Bacterial Internalization, Localization, and Effectors Shape the Epithelial Immune Response during Shigella flexneri Infection

Autor: Uyanga Tamir, Helen K. W. Law, Benno Schwikowski, Frederik Gwinner, Camille Rey, Jost Enninga, Juliane Lippmann

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2015, 83 (9), pp.3624-3637. ⟨10.1128/IAI.00574-15⟩
Infection and Immunity, 2015, 83 (9), pp.3624-3637. ⟨10.1128/IAI.00574-15⟩

Intracellular pathogens are differentially sensed by the compartmentalized host immune system. Nevertheless, gene expression studies of infected cells commonly average the immune responses, neglecting the precise pathogen localization. To overcome th

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