Zobrazeno 1 - 10
of 720
pro vyhledávání: '"Uwe. T. Bornscheuer"'
Autor:
Irena Beidler, Nicola Steinke, Tim Schulze, Chandni Sidhu, Daniel Bartosik, Marie-Katherin Zühlke, Laura Torres Martin, Joris Krull, Theresa Dutschei, Borja Ferrero-Bordera, Julia Rielicke, Vaikhari Kale, Thomas Sura, Anke Trautwein-Schult, Inga V. Kirstein, Karen H. Wiltshire, Hanno Teeling, Dörte Becher, Mia Maria Bengtsson, Jan-Hendrik Hehemann, Uwe. T. Bornscheuer, Rudolf I. Amann, Thomas Schweder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Phytoplankton blooms provoke bacterioplankton blooms, from which bacterial biomass (necromass) is released via increased zooplankton grazing and viral lysis. While bacterial consumption of algal biomass during blooms is well-studied, little
Externí odkaz:
https://doaj.org/article/e17e8a4f63ef45ea8045d12a7c6be836
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Xylanases are important for the enzymatic breakdown of lignocellulose-based biomass to produce biofuels and other value-added products. We report functional and structural analyses of TsaGH11, an endo-1,4-β-xylanase from the hemicellulose-d
Externí odkaz:
https://doaj.org/article/64319ea1230c4303a2fa7b1da53b4028
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4488-4496 (2023)
Enzymes are potent catalysts with high specificity and selectivity. To leverage nature’s synthetic potential for industrial applications, various protein engineering techniques have emerged which allow to tailor the catalytic, biophysical, and mole
Externí odkaz:
https://doaj.org/article/72d5887bda0d45d2a56f6793e1b1a89e
Autor:
Shuke Wu, Chao Xiang, Yi Zhou, Mohammad Saiful Hasan Khan, Weidong Liu, Christian G. Feiler, Ren Wei, Gert Weber, Matthias Höhne, Uwe T. Bornscheuer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Fast screening of enzymes is key for directed evolution of industrial biocatalysts. Here, the authors report a simple, high-throughput, and low-equipment-dependent growth selection system for engineering three enzymes for synthesis of chiral amines.
Externí odkaz:
https://doaj.org/article/daa9820f5ef346a0806e953ac1ba04dc
Autor:
Theresa Dutschei, Marie-Katherin Zühlke, Norma Welsch, Tom Eisenack, Maximilian Hilkmann, Joris Krull, Carlo Stühle, Stefan Brott, Alexandra Dürwald, Lukas Reisky, Jan-Hendrik Hehemann, Dörte Becher, Thomas Schweder, Uwe T. Bornscheuer
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background Marine algae are responsible for half of the global primary production, converting carbon dioxide into organic compounds like carbohydrates. Particularly in eutrophic waters, they can grow into massive algal blooms. This polysacch
Externí odkaz:
https://doaj.org/article/31f17d16bc644a6c985be52a0fdcaa8f
Autor:
Haijin Tian, Christoph Furtmann, Florian Lenz, Vishnu Srinivasamurthy, Uwe T. Bornscheuer, Joachim Jose
Publikováno v:
Microbial Biotechnology, Vol 15, Iss 8, Pp 2235-2249 (2022)
Summary The application of enzymes as biocatalysts in industrial processes has great potential due to their outstanding stereo‐, regio‐ and chemoselectivity. Using autodisplay, enzymes can be immobilized on the cell surface of Gram‐negative bac
Externí odkaz:
https://doaj.org/article/e3f63865c91e45089c502a0e53f047fe
Publikováno v:
Catalysts, Vol 13, Iss 11, p 1405 (2023)
Endo-1,4-β-xylanases belonging to the glycoside hydrolase (GH) 11 family hydrolyze the β-1,4-glycosidic linkages in the xylan backbone to convert polymeric xylan into xylooligosaccharides. GH11 xylanases play an essential role in sugar metabolism a
Externí odkaz:
https://doaj.org/article/31e36a47f24e439c9cb6f52213106ae5
Autor:
Johannes Büchler, Sumire Honda Malca, David Patsch, Moritz Voss, Nicholas J. Turner, Uwe T. Bornscheuer, Oliver Allemann, Camille Le Chapelain, Alexandre Lumbroso, Olivier Loiseleur, Rebecca Buller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
The late-stage functionalization of unactivated carbon–hydrogen bonds is a difficult but important task, which has been met with promising but limited success through synthetic organic chemistry. Here the authors use machine learning to engineer We
Externí odkaz:
https://doaj.org/article/b0080e192c1f4807837af8d63df4a6df
Autor:
Arne Stamm, Johannes Öhlin, Caroline Mosbech, Peter Olsén, Boyang Guo, Elisabeth Söderberg, Antonino Biundo, Linda Fogelström, Shubhankar Bhattacharyya, Uwe T. Bornscheuer, Eva Malmström, Per-Olof Syrén
Publikováno v:
JACS Au, Vol 1, Iss 11, Pp 1949-1960 (2021)
Externí odkaz:
https://doaj.org/article/5d17fc636e334cfdb511c23e9891b752
Autor:
Andrea Schenkmayerova, Gaspar P. Pinto, Martin Toul, Martin Marek, Lenka Hernychova, Joan Planas-Iglesias, Veronika Daniel Liskova, Daniel Pluskal, Michal Vasina, Stephane Emond, Mark Dörr, Radka Chaloupkova, David Bednar, Zbynek Prokop, Florian Hollfelder, Uwe T. Bornscheuer, Jiri Damborsky
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Directed evolution commonly relies on point mutations but InDels frequently occur in evolution. Here the authors report a protein-engineering framework based on InDel mutagenesis and fragment transplantation resulting in greater catalysis and longer
Externí odkaz:
https://doaj.org/article/3c18b7a5373d42f0b49ea5eb1b1dcbad