Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial

Autor: Erin A Bohula, Benjamin M Scirica, Silvio E Inzucchi, Darren K McGuire, Anthony C Keech, Steven R Smith, Estella Kanevsky, Sabina A Murphy, Lawrence A Leiter, Jamie P Dwyer, Ramon Corbalan, Christian Hamm, Lee Kaplan, Jose Carlos Nicolau, Ton Oude Ophuis, Kausik K Ray, Mikhail Ruda, Jindrich Spinar, Tushar Patel, Wenfeng Miao, Carlos Perdomo, Bruce Francis, Shobha Dhadda, Marc P Bonaca, Christian T Ruff, Marc S Sabatine, Stephen D Wiviott, Silvio Inzucchi, Anthony Keech, Andrew Satlin, Conville Brown, Andrzej Budaj, Jamie Dwyer, Armando Garcia-Castillo, Milan Gupta, Kauski Ray, Neil Weissman, Harvey D White, J Amerena, M Arstall, D Colquhoun, R Jayasinghe, A Lee, R Lehman, R Moses, J Proietto, P Purnell, J Waites, P Blombery, D Cross, M Worthley, M d'Emden, J Selvanayagam, RE Oqueli, A Whelan, P Garrahy, F de Looze, D Ninio, J Horowitz, M William, M Suranyi, G Wittert, M Le May, AS Pandey, S Vizel, R Labonte, Y Beaudry, C Fortin, A Bell, S Kouz, É St-Amour, I Bata, F St Maurice, R Chehayeb, C Constance, G Wong, A Hess, J Liutkus, P Poirier, I Teitelbaum, J Berlingieri, J Cha, M Hartleib, M Heffernan, D Twum-Barima, V Pandith, R Aronson, R Goldenberg, B Ajala, A Jain, S Ross, H Bajaj, H Khandwala, Z Yared, N Gupta, J Bédard, S Wharton, F Blouin, D Savard, D Shukla, J Cobos, G Godoy, L Perez, C Pincetti, V Saavedra Guajardo, P Varleta, C Conejeros, F Lanas, E Bayram Llamas, E Cardona Muñoz, R Garcia, J Garza Ruiz, G Llamas Esperon, E Lopez Rosas, G Melendez Mier, G Ramos, H Hart, D Scott, I Ternouth, J Benatar, J Elliott, R Cutfield, P Manning, M Williams, K Ferrier, R Scott, S Wilson, R Leikis, BK Nirmalaraj, E Krzyżagórska, P Miękus, M Bronisz, E Mirek-Bryniarska, K Łanda, A Stasiewski, T Żechowicz, D Zytkiewicz-Jaruga, J Korecki, M Ogórek, L Pawłowicz, M Piepiorka, J Skierkowska, A Stankiewicz, E Szyprowska, R Witek, A Bochenek, P Kończakowski, Ł Wojnowski, M Wujkowski, K Cymerman, R Korzeniak, P Mąder, B Mikłaszewicz, P Stachlewski, A Goch, W Pomiećko, M Skórski, L Romanowski, K Jusiak, E Laskowska-Derlaga, R Bijata-Bronisz, J Kaźmierczak, R Goldberg, D Henderson, E Korban, K Rohr, E Claxton, R Weiss, D Angiolillo, F Boccalandro, K Chu, E Thorn, P Randhawa, N Singh, G Bittar, T Guarnieri, S Saeed, S Sharma, M Shepard, W French, P Desai, R Bernstein, W Rogers, R Singal, R Schneider, J Shanes, S Ong, J Condit, S Donahoe, D Brill, D Einhorn, R Ebrahimi, A Labroo, R Graf, J Scott, J Hoekstra, P Jetty, G Luckasen, P O'Donnell, W Gonte, D Pomposini, M Quadrel, M Koren, D Schlager, E Schramm, D Singal, S Lupovitch, A Soni, P Seigel, J Roberts, J Soufer, S Reza, E Quinlan, T Moretto, B First, M Khan, S Chilka, H Colfer, A Teklinski, K Wallace-Wilding, H Ellison, D Muse, S Aronoff, A Higgins, S Patel, V Elinoff, A Karim, V Awasty, R Chuang, H Roseman, P Dugano-Daphnis, M Albert, K Sheikh, H Bays, S Kaster, M Goldstein, D Rubino, G Calatayud, H Snyder, T Williams, K Hershon, M Hagan, S Isserman, B Kahn, J Anderson, MP Gimness, A Raisinghani, M Christina, M Raikhel, E Gillespie, E Portnay, M Heiman, M Qureshi, J Lee, R Blonder, F Cucher, G Miller, D Kotlaba, G Cornett, J Beavins, C Augenbraun, S Reinhardt, A Bartkowiak, A Salacata, T Blevins, S Benjamin, J Diener, W George, B Barker, R Richwine, D Baldari, A Alfieri, A Barreto, L Zhang, R Shah, E Hendrix, V Subramaniyam, S Hurley, M Lillestol, M O'Donoghue, S Shayani, E Ryan, R Call, L Zemel, A Chang, A Kivitz, B Freyne, V Bland, K Shore, E Mostel, E Uzoaga, N Andrawis, N Gabra, A Ghitis, K Sabatino, D Browder, S Varma, S Smith, R Fink, GR Aycock, WD Doty, T Alfonso, S Eshaghian, R Karlsberg, S Zarich, C Landau, M McKenzie, R Krause, W Davis, T Haddad, S Voyce, C Alford, J LeDoux, D O'Dea, J Park, V Aroda, A Getaneh, B Graham, R Bhagwat, D Korn, G Ruoff, A Wiseman, I Lieber, J Fialkow, JM Gonzalez-Campoy, C Bayron, B Bertolet, J Lash, C Gerrish, D Robertson, J Rosenfeld, M Seidner, J Agaiby, J Silverfield, D Sugimoto, B Lubin, M Alhaddad, H Lui, G Lakin, S Chokshi, D Donovan, W Felten, S Minton, C Kimmelstiel, J Kuvin, C Still, W Byars, J Talano, V Desai, AJ Bradley, S Baker, M Chane, A Mercado, S Baron, B Harris, N Mayer, M Concha, K Carr, L Chaykin, J Willis, A Clay, E Fenstad, J Furda, P Peterson, M Chang, L Aronne, D Jones, R Prashad, M Benson, R Stegemoller, K Longshaw, J Saleh, W Jennings, R Detweiler, D Viswanath, R Patel, S Lederman, D Weinstein, R Korabathina, V Singh, J Rosen, R Estevez, P Levin, R McNeill, V Kalen, J Reed, R Ashley, L Herman, Y Tsai, D Kayne, A White, I Hussain, L Tami, K Cohen, J Robinson, D Fuchs-Ertman, G Platt, L Belardo, R Reddy, C Rosendorff, F Saba, S Powell, K Anderson, M Abidi, S Rezkalla, A Paraschos, J Wilson, M Moursi, A Shah, V Nadar, L Stonesifer, M Bialow, K Cannon, W Ellison, M Stedman, J Brown, W Harper, KJ Lucas, M DiGiovanna, H Rodbard, M Biscoveanu, C Davis, J Hall, R Littlefield, T Gorman, D Kereiakes, FM Chang, H Tatu, D Cheung, J Kaine, T Knutson, T Logemann, G Pueblitz, J Bianco, B Henson, M Neustel, M Gelernt, W Nelson, K Moriarty, G Lefebvre, K Maw, L Rink, P Behn, H Studdard, G Argoud, T O'Connor, P Krichmar, G Raad, J Pereles-Ortiz, C Sorli, A Cohen, K Pettis, B Cavanaugh, C Phillips, J Wahlen, D Radin, J Rider, E Kosinski, W Leimbach, A Odhav, J Hakas, A Tan, M Howell, D Wombolt, N Fishman, P Shah, P Wylie, C Arauz-Pacheco, A Cavale, A George, R Kroll, J Krantzler, N Tahirkheli, M Jabro, M Newell, P Mullen, N Gencheff, J Meli, K Vora, L Kotek, K Pyzdrowski, H Paez, J Moran, A Tannenbaum, K Deck, R Busch, L Levinson, M Azizad, J Whitaker, B Fox, C Huffman, M Ashraf, J Diogo, R Kushner, J Tallet, V Channamsetty, D Suh, M Atieh, J Navas, V Young, S Shaw, I Dor, B Duffy, P Rubin, D Lewis, W Kaye, R Benton, J Burbano, D Hotchkiss, A Magno, A Alberton, J Collins, O Alvarado, M Stich, S Mahal, J Liu, M Hong, J Dy, B Block, J Lamantia, J Pritchard, M Davis, S Srivastava, S Bilazarian, R Rosario, M McCartney, V Blumberg, R Rajan, E Martin, S Wright, C Brinson, J Johnston, M Graves, M Dominguez, W McKenzie, R Abadier, C Tran, R Castello, E Morawski, J White, F Morris, A Perez, P Trueba, M Sanchez, J Andersen, R Kastelic, J Khan, H Rodriguez, W Izquierdo, A Matias, L Essandoh, C Ince

Publikováno v: Lancet (London, England). 392(10161)

BACKGROUND: There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has been shown to facilitate sustained weight loss in obese or overweight patients. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a4e189e200fa6beb5d4585cfb676ca
https://pubmed.ncbi.nlm.nih.gov/30740430

Lipid-modifying efficacy and tolerability of extended-release niacin/laropiprant in patients with primary hypercholesterolaemia or mixed dyslipidaemia

Autor: John F. Paolini, Abigaile Betteridge, Anders G. Olsson, Robert Reyes, A. Elis, C. McCrary Sisk, Qinfen Yu, Harold E. Bays, Waheeda Sirah, Olga M. Kuznetsova, Richard C. Pasternak, Darbie Maccubbin, V. Elinoff, Yale B. Mitchel

Publikováno v: International Journal of Clinical Practice. 62:1959-1970

Summary Background: Improving lipids beyond low-density lipoprotein cholesterol (LDL-C) lowering with statin monotherapy may further reduce cardiovascular risk. Niacin has complementary lipid-modifying efficacy to statins and cardiovascular benefit,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b45ac1704417c2a1a82326009d07d8b
https://doi.org/10.1111/j.1742-1241.2008.01938.x

Tolterodine extended release improves patient-reported outcomes in overactive bladder: results from the IMPACT trial

Autor: N. Eyland, Dale B. Glasser, V. Elinoff, Richard G. Roberts, Martin Carlsson, Tamara Bavendam

Publikováno v: International Journal of Clinical Practice. 60:752-758

Summary We evaluated the effect of tolterodine extended release (ER) on patient- and clinician-reported outcomes in a primary care setting. Patients had overactive bladder (OAB) symptoms for ≥3 months and were at least moderately bothered by their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55de7afe589623bfe220277745578145
https://doi.org/10.1111/j.1742-1241.2006.00987.x

Validation of a 3-item OAB awareness tool

Autor: K S, Coyne, M K, Margolis, T, Bavendam, R, Roberts, V, Elinoff

Publikováno v: International journal of clinical practice. 65(2)

The purpose of this study was to validate a short awareness tool to assist patients in identifying if they have bothersome overactive bladder (OAB) symptoms.This secondary analysis study utilised data from a cross-sectional study of adult patients pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ed1130cb7332b35eff9e7ab197283e5
https://pubmed.ncbi.nlm.nih.gov/21235701

Relationships between improvements in symptoms and patient assessments of bladder condition, symptom bother and health-related quality of life in patients with overactive bladder treated with tolterodine

Autor: K S, Coyne, V, Elinoff, D A, Gordon, D Y, Deng, M, Brodsky, D B, Glasser, Z, Jumadilova, M, Carlsson

Publikováno v: International journal of clinical practice. 62(6)

Relationships were evaluated between treatment-related improvements in overactive bladder (OAB) symptoms as recorded in bladder diaries and patient-reported symptom bother, bladder-related problems and health-related quality of life (HRQL).A post hoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a669e68bae2292fafcf74de7534e7289
https://pubmed.ncbi.nlm.nih.gov/18479285