Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Uwe Tessmer"'
Autor:
Juliane Marie Theiss, Thomas Günther, Malik Alawi, Friederike Neumann, Uwe Tessmer, Nicole Fischer, Adam Grundhoff
Publikováno v:
PLoS Pathogens, Vol 11, Iss 7, p e1004974 (2015)
Merkel cell polyomavirus (MCPyV) is considered the etiological agent of Merkel cell carcinoma and persists asymptomatically in the majority of its healthy hosts. Largely due to the lack of appropriate model systems, the mechanisms of viral replicatio
Externí odkaz:
https://doaj.org/article/924ffcf65e874446ae293c93565c6ef4
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004274 (2014)
We have previously demonstrated that acquisition of intricate patterns of activating (H3K4me3, H3K9/K14ac) and repressive (H3K27me3) histone modifications is a hallmark of KSHV latency establishment. The precise molecular mechanisms that shape the la
Externí odkaz:
https://doaj.org/article/6a1da803ba55414db9731f36b8f1116f
Autor:
André Eissmann, Victor Wray, Uwe Tessmer, Torgils Fossen, Karsten Bruns, Ulrich S. Schubert, Alok Sharma, David Mitzner, Nicole Studtrucker, Peter Henklein, René Röder
Publikováno v:
Journal of Biological Chemistry. 282:353-363
Recently, a novel 87-amino acid influenza A virus protein with proapoptotic properties, PB1-F2, has been reported that originates from an alternative reading frame in the PB1 polymerase gene and is encoded in most known human influenza A virus isolat
Autor:
Mally Dori, Anat Nir, Shmuel Tuvia, Daniel N. Taglicht, Mordechai Koskas, Iris Alchanati, Oshrat Propheta-Meiran, Dalit Konforty, Haim Moskowitz, Revital Mandil-Levin, Uwe Tessmer, Iris Alroy, Yuval Reiss, Elanite Caspi-Bachar, Shenhav Cohen, Liora Yaar, Haim Barr, Tsvika Greener, Omri Erez, Alin Sela-Brown, Daphna Gordon, Danny Ben-Avraham, Ulrich S. Schubert, Vivian Bicoviski, Orit Levius
Publikováno v:
Proceedings of the National Academy of Sciences. 102:1478-1483
HIV type 1 (HIV-1) was shown to assemble either at the plasma membrane or in the membrane of late endosomes. Now, we report an essential role for human ubiquitin ligase POSH (Plenty of SH3s; hPOSH), a trans-Golgi network-associated protein, in the ta
Publikováno v:
Journal of Peptide Science. 11:481-490
Recently the discovery of a novel 87 amino acid influenza A virus (IAV) protein, named PB1-F2, has been reported that originates from an alternative reading frame in the PB1 polymerase gene and is encoded in most of the known human IAV isolates. Usin
Publikováno v:
Journal of Biological Chemistry. 278:43188-43201
The 96-residue human immunodeficiency virus (HIV) accessory protein Vpr serves manifold functions in the retroviral life cycle including augmentation of viral replication in non-dividing host cells, induction of G2 cell cycle arrest, and modulation o
Autor:
Ulrich Schubert, Kerstin Zander, Jason Neidleman, Uwe Tessmer, Michael P. Sherman, Evelyn Schubert, Victor Wray, Karsten Bruns, Jeremy Luban, Warner C. Greene, Alexander T. Prechtel, Peter Henklein
Publikováno v:
Journal of Biological Chemistry. 278:43202-43213
Viral protein R (Vpr) of human immunodeficiency virus, type 1 (HIV-1) is the major virion-associated accessory protein that affects a number of biological functions in the retroviral life cycle, including promotion of the transport of the preintegrat
Autor:
Uwe Tessmer, Jeffrey B. Kopp, Warner C. Greene, Karsten Bruns, Peter Henklein, Ulrich Schubert, Michael P. Sherman, Kai Licha, Victor Wray, Carlos M. C. de Noronha
Publikováno v:
Journal of Biological Chemistry. 275:32016-32026
Human immunodeficiency virus (HIV) Vpr contributes to nuclear import of the viral pre-integration complex and induces G(2) cell cycle arrest. We describe the production of synthetic Vpr that permitted the first studies on the structure and folding of
Publikováno v:
Scopus-Elsevier
Aspartic proteinases share a conserved network of hydrogen bonds (termed "fireman's grip"), which involves the hydroxyl groups of two threonine residues in the active site Asp-Thr-Gly triplets (Thr26 in the case of human immunodeficiency virus type 1
Publikováno v:
Cell Biology International. 22:563-574
Following injection into sublethally irradiated DBA/2 or BALB/c mice, factor-dependent FDC-P1 cells undergo leukemic transformation due to oncogene activation by insertion of intracisternal A-particle (IAP) genetic elements. Similar events are observ