Zobrazeno 1 - 10
of 4 887
pro vyhledávání: '"V, Bock"'
Autor:
Simon M. Lauer, Maren Reepmeyer, Ole Berendes, Dorota Klepacki, Jakob Gasse, Sara Gabrielli, Helmut Grubmüller, Lars V. Bock, Andor Krizsan, Rainer Nikolay, Christian M. T. Spahn, Ralf Hoffmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Proline-rich antimicrobial peptides (PrAMPs) inhibit bacterial protein biosynthesis by binding to the polypeptide exit tunnel (PET) near the peptidyl transferase center. Api137, an optimized derivative of honeybee PrAMP apidaecin, inhibits p
Externí odkaz:
https://doaj.org/article/6067bc78e2dd47b68285bb91c3a91b6d
Autor:
Martino Morici, Sara Gabrielli, Keigo Fujiwara, Helge Paternoga, Bertrand Beckert, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Arrest peptides containing RAPP (ArgAlaProPro) motifs have been discovered in both Gram-positive and Gram-negative bacteria, where they are thought to regulate expression of important protein localization machinery components. Here we determ
Externí odkaz:
https://doaj.org/article/7bb148fa3087456198fc966a68df11f9
Autor:
Felix Gersteuer, Martino Morici, Sara Gabrielli, Keigo Fujiwara, Haaris A. Safdari, Helge Paternoga, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Nascent polypeptide chains can induce translational stalling to regulate gene expression. This is exemplified by the E. coli secretion monitor (SecM) arrest peptide that induces translational stalling to regulate expression of the downstream
Externí odkaz:
https://doaj.org/article/73596d597f1f42cfaa8ac810322d5c48
Autor:
Martino Morici, Sara Gabrielli, Keigo Fujiwara, Helge Paternoga, Bertrand Beckert, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/afb6c7fda3c64b749bca30d8bbbdb214
Autor:
Felix Gersteuer, Martino Morici, Sara Gabrielli, Keigo Fujiwara, Haaris A. Safdari, Helge Paternoga, Lars V. Bock, Shinobu Chiba, Daniel N. Wilson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/fd9d02b7221b436ab51beac2d3d5dc4e
Akademický článek
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Akademický článek
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Autor:
Lars V. Bock, Helmut Grubmüller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The rapid temperature drop during plunge-freezing affects the structural ensembles obtained by cryo-EM. To quantify the extent of perturbation, Bock and Grubmüller combined continuum calculations, MD simulations, and kinetic models.
Externí odkaz:
https://doaj.org/article/a6b6b8b56ca94c4685df80659654c19f
Autor:
Bertrand Beckert, Elodie C. Leroy, Shanmugapriya Sothiselvam, Lars V. Bock, Maxim S. Svetlov, Michael Graf, Stefan Arenz, Maha Abdelshahid, Britta Seip, Helmut Grubmüller, Alexander S. Mankin, C. Axel Innis, Nora Vázquez-Laslop, Daniel N. Wilson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Macrolides and ketolides antibiotics selectively interfere with the translation of a specific subset of proteins. Here the authors show how the macrolide erythromycin and the ketolide telithromycin interplay with the nascent polypeptide chain to arre
Externí odkaz:
https://doaj.org/article/15117e74a84f4129bf14254d7d049216
Autor:
Wassermann, Felix
Publikováno v:
Monatshefte, 1976 Jul 01. 68(2), 233-234.
Externí odkaz:
https://www.jstor.org/stable/30156702