Zobrazeno 1 - 10
of 112
pro vyhledávání: '"V, Beale"'
Autor:
Anna J. Warren, Jose Trincao, Adam D. Crawshaw, Emma V. Beale, Graham Duller, Andrew Stallwood, Mark Lunnon, Richard Littlewood, Adam Prescott, Andrew Foster, Neil Smith, Guenther Rehm, Sandira Gayadeen, Christopher Bloomer, Lucia Alianelli, David Laundy, John Sutter, Leo Cahill, Gwyndaf Evans
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 6, Pp 1593-1608 (2024)
VMXm joins the suite of operational macromolecular crystallography beamlines at Diamond Light Source. It has been designed to optimize rotation data collections from protein crystals less than 10 µm and down to below 1 µm in size. The beamline has
Externí odkaz:
https://doaj.org/article/6a6364759ca64e4ca49e9f37a9c3e3a8
Autor:
Maximilian Wranik, Michal W. Kepa, Emma V. Beale, Daniel James, Quentin Bertrand, Tobias Weinert, Antonia Furrer, Hannah Glover, Dardan Gashi, Melissa Carrillo, Yasushi Kondo, Robin T. Stipp, Georgii Khusainov, Karol Nass, Dmitry Ozerov, Claudio Cirelli, Philip J. M. Johnson, Florian Dworkowski, John H. Beale, Scott Stubbs, Thierry Zamofing, Marco Schneider, Kristina Krauskopf, Li Gao, Oliver Thorn-Seshold, Christoph Bostedt, Camila Bacellar, Michel O. Steinmetz, Christopher Milne, Jörg Standfuss
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Serial crystallography at X-ray free-electron lasers (XFELs) permits the determination of radiation-damage free static as well as time-resolved protein structures at room temperature. Efficient sample delivery is a key factor for such experi
Externí odkaz:
https://doaj.org/article/f224092cc9184c46b2af0e3942817cf2
Autor:
Emma V. Beale, Anna J. Warren, José Trincão, James Beilsten-Edmands, Adam D. Crawshaw, Geoff Sutton, David Stuart, Gwyndaf Evans
Publikováno v:
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
Developing methods to determine high-resolution structures from micrometre- or even submicrometre-sized protein crystals has become increasingly important in recent years. This applies to both large protein complexes and membrane proteins, where prot
Externí odkaz:
https://doaj.org/article/97953cece9ad46f69d67226b4d3ea88b
Autor:
Emma V. Beale, David G. Waterman, Corey Hecksel, Jason van Rooyen, James B. Gilchrist, James M. Parkhurst, Felix de Haas, Bart Buijsse, Gwyndaf Evans, Peijun Zhang
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
MicroED has recently emerged as a powerful method for the analysis of biological structures at atomic resolution. This technique has been largely limited to protein nanocrystals which grow either as needles or plates measuring only a few hundred nano
Externí odkaz:
https://doaj.org/article/a360773de2214620ac65ecc967425cdd
Akademický článek
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Akademický článek
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Autor:
David I. Stuart, Gwyndaf Evans, Adam D. Crawshaw, Anna J. Warren, Emma V Beale, James Beilsten-Edmands, Geoff Sutton, José Trincão
Publikováno v:
IUCrJ
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
IUCrJ, Vol 7, Iss 3, Pp 500-508 (2020)
Protein crystals exposed to a scanning electron microscope beam were analysed using X-ray diffraction to assess the impact of electrons on crystal quality. These experiments support the use of a scanning electron microscope as an imaging tool for loc
Autor:
Andrea Cellini, Madan Kumar Shankar, Weixiao Yuan Wahlgren, Amke Nimmrich, Antonia Furrer, Daniel James, Maximilian Wranik, Sylvain Aumonier, Emma V. Beale, Florian Dworkowski, Jörg Standfuss, Tobias Weinert, Sebastian Westenhoff
Publikováno v:
Chemical communications (Cambridge, England). 58(31)
We present the structure of a photoactivated animal (6-4) photolyase in its radical pair state, captured by serial crystallography. We observe how a conserved asparigine moves towards the semiquinone FAD chromophore and stabilizes it by hydrogen bond
Autor:
John H. Beale, Ivo Tews, Michael A. Hough, Emma V Beale, A. Ebrahim, Rachel Bolton, Stephen A. Marshall, Jonathan A. R. Worrall, T. Moreno-Chicano, Robin L. Owen, Stephen B. Carr
Publikováno v:
Journal of Applied Crystallography
Some ideas and methods on how to produce high-quality samples for successful serial crystallography experiments are presented. The methods here described are aimed at experimenters trying to convert their vapour diffusion crystallization conditions i
Autor:
Graham Duller, Andrew Stallwood, Emma V Beale, Gwyndaf Evans, José Trincão, Adam D. Crawshaw, Anna J. Warren
Publikováno v:
Journal of Visualized Experiments
The mounting of microcrystals (