Enhanced TAG-72 expression and tumor uptake of radiolabeled monoclonal antibody CC49 in metastatic breast cancer patients following alpha-interferon treatment

Autor: J L, Murray, D J, Macey, E J, Grant, M G, Rosenblum, L P, Kasi, H Z, Zhang, R L, Katz, P T, Riger, D, LeBherz, V, Bhadkamkar

Publikováno v: Cancer research. 55

The IFNs, alpha and gamma, have been shown to enhance the tumor-associated glycoprotein (TAG-72) on adenocarcinoma cells in vitro and in mice with human breast cancer xenografts, resulting in improved targeting of monoclonal antibody CC49. To determi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3fabd687a832e57baa664b2e84a01ca1
https://pubmed.ncbi.nlm.nih.gov/7493372

Indium-111-labeled B72.3 monoclonal antibody in the detection and staging of breast cancer: a phase I study

Autor: L M, Lamki, A U, Buzdar, S E, Singletary, M G, Rosenblum, V, Bhadkamkar, L, Esparza, D A, Podoloff, A, Zukiwski, G N, Hortobagyi, J L, Murray

Publikováno v: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 32(7)

Sixteen patients with primary breast cancer were studied with a pancarcinoma monoclonal antibody B72.3, an IgG1 molecule directed against tumor-associated glycoprotein (TAG-72) present in several tumors. Five millicuries of 111In was used to label 0.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d134bea08e291f64c56cf8128d0aeb50
https://pubmed.ncbi.nlm.nih.gov/2066785

Prenatal Phenotype of Alkuraya-Kučinskas Syndrome: A Novel Case and Systematic Literature Review.

Autor: Rice SM; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Varotsis DF; Department of Obstetrics and Gynecology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Wodoslawsky S; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Critchlow E; Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Liu R; Revvity Omics, Inc., Waltham, Massachusetts, USA., McLaren RA Jr; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Makhamreh MM; Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn, New York, USA., Firman B; Department of Obstetrics and Gynecology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Berger SI; Center for Genetic Medicine Research at Children's National Hospital, Washington, DC, USA., Al-Kouatly HB; Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

Publikováno v: Prenatal diagnosis [Prenat Diagn] 2024 Oct; Vol. 44 (11), pp. 1381-1397. Date of Electronic Publication: 2024 Sep 03.

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