Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Uwe Trefzer"'
Publikováno v:
Case Reports in Dermatology, Vol 6, Iss 1, Pp 34-36 (2014)
Tremelimumab is a fully human monoclonal antibody specific for human cytotoxic T lymphocyte-associated antigen 4. Administration of tremelimumab to patients with locally advanced and metastatic melanoma has resulted in a subset of patients with durab
Externí odkaz:
https://doaj.org/article/ed98a52d3b3f402cbe6b906dd2ae57a6
Autor:
Caroline J Voskens, Simone M Goldinger, Carmen Loquai, Caroline Robert, Katharina C Kaehler, Carola Berking, Tanja Bergmann, Clemens L Bockmeyer, Thomas Eigentler, Michael Fluck, Claus Garbe, Ralf Gutzmer, Stephan Grabbe, Axel Hauschild, Rüdiger Hein, Gheorghe Hundorfean, Armin Justich, Ullrich Keller, Christina Klein, Christine Mateus, Peter Mohr, Sylvie Paetzold, Imke Satzger, Dirk Schadendorf, Marc Schlaeppi, Gerold Schuler, Beatrice Schuler-Thurner, Uwe Trefzer, Jens Ulrich, Julia Vaubel, Roger von Moos, Patrik Weder, Tabea Wilhelm, Daniela Göppner, Reinhard Dummer, Lucie M Heinzerling
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53745 (2013)
Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces adverse events (AE) in up to 64% of patients. Treatment algorithms for the management of common ipilimum
Externí odkaz:
https://doaj.org/article/1e9dff99dd604582ac2c2c7a3f9fad75
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5199 (2009)
Proteome serology may complement expression library-based approaches as strategy utilizing the patients' immune responses for the identification pathogenesis factors and potential targets for therapy and markers for diagnosis. Melanoma is a relativel
Externí odkaz:
https://doaj.org/article/ff216657c7d44a5eba7248b6285c3983
Autor:
Dirk Schadendorf, Levi A. Garraway, Gad Getz, Scott L. Carter, Stacey B. Gabriel, Jessica C. Hassel, Benjamin Weide, Carmen Loquai, Uwe Trefzer, Carola Berking, Friederike Egberts, Helen J. Gogas, Selma Ugurel, Simone M. Goldinger, Ralf Gutzmer, Uwe Hillen, Lisa Zimmer, Deborah Farlow, Kristian Cibulskis, Aaron McKenna, Mara Rosenberg, Eran Hodis, Gregory V. Kryukov, Steven Whittaker, Amaro Taylor-Weiner, Chelsea S. Place, Eva M. Goetz, Cory M. Johannessen, Daniel J. Treacy, Antje Sucker, Nikhil Wagle, Eliezer M. Van Allen
PDF file, 12065K, Supplementary Table S4. Complete listing of all somatic mutations seen in all tumors. This table provides details on every non-synonymous mutation or short insertion/deletion observed in this cohort, with data on genomic coordinates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5506ae088ed88f5f363d9c3bc77d56e0
https://doi.org/10.1158/2159-8290.22530882.v1
https://doi.org/10.1158/2159-8290.22530882.v1
Autor:
Dirk Schadendorf, Levi A. Garraway, Gad Getz, Scott L. Carter, Stacey B. Gabriel, Jessica C. Hassel, Benjamin Weide, Carmen Loquai, Uwe Trefzer, Carola Berking, Friederike Egberts, Helen J. Gogas, Selma Ugurel, Simone M. Goldinger, Ralf Gutzmer, Uwe Hillen, Lisa Zimmer, Deborah Farlow, Kristian Cibulskis, Aaron McKenna, Mara Rosenberg, Eran Hodis, Gregory V. Kryukov, Steven Whittaker, Amaro Taylor-Weiner, Chelsea S. Place, Eva M. Goetz, Cory M. Johannessen, Daniel J. Treacy, Antje Sucker, Nikhil Wagle, Eliezer M. Van Allen
PDF file 73K, This file contains legends for the five supplementary tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78b6cf1ac8c8319d26e53969c1823a5a
https://doi.org/10.1158/2159-8290.22530894.v1
https://doi.org/10.1158/2159-8290.22530894.v1
Autor:
Ruth Plummer, Ralf Gutzmer, Anne Lynn S. Chang, John T. Lear, Martin Kaatz, Uwe Trefzer, Alexandros Stratigos, Carmen Loquai, Luc Dirix, Patrick Combemale, Nicholas Squittieri, Karl D. Lewis, Reinhard Dummer, Michael R. Migden, A Guminksi, Ragini R. Kudchadkar, H.-J. Schulze
Publikováno v:
British Journal of Dermatology. 182:1369-1378
Background: Basal cell carcinomas (BCCs) exhibit aberrant activation of the hedgehog pathway. Sonidegib is a hedgehog pathway inhibitor approved for the treatment of locally advanced BCC (laBCC) and metastatic BCC (mBCC) based on primary results of t
Autor:
Carmen Loquai, Ralf Gutzmer, Knuth Rass, Rudolf Stadler, Laura Kerschke, Annette Stein, Erika Richtig, Dirk Schadendorf, Martin Kaatz, Katharina C. Kähler, Jochen Utikal, Uwe Trefzer, Lutz Edler, Jürgen C. Becker, Christoph Höller, Selma Ugurel, Cord Sunderkötter, Carola Berking, Annette Kopp-Schneider, Patrick Terheyden, Michael Fluck
Publikováno v:
Oncotarget
// Selma Ugurel 1, 2 , Carmen Loquai 3 , Patrick Terheyden 4 , Dirk Schadendorf 1, 5 , Erika Richtig 6 , Jochen Utikal 7, 8 , Ralf Gutzmer 9 , Knuth Rass 10 , Cord Sunderkotter 11 , Annette Stein 12 , Michael Fluck 13 , Martin Kaatz 14 , Uwe Trefzer
Autor:
Jürgen C. Becker, Dario Neri, Reinhard Dummer, Claus Garbe, Antonella Romanini, Thomas Eigentler, Benjamin Weide, Chiara Catania, Stefano Cascinu, Giuliano Elia, Axel Hauschild, Paolo A. Ascierto, Uwe Trefzer, Riccardo Danielli
Engineered cytokine products represent promising agents for the treatment of immunogenic tumors, such as malignant melanoma, in addition to immune checkpoint inhibitors. Here we describe the results of a controlled, randomized phase II clinical trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517d23b4d09592e69080df74c5a33f49
https://doi.org/10.5167/uzh-179560
https://doi.org/10.5167/uzh-179560
Autor:
Ralf Gutzmer, Maurizio Podda, Carmen Loquai, Reinhard Dummer, Thomas Haalck, Josef Koller, Michael Weichenthal, Wolfgang Tilgen, Daniela Göppner, Axel Hauschild, Dirk Schadendorf, Norbert H. Brockmeyer, Uwe Trefzer, Annette Stein, Helen Gogas, Peter Mohr, Erhard Hölzle, Lars Alexander Schneider, Cord Sunderkötter, Alexander Enk, Cornelia Mauch
Publikováno v:
Journal of Clinical Oncology. 33:4077-4084
Purpose To evaluate the efficacy, safety, tolerability, and quality of life (QoL) in patients receiving intravenous, intermittent high-dose interferon alfa-2b (IFN-α-2b [iHDI]) compared with standard high-dose IFN-α-2b (HDI). Patient and Methods Pa
Autor:
Ruth Plummer, Martin Kaatz, Alexander Guminski, Patrick Combemale, Karl D. Lewis, Ragini R. Kudchadkar, Manisha Mone, Dalila Sellami, Jocelyn Zhou, Carmen Loquai, Luc Dirix, Anne Lynn S. Chang, Ralf Gutzmer, John T. Lear, Tingting Yi, Michael R. Migden, Reinhard Dummer, Alexandros Stratigos, Uwe Trefzer, Henry Castro
Publikováno v:
Journal of the European Academy of Dermatology and Venereology
Background Patients with locally advanced basal cell carcinoma (laBCC) or metastatic BCC (mBCC), two difficult-to-treat populations, have had limited treatment options. Sonidegib, a hedgehog pathway inhibitor (HPI), was approved in laBCC based on res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c71a42ca781cb5725f0ad8c828de1c
https://www.zora.uzh.ch/id/eprint/143585/
https://www.zora.uzh.ch/id/eprint/143585/