Zobrazeno 1 - 10
of 112
pro vyhledávání: '"V, Krutovskikh"'
Autor:
A. Thépot, A. Desanlis, E. Venet, L. Thivillier, V. Justin, A. P. Morel, F. DeFraipont, M. Till, V. Krutovskikh, M. Tommasino, O. Damour, P. Hainaut
Publikováno v:
Journal of Skin Cancer, Vol 2011 (2011)
Epidermal keratinocytes are used as a cell source for autologous and allogenic cell transplant therapy for skin burns. The question addressed here is to determine whether the culture process may induce cellular, molecular, or genetic alterations that
Externí odkaz:
https://doaj.org/article/cf0b63a3a60f4a1aa255b87811a60c67
Autor:
V. Krutovskikh, C. Partensky
Publikováno v:
Cancer/Radiothérapie. 15:716-722
Resume Le cancer est une maladie aux etiologies multiples, aux stades evolutifs extremement varies, qui presente une composante genetique dominante. Un grand nombre de genes qui ont une influence critique pour determiner la croissance cellulaire, la
Autor:
A Guerrier, Rachida Rabilloud, Yvonne Munari-Silem, Pierre Fonlupt, I. Morand, D. Gros, V. Krutovskikh, Christine Audebet, Bernard Rousset
Publikováno v:
Journal of Cell Science. 108:2609-2617
Epithelial cells of the thyroid gland present an uncommon connexin expression pattern, they coexpress connexin32 and connexin43. In the present work, we have analyzed the membrane distribution of these two connexins to determine: (i) whether they co-
Autor:
V, Krutovskikh, C, Partensky
Publikováno v:
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique. 15(8)
Cancer is a multi-etiologic, multistage disease with a prevalent genetic component, which happens when a large number of genes, critical for cell growth, death, differentiation, migration, and metabolic plasticity are altered irreversibly, so as to e
Publikováno v:
International journal of cancer. 86(1)
Gap junctional intercellular communication is often impaired in cancers, and the genes which encode the connexin gap junction proteins are considered to be tumor-suppressor genes. In this study, we analyzed the presence of mutations in the connexin 3
Publikováno v:
Novartis Foundation symposium. 219
Malignant cells usually show altered gap junctional intercellular communication and are often associated with aberrant expression or localization of connexins. Transfection of connexin genes into tumorigenic cells restores normal cell growth, suggest
Autor:
V, Krutovskikh, H, Yamasaki
Publikováno v:
Histology and histopathology. 12(3)
There is a growing body of evidence supporting the etiologic implication of gap junctional intercellular communication disorders in carcinogenesis. Substantial progress has recently been made both in molecular biology of gap junction and in the field
Publikováno v:
Carcinogenesis. 17(8)
Connexins are phylogenetically conserved proteins responsible for gap junctional intercellular communication (GJIC). In tumours, GJIC is frequently disrupted. We have tested the hypothesis that the connexin 37 (Cx37) gene might be mutated in human tu
Publikováno v:
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 18
Publikováno v:
Cancer research. 55(3)
In order to examine whether different connexin gene species exert different degrees of tumor-suppressing activity, we characterized growth characteristics of a gap junction-deficient human cancer cell line, HeLa cells, before and after transfection w