Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Uwe Schedler"'
Autor:
Carsten Schmidt, Anne Kammel, Julian A. Tanner, Andrew B. Kinghorn, Muhammad Moman Khan, Werner Lehmann, Marcus Menger, Uwe Schedler, Peter Schierack, Stefan Rödiger
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract For improving aptamer-ligand binding we have developed a screening system that defines optimal binding buffer composition. Using multiplex assays, one buffer system is needed which guarantees the specific binding of all aptamers. We investig
Externí odkaz:
https://doaj.org/article/88e2442d75234fd1b5a56c6b7976df8d
Autor:
Franziska Dinter, Thomas Thiehle, Uwe Schedler, Werner Lehmann, Peter Schierack, Stefan Rödiger
BackgroundLipids and amphiphilic molecules are ubiquitous and play a central role in cell signalling, cell membrane structure, and lipid transport in the human body. However, they also appear in many diseases such as atherosclerosis, cardiovascular d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4cfb08659eafd17539f7de085672427
https://doi.org/10.1101/2023.01.10.523433
https://doi.org/10.1101/2023.01.10.523433
An in situ streptavidin‐encapsulated hydrogel based on dendritic polyglycerol (dPG) which is functionalized with either an acrylate, allyl or acrylamide group and dithiolated polyethylene glycol (PEG) is constructed via a thiol‐click chemistry ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7fb576926e8534bb2f3f2ebfe982a08
Autor:
Peter Schierack, Thomas Thiele, Uwe Schedler, Franziska Werner, Carsten K. Schmidt, Heike Borcherding, Stefan Rödiger, Dirk Roggenbuck
Publikováno v:
Analytical biochemistry. 633
Rheumatoid arthritis (RA) belongs to the most often occurring autoimmune diseases in the world. For serological diagnosis, IgM auto-antibodies directed against the Fc portion of IgG referred to as rheumatoid factor are used as biomarkers. The autoant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcdf101ae88da7f0aa6d6ae94c88cbb9
https://pubmed.ncbi.nlm.nih.gov/34555369
https://pubmed.ncbi.nlm.nih.gov/34555369
Autor:
Uwe Schedler, Thomas Thiele, Heike Borcherding, Bastian Rühle, Ute Resch-Genger, Alexander Roloff, Nithiya Nirmalananthan-Budau
Publikováno v:
Analytical Chemistry. 91:8827-8834
Aldehyde moieties on 2D-supports or micro- and nanoparticles can function as anchor groups for the attachment of biomolecules or as reversible binding sites for proteins on cell surfaces. The use of aldehyde-based materials in bioanalytical and medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9078ea20240ef2e87dc46c88f0e6a148
https://doi.org/10.1021/acs.analchem.8b05515
https://doi.org/10.1021/acs.analchem.8b05515
Publikováno v:
Biomacromolecules. 19:4207-4218
Thermoresponsive brushes based on linear poly(glycidyl ether)s (PGEs) have already shown to be functional coatings for cell sheet fabrication. In here, we introduce a method to functionalize polystyrene (PS) tissue culture substrates with thermorespo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06334258d1aa762bb31a81957d02175
https://doi.org/10.1021/acs.biomac.8b00933
https://doi.org/10.1021/acs.biomac.8b00933
Publikováno v:
The Journal of Physical Chemistry C. 122:12782-12791
Dye-stained micrometer-sized polymer beads are important tools in the life sciences with applications in biomedical, biochemical, and clinical research. Here, bead-based assays are increasingly used, for example, in DNA sequencing and the detection o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c9f5741fadfae0c9c2d4e15248a1ec8
https://doi.org/10.1021/acs.jpcc.8b02546
https://doi.org/10.1021/acs.jpcc.8b02546
Publikováno v:
ACS Applied Materials & Interfaces. 10:11382-11390
Both noncovalent and covalent encapsulations of active biomolecules, for example, proteins and oligonucleotides, for a new biosensor matrix in an in situ bioorthogonal hydrogel formation via a strain-promoted azide-alkyne cycloaddition reaction were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdd0ba85f8b03b7ea796578718d4177
https://doi.org/10.1021/acsami.8b01860
https://doi.org/10.1021/acsami.8b01860
Publikováno v:
Analytical chemistry. 91(13)
Multiplex detection techniques are emerging within the fields of life science research and medical diagnostics where it is mandatory to analyze a great number of molecules. The detection techniques need to be highly efficient but often involve compli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6b4f6ada7451e7c971e63742780430
https://pubmed.ncbi.nlm.nih.gov/31247713
https://pubmed.ncbi.nlm.nih.gov/31247713
Publikováno v:
Advanced Healthcare Materials. 10:2100062
Hydrogels play an important role in the field of biomedical research and diagnostic medicine. They are emerging as a powerful tool in the context of bioanalytical assays and biosensing. In this context, this review gives an overview of different hydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9801b50a12dbcc4ff20187383a00502
https://doi.org/10.1002/adhm.202100062
https://doi.org/10.1002/adhm.202100062