Výsledky vyhledávání - "V, Ganga Reddy"

Synthesis of Gold(I) Complexes Containing Cinnamide: In Vitro Evaluation of Anticancer Activity in 2D and 3D Spheroidal Models of Melanoma and In Vivo Angiogenesis

Autor: T. Srinivasa Reddy, Steven H. Privér, Donald Wlodkowic, Shweta Mishra, Suresh K. Bhargava, Nedaossadat Mirzadeh, Yutao Bai, V. Ganga Reddy

Publikováno v: Inorganic Chemistry. 58:5988-5999

A series of alkynylgold(I) phosphine complexes containing methoxy-substituted cinnamide moieties (3a-3c and 4a-4c) have been synthesized and characterized. All of the synthesized complexes were evaluated for their cytotoxicity against three human can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd168313fb1a123da87d649fa34c2e2f
https://doi.org/10.1021/acs.inorgchem.9b00281

Zobrazit plný text záznamu

Synthesis of benzo[ d ]imidazo[2,1- b ]thiazole-chalcone conjugates as microtubule targeting and apoptosis inducing agents

Autor: Sunitha Rani Routhu, M. Sampath Kumar Halmuthur, V. Ganga Reddy, Abdullah Alarifi, Srinivasa Reddy Bonam, Ravikumar Akunuri, V. Lakshma Nayak, Faria Sultana, Ahmed Kamal

Publikováno v: Bioorganic Chemistry. 76:1-12

A series of benzo[d]imidazo[2,1-b]thiazole-chalcone conjugates (5a-aa) were designed, synthesized and evaluated for their cytotoxic potency against a panel of human cancer cell lines like lung (A-549), breast (MDA MB-231), prostrate (DU-145) and colo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aad566082908ea1cb47267f7003d6db
https://doi.org/10.1016/j.bioorg.2017.10.019

Zobrazit plný text záznamu

4 β -amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer

Autor: Ahmed Kamal, V. Lakshma Nayak, V.G.M. Naidu, T. Srinivasa Reddy, Ravikumar Akunuri, Srinivasa Reddy Bonam, Pabbaraja Srihari, V. Ganga Reddy, Suresh K. Bhargava, H.M. Sampath Kumar

Publikováno v: European Journal of Medicinal Chemistry. 144:595-611

Topoisomerases (topo-I and topo-II) have occupied a significant role in DNA replication, transcription, and are a promising set of antitumor targets. In the present approach, a series of new 4 beta-amidotriazole linked podophyllotoxin derivatives (10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4d4499946700250ba593ae8da655810
https://doi.org/10.1016/j.ejmech.2017.12.050

Zobrazit plný text záznamu

Design, synthesis and biological evaluation of 1, 4-dihydro indeno[1,2- c ] pyrazole linked oxindole analogues as potential anticancer agents targeting tubulin and inducing p53 dependent apoptosis

Autor: Manika Pal-Bhadra, Koteswara Rao Garikapati, Mohd Adil Shareef, Irfan Khan, Abdul Rahim, Ahmed Kamal, Anver Basha Shaik, V. Ganga Reddy, Venkata Krishna Kanth Makani, C. Ganesh Kumar

Publikováno v: European Journal of Medicinal Chemistry. 144:104-115

A series of 1, 4-dihydroindeno-[1,2-c] pyrazole linked oxindole conjugates have been synthesized by using Knoevenagel condensation method and further evaluated for their antiproliferative activity against HeLa, A549 and MDA-MB-231 human cancer cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7431a7454990cbed88510acc5af0c549
https://doi.org/10.1016/j.ejmech.2017.12.010

Zobrazit plný text záznamu

Annulation of 4-Hydroxypyrones and α-Keto Vinyl Azides; A Regiospecific Approach towards the Synthesis of Furo[3, 2-c]Pyrone Scaffolds under Catalyst Free Condition

Autor: Ahmed Kamal, Namballa Hari Krishna, Abdullah Alarifi, Jagadeesh Babu Nanubolu, V. Ganga Reddy, Budaganaboyina Prasad, N. V. Subba Reddy

Publikováno v: ChemistrySelect. 2:8122-8126

A mild and efficient strategy for the construction of furo[3, 2-c]pyrones via an annulation of α-keto vinyl azides and 4-hydroxypyrones under catalyst free condition has been described. Several furo[3, 2-c]pyrone scaffolds were synthesized from read

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::955401ce8bbbb0b918ff06014ecec813
https://doi.org/10.1002/slct.201701980

Zobrazit plný text záznamu

Design, synthesis and biological evaluation of N -((1-benzyl-1 H -1,2,3-triazol-4-yl)methyl)-1,3-diphenyl-1 H -pyrazole-4-carboxamides as CDK1/Cdc2 inhibitors

Autor: A. Ravikumar, V. Ganga Reddy, Adiyala Praveen Reddy, V. Lakshma Nayak, Shaik Taj, Budaganaboyina Prasad, Ahmed Kamal, T. Srinivasa Reddy

Publikováno v: European Journal of Medicinal Chemistry. 122:164-177

A series of new (N-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide derivatives (8–35) were designed, synthesized and evaluated as CDK1/Cdc2 inhibitors. Biological evaluation assays indicated that compounds 16 and 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::627d73b52e40394684157b41bb159ffe
https://doi.org/10.1016/j.ejmech.2016.06.011

Zobrazit plný text záznamu

Synthesis of ( Z )-1-(1,3-diphenyl-1 H -pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents

Autor: V. Ganga Reddy, Ravi Shukla, Ahmed Kamal, T. Srinivasa Reddy, Vipul Bansal, Hitesh Kulhari

Publikováno v: European Journal of Medicinal Chemistry. 117:157-166

A series of (Z)-1-(1,3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino)prop-2-en-1-one derivatives were synthesized and characterized by (1)H and (13)C NMR, ESI-MS and HRMS. All the synthesized compounds were evaluated for their anticancer activity against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ba0fd5fd4f6c37218e38ff44ffc11
https://doi.org/10.1016/j.ejmech.2016.03.051

Zobrazit plný text záznamu

An evaluation of the CYP2D6 and CYP3A4 inhibition potential of metoprolol metabolites and their contribution to drug-drug and drug-herb interaction by LC-ESI/MS/MS

Autor: Abhay T. Sangamwar, Roshan M. Borkar, Sanjay K. Banerjee, R. Srinivas, V. Ganga Reddy, Ahmed Kamal, Murali Mohan Bhandi, Ajay P. Dubey, Prashanth Komirishetty, Prajwal P. Nandekar

Publikováno v: Biomedical Chromatography. 30:1556-1572

The aim of the present study was to evaluate the contribution of metabolites to drug-drug interaction and drug-herb interaction using the inhibition of CYP2D6 and CYP3A4 by metoprolol (MET) and its metabolites. The peak concentrations of unbound plas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0da94130bf3b991231ec0d687f87c437
https://doi.org/10.1002/bmc.3721

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání