The effect of paclitaxel on apoptosis, autophagy and mitotic catastrophe in AGS cells

Autor: Tin Myo Khing, Won Seok Choi, Dong Min Kim, Wah Wah Po, Wynn Thein, Chang Yell Shin, Uy Dong Sohn

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)

Abstract Paclitaxel is an anti-microtubule agent that has been shown to induce cell death in gastric cancer. However, the detailed mechanism of action is unclear. In this study, we reveal that the paclitaxel-induced cell death mechanism involves mito

Externí odkaz: https://doaj.org/article/52b6d767d8ba4666901a76ef4e5a0b53

Vinpocetine alleviates lung inflammation via macrophage inflammatory protein-1β inhibition in an ovalbumin-induced allergic asthma model.

Autor: Won Seok Choi, Hyun Sik Kang, Hong Jo Kim, Wang Tae Lee, Uy Dong Sohn, Ji-Yun Lee

Publikováno v: PLoS ONE, Vol 16, Iss 4, p e0251012 (2021)

Asthma is a well-known bronchial disease that causes bronchial inflammation, narrowing of the bronchial tubes, and bronchial mucus secretion, leading to bronchial blockade. In this study, we investigated the association between phosphodiesterase (PDE

Externí odkaz: https://doaj.org/article/f2707911689542629f8e08c4eeb89f32

Protective effect of ultrasonication-processed ginseng berry extract on the D-galactosamine/lipopolysaccharide-induced liver injury model in rats

Autor: Yoonjin Nam, Jinhyung Bae, Ji Hoon Jeong, Sung Kwon Ko, Uy Dong Sohn

Publikováno v: Journal of Ginseng Research, Vol 42, Iss 4, Pp 540-548 (2018)

Background: Acute hepatic failure is a life-threatening critical condition associated with rapid deterioration of liver function and liver transplantation. Several studies have shown that Panax ginseng Mayer has antidiabetic and hepatoprotective effe

Externí odkaz: https://doaj.org/article/31df625ce4304390a0a28c2ea50c2ede

Improved motility in the gastrointestinal tract of a postoperative ileus rat model with ilaprazole

Autor: Won Seok Choi, Geon Min Kim, Uy Dong Sohn, Hee Ju Sohn

Publikováno v: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

Postoperative ileus (POI), a symptom that occurs after abdominal surgery, reduces gastrointestinal motility. Although its mechanism is unclear, POI symptoms are known to be caused by inflammation 6 to 72 h after surgery. As proton pump inhibitors exh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbed2864f6f49c6e47d366cf1b81a5f
https://doi.org/10.4196/kjpp.2021.25.6.507

The Effect of DA-9701 on 5-Hydroxytryptamine-Induced Contraction of Feline Esophageal Smooth Muscle Cells

Autor: Kyung Hoon Oh, Yoonjin Nam, Ji Hoon Jeong, In Kyeom Kim, Uy Dong Sohn

Publikováno v: Molecules, Vol 19, Iss 4, Pp 5135-5149 (2014)

Serotonin, or 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter found in blood platelets, the gastrointestinal (GI) tract, and the central nervous system (CNS) of animals and humans. The signaling pathways of 5-hydroxytryptamine (5-HT)-indu

Externí odkaz: https://doaj.org/article/613ca9f460cc4cdf9c27e725a1c50ec5