Zobrazeno 1 - 10
of 804
pro vyhledávání: '"V, Billard"'
Autor:
Adam E. Hall, Sebastian Öther-Gee Pohl, Patrizia Cammareri, Stuart Aitken, Nicholas T. Younger, Michela Raponi, Caroline V. Billard, Alfonso Bolado Carrancio, Aslihan Bastem, Paz Freile, Fiona Haward, Ian R. Adams, Javier F. Caceres, Paula Preyzner, Alex von Kriegsheim, Malcolm G. Dunlop, Farhat V. Din, Kevin B. Myant
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
The influence of mRNA splicing on colon cancer development and progression is unclear. In this study, the authors demonstrate that the SRSF1 splicing factor is essential to sustain the stem cell phenotype of WNT-activated colorectal cancers.
Externí odkaz:
https://doaj.org/article/b084ea4f47254a91b5543e19fe89996c
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Abstract RAC1B is a tumour-related alternative splice isoform of the small GTPase RAC1, found overexpressed in a large number of tumour types. Building evidence suggests it promotes tumour progression but compelling in vivo evidence, demonstrating a
Externí odkaz:
https://doaj.org/article/381b458820c14084a39556c04ee2ac1d
Autor:
Victoria Gudiño, Sebastian Öther-Gee Pohl, Caroline V. Billard, Patrizia Cammareri, Alfonso Bolado, Stuart Aitken, David Stevenson, Adam E. Hall, Mark Agostino, John Cassidy, Colin Nixon, Alex von Kriegsheim, Paz Freile, Linda Popplewell, George Dickson, Laura Murphy, Ann Wheeler, Malcolm Dunlop, Farhat Din, Douglas Strathdee, Owen J. Sansom, Kevin B. Myant
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
RAC1 is a downstream target of the Wnt signaling that promotes intestinal stem cell expansion and tumorigenesis. Here, the authors identify the specific splice variant RAC1B as an important mediator of colorectal tumourigenesis and a potential target
Externí odkaz:
https://doaj.org/article/0d5fa07d90ab4bcca894bd613a859024
Bibliography: 455-480.
xiv, 480 leaves : ill. ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
This thesis examines female illiteracy in rural China, bearing i
xiv, 480 leaves : ill. ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
This thesis examines female illiteracy in rural China, bearing i
Externí odkaz:
http://hdl.handle.net/2440/19727
Autor:
de Broca, A.
Publikováno v:
Éthique & Santé; December 2018, Vol. 15 Issue: 4 p264-264, 1p
Autor:
George Dickson, Linda Popplewell, Farhat V N Din, Adam E. Hall, Kevin Myant, Malcolm G. Dunlop, Paz Freile, Alfonso Bolado, Caroline V. Billard, Victoria Gudiño, Stuart Aitken, Mark Agostino, David A. Stevenson, Douglas Strathdee, Laura Murphy, Owen J. Sansom, Alex von Kriegsheim, Sebastian Öther-Gee Pohl, John W. Cassidy, Patrizia Cammareri, Colin Nixon, Ann P. Wheeler
Publikováno v:
Nature Communications
Gudiño, V, Öther-Gee Pohl, S, V Billard, C, Cammareri, P, Bolado Carrancio, A, Aitken, S, Stevenson, D, Hall, A, Agostino, M, Cassidy, J, Nixon, C, von Kriegsheim, A, Friele, P, Popplewell, L, Dickson, G, Murphy, L, Wheeler, A P, Dunlop, M G, Din, F V N, Strathdee, D, J. Sansom, O & Myant, K B 2021, ' Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways ', Nature Communications . https://doi.org/10.1038/s41467-021-22531-3
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Gudiño, V, Öther-Gee Pohl, S, V Billard, C, Cammareri, P, Bolado Carrancio, A, Aitken, S, Stevenson, D, Hall, A, Agostino, M, Cassidy, J, Nixon, C, von Kriegsheim, A, Friele, P, Popplewell, L, Dickson, G, Murphy, L, Wheeler, A P, Dunlop, M G, Din, F V N, Strathdee, D, J. Sansom, O & Myant, K B 2021, ' Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways ', Nature Communications . https://doi.org/10.1038/s41467-021-22531-3
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Current therapeutic options for treating colorectal cancer have little clinical efficacy and acquired resistance during treatment is common, even following patient stratification. Understanding the mechanisms that promote therapy resistance may lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d761f8e664c9c0e74b157a8fb7baff43
https://eprints.gla.ac.uk/239120/1/239120.pdf
https://eprints.gla.ac.uk/239120/1/239120.pdf
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 10, Pp 1-12 (2021)
Cell Death & Disease
RAC1B is a tumour-related alternative splice isoform of the small GTPase RAC1, found overexpressed in a large number of tumour types. Building evidence suggests it promotes tumour progression but compelling in vivo evidence, demonstrating a role in d
Autor:
Aurélien Venara, Jean-Francois Hamel, Laura Beyer-Berjot, Timothée Vignaud, Karem Slim, M. Abderrazak, H. Abolo, N. Abras, M. Aissou, S. Albertini, P. Alfonsi, A. Andre, J.M. Arimont, L. Arnalsteen, J. Atger, A. Attias, O. Aumont, S. Auvray, R. Bachmann, G. Barabino, P. Barsotti, B. Beauchesne, N. Beaupel, A. Beliard, A. Bellouard, H. Beloeil, F. Ben Salem, A. Benhamou, V. Billard, M. Binhas, D. Binot, J.L. Blache, A. Blet, J.P. Bongiovanni, A. Bonnal, M. Bonnet, H. Boret, A.E. Bossard, H. Bothereau, N. Bouarroudj, A. Bouayed, F. Bouchard, M. Boumadani, M. Bousquet, V. Bouygues, G. Bozio, A. Brek, P. Cadi, P. Caillon, A. Camerlo, C. Capito, J.L. Cardin, M. Castiglioni, M.L. Catinois, P. Cattan, C. Chambrier, G. Chambrier, O. Chapuis, M. Chauvin, S. Chokairi, X. Chopin Laly, V. Collange, E. Cotte, E. Cuellar, E. D'errico, S. Dahmani, M. Danan, C. De La Fontaine, P. De Wailly, C. Degauque, F. Delacoste, C. Denet, Q. Denost, P. Desaint, E. Descamps, V Desfourneaux., J. Desmet, G. Desolneux, S. Dileon, J.B. Dolbeau, R. Douard, F. Dufour, E. Dupont-Bierre, A. Dupré, A. Entremont, J.L. Faucheron, P. Fernoux, S. Figuet, A. Finianos, R. Flamein, D. Fletcher, J.P. Fontes, E. Fourn, S. Gergeanu, A. Germain, B. Gignoux, P. Goater, P Gres., M. Grigoroiu, P. Grillo, B. Guignard, D. Guinier, J.L. Guiot, C. Gutton, H. Hadjadj, K. Hail, M.H. Hausermann, S. Hennequin, B. Homsy-Hubert, S. Jambet, T. Janecki, V. Jannier-Guillou, J. Jaspart, F. Joly, J. Joris, F. Journe, F. Kattou, G. Kemoun, M. Khalaf, F. Klack, K. Kothonidis, O. Kurdi, A. Laforest, A. Lamblin, S. Lammens, S. Laporte, M.V. Launay-Savary, A.L. Le Maho, J.M. Lemée, D. Leonard, J. Leporrier, J.L. Lorin, E. Magne, F. Maisonnette, V. Malherbe, G. Manceau, P. Mariani, D. Massalou, J.L. Massard, F. Mauvais, J. Mbuyamba, J. Mbuyamba Katapile, T. Mehila, H. Meillat, C. Mergui, P. Michaud, F. Milou, F. Mirre, C. Mor Martinez, S. Mouchon, F. Mouilhade, Y.L. Nguyen, S. Ostermann Bucher, M. Page, S. Parent, A.L. Payen, R. Pedicone, P. Peluchon, V. Pichot-Delahaye, A. Piquard, I. Pirlet, L. Plard, M. Poiblanc, G. Poinas, J. Poincenot, C. Ponchel, A. Pontallier, R. Pop, E. Potiron, J.M. Proske, B. Prunet, E. Ras, O. Raspado, M. Raux, J.M. Regimbeau, C. Remue, F. Renacco, R. Riboud, A.L. Richard-Payen, D. Rio, M. Sage, P.Y. Sage, M. Saint Denis, P. Salaun, B. Samyn, M. Sbai Idrissi, G. Schmitt, E. Secq, A. Seddiki, N. Sens, D. Sirieix, F. Siriser, M. Tarcea, M. Tavernier, B. Tete, O. Theissen-Laval, A. Thevenot, R. Thievenaz, B. Vacher, R. Verhaeghe, J.F. Verrier, C. Vieuille, C. Voilin, C. Vuagnat, S. Zaepfel
Publikováno v:
Surgery Open Digestive Advance. 2:100009
Introduction Postoperative ileus(POI) and anastomotic leakage(AL) are highly associated but the direction of this link is unknown. Indeed, it has traditionally been stated that AL leads to POI(secondary POI). The objective was to statistically determ
Autor:
S. Achkar, M. Andraud, E. Romano, C. Haie-Meder, M. Kissel, M.H. Ta, A. Duhamel, Cyrus Chargari, G. Boulle, B. Celestin, L. Bordenave, T. Kumar, V. Billard, R. Bourdais, A. Pounou
Publikováno v:
Radiotherapy and Oncology. 158:S142
Publikováno v:
Journal of Crohn's and Colitis. 14:S150-S150
Background Current mouse models of colitis-associated cancer often utilise a combination of APC mutation, Dextran sulphate sodium (DSS) and azoxymethane administration. However, only 13% of human inflammatory bowel disease (IBD)-associated cancers is