehem, Jakob Seidlitz, Elena Maria Busuoli, Veronica Mandelli, Eleonora Satta, Stavros Trakoshis, Bonnie Auyeung, Prantik Kundu, Eva Loth, Guillaume Dumas, Sarah Baumeister, Christian F. Beckmann, Sven Bölte, Thomas Bourgeron, Tony Charman, Sarah Durston, Christine Ecker, Rosemary J. Holt, Mark H. Johnson, Emily J. H. Jones, Luke Mason, Andreas Meyer-Lindenberg, Carolin Moessnang, Marianne Oldehinkel, Antonio M. Persico, Julian Tillmann, Steve C. R. Williams, Will Spooren, Declan G. M. Murphy, Jan K. Buitelaar, the EU-AIMS LEAP group, Simon Baron-Cohen, Meng-Chuan Lai, Michael V. Lombardo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Natasha Bertelsen et al. develop a computational model to categorize patients with autism spectrum disorder (ASD) into distinct subgroups, based on social-communicative or restricted repetitive behaviors. By integrating publicly available neuroimagin
Externí odkaz:
https://doaj.org/article/c94c4da54e7f411495da1401f7a3c862