Výsledky vyhledávání - "V, Brankovan"

Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogs

Autor: V. Brankovan, Joanne J. Bronson, Kuo Long Yu, A K Patick, R. Datema, Hyekyung Yang, M. Alam, J. C. Martin, Michael J. M. Hitchcock

Publikováno v: Journal of Medicinal Chemistry. 36:2726-2738

A series of 2'-substituted derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and evaluated in vitro for anti-human immunodeficiency virus (HIV) activity in the XTT assay and for anti-herpes activity in the plaque red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1d5da2103acb95c39813802e6158cc8
https://doi.org/10.1021/jm00071a003

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Anti-HIV Activity of Several 2′-Fluoro-Containing Pyrimidine Nucleosides

Autor: Muzammil M. Mansuri, Sterzycki Roman Z, J. C. Martin, Ismail Ghazzouli, V. Brankovan

Publikováno v: ChemInform. 22

Several 2'-fluoroarabino-2',3'-dideoxy- and 2'-fluoro-2',3'-unsaturated 2',3'-dideoxy pyrimidine nucleoside analogues are reported. The saturated analogues 1-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)thymine (2'-threo-FddT, 33), 1-(2,3-dideox

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2428c498061c4214d352e35096fd5988
https://doi.org/10.1002/chin.199104323

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Anticancer Activity of Various 3′-Deoxy Pyrimidine Nucleoside Analogues and Crystal Structure of 1-(3-Deoxy-β-D- threo-pentofuranosyl)cytosine

Autor: I. Ghazzouli, Yung-Chi Cheng, J.‐S. Feng, Shen Zy, George I. Birnbaum, V. Brankovan, G.‐D. Hsiung, J. Giziewicz, J.‐H. Yang, Mao-Chin Liu, Tai-Shun Lin, William H. Prusoff

Publikováno v: ChemInform. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::56b148444654982d3205724ba220b17c
https://doi.org/10.1002/chin.199139238

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Antiviral Evaluation of 3′-Branched Nucleoside Analogs

Autor: M. M. Mansuri, Sterzycki Roman Z, John C. Martin, M. Wittmann, V. Brankovan, Hyekyung Yang, Michael J. M. Hitchcock

Publikováno v: ChemInform. 22

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::136c36848381e742927a6c593786a54b
https://doi.org/10.1002/chin.199143266

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Antiviral Activity of Methyl Derivatives of 9-(2-( Phosphonomethoxy)ethyl)guanine

Autor: V. Brankovan, A K Patick, R. Datema, John C. Martin, Hyekyung Yang, Joanne J. Bronson, Kuo Long Yu, Michael J. M. Hitchcock, M. Alam

Publikováno v: ChemInform. 23

A number of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine (PMEG, 1) have been synthesized and tested in vitro for anti-herpes and anti-human immunodeficiency virus (HIV) activity. Among these analogues, (R)-2'-methyl-PMEG [(R)-3] and 2',

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f1814d9f9a2424b093fdc54a11ac3c6
https://doi.org/10.1002/chin.199252242

Zobrazit plný text záznamu

ChemInform Abstract: Preparation of the Geometric Isomers (I) - (IV) of DDC, DDA, D4C, and D4T as Potential anti-HIV Agents

Autor: M. M. Mansuri, V. Brankovan, J. E. Jun. Starrett, Daniel A. Benigni, John C. Martin, Vittorio Farina

Publikováno v: ChemInform. 23

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d96a33cf569f2523a9f8f89a24de905
https://doi.org/10.1002/chin.199239292

Zobrazit plný text záznamu

ChemInform Abstract: Synthesis and Antiviral Activity of 2′-Substituted 9-(2-( Phosphonomethoxy)ethyl)guanine Analogues

Autor: V. Brankovan, M. Alam, Joanne J. Bronson, Kuo Long Yu, A K Patick, R. Datema, Hyekyung Yang, Michael J. M. Hitchcock, J. C. Martin

Publikováno v: ChemInform. 25

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1191c3942e7c7c582ffe11e049f73081
https://doi.org/10.1002/chin.199410223

Zobrazit plný text záznamu

Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine

Autor: Hyekyung Yang, Michael J. M. Hitchcock, M. Alam, A K Patick, R. Datema, V. Brankovan, Joanne J. Bronson, Kuo Long Yu, John C. Martin

Publikováno v: Journal of Medicinal Chemistry. 35:2958-2969

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb7509581f88b238c2d0d63893612f7
https://doi.org/10.1021/jm00094a005

Zobrazit plný text záznamu

Preparation of the geometric isomers of DDC, DDA, D4C and D4T as potential anti-HIV agents

Autor: Daniel A. Benigni, John C. Martin, Vittorio Farina, John E. Starrett, Muzammil M. Mansuri, V. Brankovan

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 1:65-68

β-L-ddC ( 5 ), β-L-ddA ( 7 ), β-L-d4T ( 7 ) and β-L-d4C ( 8 ) (enantiomers of natural dideoxynucleoside analogues with known potent HIV activity) were prepared as potential anti-HIV agents.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31271dcd4fb648b191a583f6a465b2c1
https://doi.org/10.1016/s0960-894x(01)81093-3

Zobrazit plný text záznamu

Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides

Autor: J. C. Martin, Sterzycki Roman Z, Muzammil M. Mansuri, V. Brankovan, Ismail Ghazzouli

Publikováno v: Journal of medicinal chemistry. 33(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91405681fef3a1bb7af673e0dd68693a
https://pubmed.ncbi.nlm.nih.gov/2165162

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání