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Akademický článek

Cost-effectiveness of pessary therapy versus surgery for symptomatic pelvic organ prolapse: an economic evaluation alongside a randomised non-inferiority controlled trial

Publikováno v: BMJ Open, Vol 14, Iss 5 (2024)

Objective To evaluate the cost-effectiveness of pessary therapy as an initial treatment option compared with surgery for moderate to severe pelvic organ prolapse (POP) symptoms in secondary care from a healthcare and a societal perspective.Design Eco

Externí odkaz: https://doaj.org/article/e4be20408687422c8ae4f5234762c799

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Akademický článek

Adjuvant dendritic cell-based immunotherapy after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in patients with malignant peritoneal mesothelioma: a phase II clinical trial

Autor: Nadine L de Boer, Job P van Kooten, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Marcella Willemsen, Michelle V Dietz, Katrien L A Quintelier, Madelief Vink, Yvan Saeys, Sofie Van Gassen

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 8 (2023)

Background Malignant peritoneal mesothelioma (MPM) is an aggressive malignancy with a poor prognosis. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival outcomes, but recurrence rates remain high. Dend

Externí odkaz: https://doaj.org/article/4969d9c96188451cb2fee28a466fa4a5

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Akademický článek

Coordination of metal center biogenesis in human cytochrome c oxidase

Autor: Eva Nývltová, Jonathan V. Dietz, Javier Seravalli, Oleh Khalimonchuk, Antoni Barrientos

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)

Mitochondrial cytochrome c oxidase is a heme aa3-copper oxygen reductase. Here, authors report that metal center-specific metallochaperones form dynamic assemblies to control heme a biosynthesis and coordinate copper transfer to the copper sites.

Externí odkaz: https://doaj.org/article/43d49fed77534d76827f1f25f3c7eb73

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Akademický článek

Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase

Autor: Jonathan V. Dietz, Mathilda M. Willoughby, Robert B. Piel, III, Teresa A. Ross, Iryna Bohovych, Hannah G. Addis, Jennifer L. Fox, William N. Lanzilotta, Harry A. Dailey, James A. Wohlschlegel, Amit R. Reddi, Amy E. Medlock, Oleh Khalimonchuk

Publikováno v: Redox Biology, Vol 46, Iss , Pp 102125- (2021)

Heme is an essential cofactor required for a plethora of cellular processes in eukaryotes. In metazoans the heme biosynthetic pathway is typically partitioned between the cytosol and mitochondria, with the first and final steps taking place in the mi

Externí odkaz: https://doaj.org/article/b5b8982ff5e84ce3a38023b6ecfea0bd

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Akademický článek

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Akademický článek

Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond

Autor: Jonathan V. Dietz, Jennifer L. Fox, Oleh Khalimonchuk

Publikováno v: Cells, Vol 10, Iss 9, p 2198 (2021)

Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support e

Externí odkaz: https://doaj.org/article/b785e6f999f44efb903d5035a2d466cc

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Laparoscopic sacrocolpopexy versus vaginal sacrospinous fixation for vaginal vault prolapse: a randomised controlled trial and prospective cohort (SALTO-2 trial)

Autor: A. M. J. van Oudheusden, M. N. van IJsselmuiden, L. F. Menge, A.‐L. W. M. Coolen, J. Veen, H. W. F. van Eijndhoven, V. Dietz, K. B. Kluivers, W. A. Spaans, A. Vollebregt, G. van de Pol, C. M. Radder, J. M. van der Ploeg, S. M. J. van Kuijk, M. Y. Bongers

Publikováno v: Bjog-an International Journal of Obstetrics and Gynaecology. Wiley

Objective: To determine whether laparoscopic sacrocolpopexy (LSC) or vaginal sacrospinous fixation (VSF) is the most optimal surgical treatment in patients with POP-Q stage =2 vaginal vault prolapse (VVP).Design: Multicentre randomised controlled tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::504d3047b93ce9a411409ac5bcf84d23
https://cris.maastrichtuniversity.nl/en/publications/fd7b0db4-2fa9-4612-8647-1b610ed1dcc6

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Treatment and Survival Outcomes for Patients with Colorectal Peritoneal Metastases Deemed Ineligible for Cytoreductive Surgery (CRS) with Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Results of a Retrospective Study

Autor: Michelle V. Dietz, Merijn J. Ziekman, Job P. van Kooten, Alexandra R. M. Brandt-Kerkhof, Esther van Meerten, Cornelis Verhoef, Eva V. E. Madsen

Publikováno v: Annals of Surgical Oncology, 30(4), 2048-2056. Springer New York

Background: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment option for selected patients with colorectal peritoneal metastases (PM). This report provides an overview of treatment and survival outcomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f8ae07aa4ca5b4a745dcf0f6559408
https://pure.eur.nl/en/publications/81be2733-09c6-43d4-9b16-34636d0a5d39

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