Zobrazeno 1 - 10
of 380
pro vyhledávání: '"Uy-Dong Sohn"'
Autor:
Seung In Um, Uy Dong Sohn, Sun-Young Jung, Seung-Hun You, Changone Kim, Sora Lee, Heesang Lee
Publikováno v:
Health Research Policy and Systems, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background The pharmaceutical industry is heavily regulated. Partly for this reason, new drugs generally take over 10 years from the product development stage to market entry. Although regulations affect the pharmaceutical industry over a lo
Externí odkaz:
https://doaj.org/article/e43a82d90ac242e192416cee769887c7
Autor:
Tin Myo Khing, Won Seok Choi, Dong Min Kim, Wah Wah Po, Wynn Thein, Chang Yell Shin, Uy Dong Sohn
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract Paclitaxel is an anti-microtubule agent that has been shown to induce cell death in gastric cancer. However, the detailed mechanism of action is unclear. In this study, we reveal that the paclitaxel-induced cell death mechanism involves mito
Externí odkaz:
https://doaj.org/article/52b6d767d8ba4666901a76ef4e5a0b53
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 4, Pp 606-617 (2019)
Background: The Panax ginseng berry extract (GBE) is well known to have an antidiabetic effect. The aim of this study is to evaluate and investigate the protective effect of ultrasonication-processed P. ginseng berry extract (UGBE) compared with GBE
Externí odkaz:
https://doaj.org/article/8188a6c4be654aec9af300706e5e2c4e
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0251012 (2021)
Asthma is a well-known bronchial disease that causes bronchial inflammation, narrowing of the bronchial tubes, and bronchial mucus secretion, leading to bronchial blockade. In this study, we investigated the association between phosphodiesterase (PDE
Externí odkaz:
https://doaj.org/article/f2707911689542629f8e08c4eeb89f32
Publikováno v:
Drug Targets and Therapeutics. 2:19-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34127e78402180d9d0530394cb718959
https://doi.org/10.58502/dtt.23.0008
https://doi.org/10.58502/dtt.23.0008
Publikováno v:
Journal of Ginseng Research, Vol 42, Iss 4, Pp 540-548 (2018)
Background: Acute hepatic failure is a life-threatening critical condition associated with rapid deterioration of liver function and liver transplantation. Several studies have shown that Panax ginseng Mayer has antidiabetic and hepatoprotective effe
Externí odkaz:
https://doaj.org/article/31df625ce4304390a0a28c2ea50c2ede
Autor:
Uy Dong Sohn, Young Sil Min, Won Pill Jung, Hyun Dong Je, Fanxue Jin, Joon Seok Bang, Hyuk-Jun Yoon
Publikováno v:
Biomolecules & Therapeutics. 30:145-150
In this study, we investigated the influence of galangin on vascular contractibility and to determine the mechanism underlying the relaxation. Isometric contractions of denuded aortic muscles were recorded and combined with western blot analysis whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889c0d8265f2c6ad29d433739917bed5
https://doi.org/10.4062/biomolther.2021.087
https://doi.org/10.4062/biomolther.2021.087
Publikováno v:
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
Postoperative ileus (POI), a symptom that occurs after abdominal surgery, reduces gastrointestinal motility. Although its mechanism is unclear, POI symptoms are known to be caused by inflammation 6 to 72 h after surgery. As proton pump inhibitors exh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbed2864f6f49c6e47d366cf1b81a5f
https://doi.org/10.4196/kjpp.2021.25.6.507
https://doi.org/10.4196/kjpp.2021.25.6.507
Publikováno v:
Biomolecules & Therapeutics
In this study, we aimed to investigate the effects of 8 weeks of treatment with a combination of evogliptin and leucine, a branched-chain amino acid, in mice with high-fat diet (HFD)-induced diabetes. Treatment with evogliptin alone or in combination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0803eb96fc090603a45519ba400fc44c
https://doi.org/10.4062/biomolther.2021.003
https://doi.org/10.4062/biomolther.2021.003
Publikováno v:
Molecules, Vol 19, Iss 4, Pp 5135-5149 (2014)
Serotonin, or 5-hydroxytryptamine (5-HT), is a monoamine neurotransmitter found in blood platelets, the gastrointestinal (GI) tract, and the central nervous system (CNS) of animals and humans. The signaling pathways of 5-hydroxytryptamine (5-HT)-indu
Externí odkaz:
https://doaj.org/article/613ca9f460cc4cdf9c27e725a1c50ec5