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Autor:
Christiane Gauville, Fabien Calvo, V. Closson, G Linares, B. Olofsson, P. De Cremoux, Armand Tavitian
Publikováno v:
International Journal of Cancer. 59:408-415
The mRNA levels of the ras-related human rhoA, rhoB and rhoC genes were studied in human breast-cancer cell lines (HBCal), and in normal and immortalized mammary epithelial cells (HMEC) by Northern blot analysis and in situ hybridization. In contrast
Autor:
L T, Krebs, Y, Xue, C R, Norton, J R, Shutter, M, Maguire, J P, Sundberg, D, Gallahan, V, Closson, J, Kitajewski, R, Callahan, G H, Smith, K L, Stark, T, Gridley
Publikováno v:
Genesdevelopment. 14(11)
The Notch gene family encodes large transmembrane receptors that are components of an evolutionarily conserved intercellular signaling mechanism. To assess the role of the Notch4 gene, we generated Notch4-deficient mice by gene targeting. Embryos hom
Publikováno v:
The Journal of biological chemistry. 271(48)
RhoB is a small GTP-binding protein highly homologous to the RhoA protein. While RhoA is known to regulate the assembly of focal adhesions and stress fibers in response to growth factors, the function of RhoB remains unknown. We have reported that th
Publikováno v:
Oncogene. 10(10)
The immediate-early gene rhoB codes for a small GTP-binding protein highly homologous to the RhoA protein. While RhoA is known to regulate the assembly of focal adhesions and stress fibers in response to growth factors, the function of RhoB remains u
Publikováno v:
The Canadian journal of hospital pharmacy. 48(2)
Granulocyte Colony-Stimulating Factor or G-CSF (NEUPOGEN) was approved for use in France in November 1991 for prevention of chemotherapy-induced neutropenia. This retrospective study was conducted at Saint-Louis Hospital, Paris, France, from November
Autor:
V. Closson, Jean-Pierre Droz, Stéphane Culine, Michel Marty, Nicole Honoré, B. Olofsson, Armand Tavitian, Jean-Marc Extra
Publikováno v:
European journal of cancer (Oxford, England : 1990). (5)
ras oncoproteins and ras-related proteins constitute a large family of the small GTP-binding protein family. The rab branch of the ras superfamily is involved in the intracellular transport along the secretory and endocytic pathway in eukaryotic cell
Publikováno v:
Nouvelle revue francaise d'hematologie. 35(1)
The Rab branch of the Ras-related guanine nucleotide (GTP/GDP)-binding proteins currently includes at least thirty related members which are involved in the intracellular vesicular transport along the secretory and endocytic pathways in eukaryotic ce
Autor:
Karl Zabjek, V. Closson, William H. Gage, S.W. Hill, Brian E. Maki, William E. McIlroy, Cynthia J. Danells
Publikováno v:
Gait & Posture. 21:S136
Publikováno v:
médecine/sciences. 11:1551
Les outils de la biologie cellulaire ont permis de dissequer les voies de transmission du signal passant par les proteines Rho (en particulier les proteines Rho, Rac et Cdc42). Ce sont des membres de la superfamille des GTPases Ras, impliquees dans l