Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Uwe Meya"'
Autor:
Estefania Traver, Laura Rodríguez‐Pascau, Uwe Meya, Guillem Pina, Silvia Pascual, Sonia Poli, David Eckland, Jeroen van deWetering, Alice Ke, Andreas Lindauer, Marc Martinell, Pilar Pizcueta
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 6, Pp 982-993 (2024)
Abstract Leriglitazone is a unique peroxisome proliferator‐activated receptor‐gamma (PPARγ) agonist that crosses the blood–brain barrier in humans and clinical trials have shown evidence of efficacy in neurodegenerative diseases. At clinical d
Externí odkaz:
https://doaj.org/article/4ec4dd226eab49efa5b76906dd46a712
Autor:
Wolfgang Köhler, Marc Engelen, Florian Eichler, Robin Lachmann, Ali Fatemi, Jacinda Sampson, Ettore Salsano, Josep Gamez, Maria Judit Molnar, Sílvia Pascual, Maria Rovira, Anna Vilà, Guillem Pina, Itziar Martín-Ugarte, Adriana Mantilla, Pilar Pizcueta, Laura Rodríguez-Pascau, Estefania Traver, Anna Vilalta, María Pascual, Marc Martinell, Uwe Meya, Fanny Mochel, Eavan Mc Govern, Elise Yazbeck, Magali Barbier, Marie-Pierre Luton, Françoise Pousset, Jean-Yves Hogrel, Isaac Adanyeguh, Florian Then Bergh, Caroline Bergner, Astrid Unterlauft, Hannes Roicke, Karl-Titus Hoffmann, Cordula Scherlach, Andrea Kalb, Bianca Meilick, Mandy Reuschel, Silvia Fenu, Elena Mauro, Elaine Murphy, Gauri Krishna, Tiggy Beyene, Alba Sierra, Sara Quiñoa, Anna Belen Canovas, Zoltan Grosz, Báthori Györgyi, S.I. van de Stadt, I.C. Huffnagel, W.J.C. van Ballegoij, M.M.C. Voermans, Reza Seyedsadjadi, Camille Corre, Neha Godbole, Natalie Rose Grant, Claudia Maria Brito Pires, Melissa Trovato, Nancy Yeh, Jordan Goodman, Jennifer Keller, Chris Joseph, Keith Van Haren, Sarada Sakamuri, Tina Duong, Lila Perrone, Stephanie Tran, Sally Dunaway Young, Syed Hashmi
Publikováno v:
The Lancet Neurology, 22(2), 127-136. Lancet Publishing Group
Background: Adult patients with adrenoleukodystrophy have a poor prognosis owing to development of adrenomyeloneuropathy. Additionally, a large proportion of patients with adrenomyeloneuropathy develop life-threatening progressive cerebral adrenoleuk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb8695c85f230bdb0e4f78481480d58
https://pure.amc.nl/en/publications/safety-and-efficacy-of-leriglitazone-for-preventing-disease-progression-in-men-with-adrenomyeloneuropathy-advance(6d25a248-5b0d-4f76-b918-9f438ca0dcf9).html
https://pure.amc.nl/en/publications/safety-and-efficacy-of-leriglitazone-for-preventing-disease-progression-in-men-with-adrenomyeloneuropathy-advance(6d25a248-5b0d-4f76-b918-9f438ca0dcf9).html
Autor:
Massimo Pandolfo, Kathrin Reetz, Alejandra Darling, Francisco Javier Rodriguez de Rivera, Pierre-Gilles Henry, James Joers, Christophe Lenglet, Isaac Adanyeguh, Dinesh Deelchand, Fanny Mochel, Françoise Pousset, Sílvia Pascual, Delphine Van den Eede, Itziar Martin-Ugarte, Anna Vilà-Brau, Adriana Mantilla, María Pascual, Marc Martinell, Uwe Meya, Alexandra Durr
Publikováno v:
Neurology : official journal of the American Academy of Neurology / Genetics 8(6), e200034 (2022). doi:10.1212/NXG.0000000000200034
Neurology : official journal of the American Academy of Neurology / Genetics 8(6), e200034 (2022). doi:10.1212/NXG.0000000000200034
Published by [Verlag nicht ermittelbar], Minneapolis, Minn.
Published by [Verlag nicht ermittelbar], Minneapolis, Minn.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eded2594bcca3679fd58e99ce8041e20
https://pubmed.ncbi.nlm.nih.gov/36524101
https://pubmed.ncbi.nlm.nih.gov/36524101
Autor:
Guillem Pina, Stephan Kemp, Anna Vilalta, Marc Cerrada, Isabelle Weinhofer, Sonja Forss-Petter, Marc Martinell, Estefania Traver, Johannes Berger, Uwe Meya, Laura Rodríguez-Pascau, Silvia Pascual, Pilar Pizcueta, Patricia L. Musolino, Jan Bauer
Publikováno v:
Science Translational Medicine
Science translational medicine, 13(596):eabc0555. American Association for the Advancement of Science
Science translational medicine, 13(596):eabc0555. American Association for the Advancement of Science
X-linked adrenoleukodystrophy (X-ALD), a potentially fatal neurometabolic disorder with no effective pharmacological treatment, is characterized by clinical manifestations ranging from progressive spinal cord axonopathy [adrenomyeloneuropathy (AMN)]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0d391b4b5fc7be9719087ed337c314
https://pubmed.ncbi.nlm.nih.gov/34078742
https://pubmed.ncbi.nlm.nih.gov/34078742
Autor:
C. Warren Olanow, Chris Resburg, Mark F. Lew, Any Docu-Axelerad, Olexandr Kozyolkin, Emmanuelle Pourcher, Stephen Bandak, Ann C. Neale, Robert A. Hauser, Karl Kieburtz, Christopher Kenney, Uwe Meya
Publikováno v:
The Lancet Neurology. 13:767-776
Summary Background Many patients with Parkinson's disease have motor fluctuations despite treatment with available drugs. Tozadenant (SYN115) is an oral, selective adenosine A 2A receptor antagonist that improves motor function in animal models of Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db59daffa937519348f52c7b8109bd81
https://doi.org/10.1016/s1474-4422(14)70148-6
https://doi.org/10.1016/s1474-4422(14)70148-6
Publikováno v:
Journal of Neurology. 229:91-96
Lesions at the volar aspect of the forearm may lead to isolated paralysis of the anterior interosseous nerve, which is a purely motor branch of the median nerve. The same syndrome may result from circumscribed damage at the level of the upper arm. Tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa899d8373703fd56cc905b9bb48247f
https://doi.org/10.1007/bf00313447
https://doi.org/10.1007/bf00313447