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Akademický článek

Dendritic Cell-Derived Artificial Microvesicles Inhibit RLS40 Lymphosarcoma Growth in Mice via Stimulation of Th1/Th17 Immune Response

Autor: Oleg V. Markov, Aleksandra V. Sen’kova, Islam S. Mohamed, Elena V. Shmendel, Mikhail A. Maslov, Anastasiya L. Oshchepkova, Evgeniy V. Brenner, Nadezhda L. Mironova, Marina A. Zenkova

Publikováno v: Pharmaceutics, Vol 14, Iss 11, p 2542 (2022)

Cell-free antitumor vaccines represent a promising approach to immunotherapy of cancer. Here, we compare the antitumor potential of cell-free vaccines based on microvesicles derived from dendritic cells (DCs) with DC- and cationic-liposome-based vacc

Externí odkaz: https://doaj.org/article/eb3ad4ee0c254b07bea709de01437fb6

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Akademický článek

Core genes involved in the regulation of acute lung injury and their association with COVID-19 and tumor progression: A bioinformatics and experimental study.

Autor: Aleksandra V Sen'kova, Innokenty A Savin, Evgenyi V Brenner, Marina A Zenkova, Andrey V Markov

Publikováno v: PLoS ONE, Vol 16, Iss 11, p e0260450 (2021)

Acute lung injury (ALI) is a specific form of lung damage caused by different infectious and non-infectious agents, including SARS-CoV-2, leading to severe respiratory and systemic inflammation. To gain deeper insight into the molecular mechanisms be

Externí odkaz: https://doaj.org/article/71af97a7589f4458a857b23cfd978f2c

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Age effects on radiation response: summary of a recent symposium and future perspectives

Autor: Mark P. Little, Alina V. Brenner, Eric J. Grant, Hiromi Sugiyama, Dale L. Preston, Ritsu Sakata, John Cologne, Raquel Velazquez-Kronen, Mai Utada, Kiyohiko Mabuchi, Kotaro Ozasa, John D. Olson, Gregory O. Dugan, Simonetta Pazzaglia, J. Mark Cline, Kimberly E. Applegate

Publikováno v: International journal of radiation biology.

One of the principal uncertainties when estimating population risk of late effects from epidemiological data is that few radiation-exposed cohorts have been followed up to extinction. Therefore, the relative risk model has often been used to estimate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d35c42484162e0055235b758421c0a
https://pubmed.ncbi.nlm.nih.gov/35394411

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The Effect of Prostate-Specific Antigen (PSA) Test on Radiation Risk Estimate for Prostate Cancer Incidence among Atomic-Bomb Survivors

Autor: Mai Utada, Alina V. Brenner, Dale L. Preston, Michiko Yamada, Eric J. Grant, Hiromi Sugiyama, Ritsu Sakata, Elizabeth K. Cahoon, Kotaro Ozasa, Kiyohiko Mabuchi

Publikováno v: Radiation Research.

Following our previous report on the radiation dose-response for prostate cancer incidence rates in the Life Span Study (LSS) cohort of atomic bomb survivors, we re-evaluated the radiation-related risk adjusting for differences in baseline cancer inc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db2d1b9358ef7f65d0a6636af07b515f
https://doi.org/10.1667/rade-22-00089.1

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Impact of uncertainties in exposure assessment on thyroid cancer risk among cleanup workers in Ukraine exposed due to the Chornobyl accident

Autor: Mark P. Little, Elizabeth K. Cahoon, Natalia Gudzenko, Kiyohiko Mabuchi, Vladimir Drozdovitch, Maureen Hatch, Alina V. Brenner, Vibha Vij, Konstantin Chizhov, Elena Bakhanova, Natalia Trotsyuk, Victor Kryuchkov, Ivan Golovanov, Vadim Chumak, Dimitry Bazyka

Publikováno v: European Journal of Epidemiology. 37:837-847

A large excess risk of thyroid cancer was observed among Belarusian/Russian/Baltic Chornobyl cleanup workers. A more recent study of Ukraine cleanup workers found more modest excess risks of thyroid cancer. Dose errors in this data are substantial, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d00ed000326cdfd24eb4706bc96b84
https://doi.org/10.1007/s10654-022-00850-z

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Publisher Correction: Impact of uncertainties in exposure assessment on thyroid cancer risk among cleanup workers in Ukraine exposed due to the Chornobyl accident

Publikováno v: European Journal of Epidemiology. 37:881-883

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96026e3c054c0b2c08a532f44216cc15
https://doi.org/10.1007/s10654-022-00882-5

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Cervicovaginal-Microbiome Analysis by 16S Sequencing and Real-Time PCR in Patients from Novosibirsk (Russia) with Cervical Lesions and Several Years after Cancer Treatment

Autor: Mikhail K. Ivanov, Evgeny V. Brenner, Anastasia A. Hodkevich, Victoria V. Dzyubenko, Sergey E. Krasilnikov, Alphiya S. Mansurova, Irina E. Vakhturova, Eduard F. Agletdinov, Anastasia O. Shumeikina, Alyona L. Chernyshova, Sergei E. Titov

Publikováno v: Diagnostics; Volume 13; Issue 1; Pages: 140

Disturbed cervicovaginal-microbiome (CVM) structure promotes human papillomavirus (HPV) persistence and reflects risks of cervical lesions and cancer onset and recurrence. Therefore, microbiomic biomarkers may be useful for cervical disease screening

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6ddc9ccd3e7fb690c118f67016ba42e
https://pubmed.ncbi.nlm.nih.gov/36611432

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Akademický článek

Alteration of the exDNA profile in blood serum of LLC-bearing mice under the decrease of tumour invasion potential by bovine pancreatic DNase I treatment.

Autor: Ludmila A Alekseeva, Nadezhda L Mironova, Evgenyi V Brenner, Alexander M Kurilshikov, Olga A Patutina, Marina A Zenkova

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171988 (2017)

Taking into account recently obtained data indicating the participation of circulating extracellular DNA (exDNA) in tumorigenesis, enzymes with deoxyribonucleic activity have again been considered as potential antitumour and antimetastatic drugs. Pre

Externí odkaz: https://doaj.org/article/2dcbbebd1fe042e0af3255dbcedff788

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