Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Uwe Marquardt"'
Autor:
Simon Johannes Gairing, Chiara Mangini, Lisa Zarantonello, Elise Jonasson, Henrike Dobbermann, Philippe Sultanik, Peter Robert Galle, Joachim Labenz, Dominique Thabut, Jens Uwe Marquardt, Patricia P. Bloom, Mette Munk Lauridsen, Sara Montagnese, Christian Labenz
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101104- (2024)
Background & Aims: Data on the association between proton pump inhibitor (PPI) use and hepatic encephalopathy (HE) are conflicting, and data from multicentre studies are scarce. The aim of this study was to dissect the potential association between P
Externí odkaz:
https://doaj.org/article/0a4b191f35084e7bbef0e7add8959781
Autor:
Hendrik Ungefroren, Juliane von der Ohe, Rüdiger Braun, Yola Gätje, Olha Lapshyna, Jörg Schrader, Hendrik Lehnert, Jens-Uwe Marquardt, Björn Konukiewitz, Ralf Hass
Publikováno v:
Cells, Vol 13, Iss 23, p 2010 (2024)
Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis, due in part to early invasion and metastasis, which in turn involves epithelial–mesenchymal transition (EMT) of the cancer cells. Prompted by the discovery that two PDAC cell
Externí odkaz:
https://doaj.org/article/5cb219602fa147a3aa6e525c78857a80
Autor:
Wafaa Abumustafa, Darko Castven, Fatemeh Saheb Sharif-Askari, Batoul Abi Zamer, Mawieh Hamad, Jens-Uwe Marquardt, Jibran Sualeh Muhammad
Publikováno v:
Biology, Vol 13, Iss 4, p 216 (2024)
Protein arginine N-methyltransferase 5 (PRMT5) has been identified as a potential therapeutic target for various cancer types. However, its role in regulating the hepatocellular carcinoma (HCC) transcriptome remains poorly understood. In this study,
Externí odkaz:
https://doaj.org/article/7ed6f199d3964bc5b98456735e80f93e
Autor:
Hendrik Ungefroren, Julissa Reimann, Björn Konukiewitz, Rüdiger Braun, Ulrich F. Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 199 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer type characterized by a marked desmoplastic tumor stroma that is formed under the influence of transforming growth factor (TGF)-β. Data from mouse models of pancreatic cancer have
Externí odkaz:
https://doaj.org/article/75f8d918348c4e9f8c269ab2a220640b
Autor:
Simon Johannes Gairing, Sven Danneberg, Leonard Kaps, Michael Nagel, Eva Maria Schleicher, Charlotte Quack, Sinah Engel, Stefan Bittner, Peter Robert Galle, Jörn Markus Schattenberg, Marcus-Alexander Wörns, Felix Luessi, Jens Uwe Marquardt, Christian Labenz
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100671- (2023)
Background & Aims: Blood biomarkers facilitating the diagnosis of covert hepatic encephalopathy (CHE) in patients with cirrhosis are lacking. Astrocyte swelling is a major component of hepatic encephalopathy. Thus, we hypothesised that glial fibrilla
Externí odkaz:
https://doaj.org/article/701ec0faf173408db3245c6365e267e6
Autor:
Felix Thol, Simon Johannes Gairing, Carolin Czauderna, Thomas Thomaidis, Thomas Gamstätter, Yvonne Huber, Johanna Vollmar, Johanna Lorenz, Maurice Michel, Fabian Bartsch, Lukas Müller, Roman Kloeckner, Peter Robert Galle, Marcus-Alexander Wörns, Jens Uwe Marquardt, Markus Moehler, Arndt Weinmann, Friedrich Foerster
Publikováno v:
JHEP Reports, Vol 4, Iss 3, Pp 100417- (2022)
Background & Aims: Advanced biliary tract cancer (ABTC) is associated with a poor prognosis. Real-world data on the outcome of patients with ABTC undergoing sequential chemotherapies remain scarce, and little is known about treatment options beyond t
Externí odkaz:
https://doaj.org/article/ca54cc67fe5d403f87475984aa7900e7
Autor:
Rüdiger Braun, Olha Lapshyna, Jessica Watzelt, Maren Drenckhan, Axel Künstner, Benedikt Färber, Ahmed Ahmed Mohammed Hael, Louisa Bolm, Kim Christin Honselmann, Björn Konukiewitz, Darko Castven, Malte Spielmann, Sivahari Prasad Gorantla, Hauke Busch, Jens-Uwe Marquardt, Tobias Keck, Ulrich Friedrich Wellner, Hendrik Ungefroren
Publikováno v:
Cells, Vol 12, Iss 4, p 587 (2023)
The prognosis of pancreatic ductal adenocarcinoma (PDAC) is exceedingly poor. Although surgical resection is the only curative treatment option, multimodal treatment is of the utmost importance, as only about 20% of tumors are primarily resectable at
Externí odkaz:
https://doaj.org/article/217dd6f9a824404c944446bfa3c6760d
Autor:
Hendrik Ungefroren, Rüdiger Braun, Olha Lapshyna, Björn Konukiewitz, Ulrich F. Wellner, Hendrik Lehnert, Jens-Uwe Marquardt
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2640 (2022)
Pancreatic ductal adenocarcinoma (PDAC) cells are known for their high invasive/metastatic potential, which is regulated in part by the transforming growth factor β1 (TGFβ1). The involvement of at least two type I receptors, ALK5 and ALK2, that tra
Externí odkaz:
https://doaj.org/article/08893937907d4b909e6c3d7605ba1f5d
Autor:
Svenja Meyhöfer, Armin Steffen, Kirstin Plötze-Martin, Christian Lange, Jens-Uwe Marquardt, Karl-Ludwig Bruchhage, Sebastian M. Meyhöfer, Ralph Pries
Publikováno v:
ImmunoHorizons. 7:191-199
Obesity is a dramatically increasing disease, accompanied with comorbidities such as cardiovascular disease and obstructive sleep apnea syndrome (OSAS). Both obesity and OSAS per se are associated with systemic inflammation. However, the multifactori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8699b8cf86975ce7596a77298c25bc6c
https://doi.org/10.4049/immunohorizons.2300009
https://doi.org/10.4049/immunohorizons.2300009
Publikováno v:
Gastroenterologie up2date. 18:369-388
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::466b9cc96412c6fd2e76f14eb85d75a1
https://doi.org/10.1055/a-1810-5097
https://doi.org/10.1055/a-1810-5097