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Antioxidant enzymes in renal cell carcinoma

Autor: Y, Soini, J P, Kallio, P, Hirvikoski, H, Helin, P, Kellokumpu-Lehtinen, T L J, Tammela, M, Peltoniemi, P M, Martikainen, L V, Kinnula

Publikováno v: Histology and histopathology. 21(2)

The aim of the study was to estimate the significance of oxidative/nitrosative damage and expression of antioxidant enzymes in renal cell carcinomas (RCC). For this we investigated immunohistochemically six antioxidant enzymes (AOEs) including MnSOD,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e55a5564f5c6153f8f1c7be2fe126986
https://pubmed.ncbi.nlm.nih.gov/16329040

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Tissue MMP-2 and MMP-9 [corrected] are better prognostic factors than serum MMP-2/TIMP-2--complex or TIMP-1 [corrected] in stage [corrected] I-III lung carcinoma

Autor: S, Hoikkala, P, Pääkkö, Y, Soini, R, Mäkitaro, V, Kinnula, T, Turpeenniemi-Hujanen

Publikováno v: Cancer letters. 236(1)

Matrix metalloproteinases (MMPs) are involved in tumor growth and spreading. Here, we investigated the tumor immunoreactive protein of MMP-2, MMP-9 and TIMP-1 as well as the levels of circulating total TIMP-1 and MMP-2/TIMP-2-complex as prognostic fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f7bbdf3986d1810a3b9dc22dd27bfbb4
https://pubmed.ncbi.nlm.nih.gov/15982804

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Chlamydia pneumoniae infection and inflammation in adults with asthma

Autor: T, Sävykoski, T, Harju, M, Paldanius, H, Kuitunen, A, Bloigu, E, Wahlström, P, Rytilä, V, Kinnula, P, Saikku, M, Leinonen

Publikováno v: Respiration; international review of thoracic diseases. 71(2)

Chlamydia pneumoniae infection and immune response to the C. pneumoniae heat shock protein 60 (CpHsp60) have been suggested to be associated with asthma.To study whether a slightly elevated C-reactive protein (CRP) level as a marker of low-grade syst

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2613f95a68613a49dbb95059d35ea746
https://pubmed.ncbi.nlm.nih.gov/15031565

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MnSOD expression is less frequent in tumour cells of invasive breast carcinomas than in in situ carcinomas or non-neoplastic breast epithelial cells

Autor: Y, Soini, M, Vakkala, K, Kahlos, P, Pääkkö, V, Kinnula

Publikováno v: The Journal of pathology. 195(2)

Manganese superoxide dismutase (MnSOD) is an antioxidant enzyme capable of neutralizing superoxide anion molecules. In previous studies it has been suggested to suppress both tumour proliferation and apoptosis. This study investigated 65 invasive, 50

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f0df0bdd3f3d6c37d8c579c88409ebfb
https://pubmed.ncbi.nlm.nih.gov/11592093

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Endothelial nitric oxide synthase is strongly expressed in malignant mesothelioma but does not associate with vascular density or the expression of VEGF, FLK1 or FLT1

Autor: Y, Soini, A, Puhakka, K, Kahlos, M, Säily, P, Pääkkö, P, Koistinen, V, Kinnula

Publikováno v: Histopathology. 39(2)

To investigate endothelial nitric oxide synthase (eNOS) expression in malignant mesothelioma and its association with expression of vascular endothelial growth factor (VEGF), its receptors FLK1 and FLT1, and vascular density.eNOS, VEGF, FLK1 and FLT1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4054ce0974f15683e0eed76f9adae669
https://pubmed.ncbi.nlm.nih.gov/11493335

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Inducible nitric oxide synthase expression, apoptosis, and angiogenesis in in situ and invasive breast carcinomas

Autor: M, Vakkala, K, Kahlos, E, Lakari, P, Pääkkö, V, Kinnula, Y, Soini

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)

In this investigation, we studied the expression of inducible nitric oxide synthase (iNOS) and its association to apoptosis and angiogenesis in 43 in situ and 68 invasive breast carcinomas. Its expression was studied immunohistochemically using a pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::aeafed019ae72c2832bd9f631a2fe4c3
https://pubmed.ncbi.nlm.nih.gov/10873093

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Induction of mitochondrial manganese superoxide dismutase confers resistance to apoptosis in acute myeloblastic leukaemia cells exposed to etoposide

Autor: P, Mäntymaa, T, Siitonen, T, Guttorm, M, Säily, V, Kinnula, E R, Savolainen, P, Koistinen

Publikováno v: British journal of haematology. 108(3)

We investigated the possible roles of mitochondrial manganese superoxide dismutase (MnSOD) and bcl-2 in etoposide-induced cell death in acute myeloblastic leukaemia (AML) using two subclones of the OCI/AML-2 cell line, the etoposide-sensitive (ES) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e3661d80150cef9bd5d81ae052c1433e
https://pubmed.ncbi.nlm.nih.gov/10759716

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Apoptosis and expression of apoptosis regulating proteins bcl-2, mcl-1, bcl-X, and bax in malignant mesothelioma

Autor: Y, Soini, V, Kinnula, R, Kaarteenaho-Wiik, E, Kurttila, K, Linnainmaa, P, Pääkkö

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 5(11)

We investigated apoptosis and the expression of bcl-2, mcl-1, bcl-X, and bax in histological sections from 35 malignant mesotheliomas and 21 metastatic adenocarcinomas. Moreover, the expression of bcl-2, mcl-1, bcl-X, and bax were assessed by Western

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fde91a2f62eabbbd4a14877a45375c29
https://pubmed.ncbi.nlm.nih.gov/10589765

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