Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Uwe Lipke"'
Publikováno v:
European journal of pharmaceutics and biopharmaceutics, 130:22-29
Commercially available, uncoated elastomeric closures were examined in regard to a potential contribution of extracted compounds from the rubber stoppers to protein aggregation under worst-case conditions. All rubber stoppers were confirmed to comply
Autor:
Sonja Molin, Uwe Lipke, Vera Mahler, Claudia Pföhler, Kristine Breuer, Cornelia Lipperheide, H. Löffler, Axel Schnuch, Thomas Zapf, H. Schwantes, Heinrich Dickel, Regina Treudler
Publikováno v:
Allergy. 70:220-226
Background Aluminium tubes for pharmaceutical use are internally lacquered with epoxy resins (ER) based on bisphenol A diglycidyl ether (BADGE). Recently, it was shown that remnants of ER polymerization like BADGE are extractable from epoxy-based coa
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 101
To study the impact of different semi-solid dosage form components on the leaching of Bisphenol A (BPA) and Bisphenol A diglycidyl ether (BADGE) from the epoxy resin-based inner lacquer of aluminium tubes, the tubes were filled with different matrix
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 70(3)
The objective of this study was to determine to what extent bisphenol A (BPA), bisphenol A diglycidyl ether (BADGE) and its derivatives are extractable from epoxy-based coatings of aluminium tubes for pharmaceutical use and to monitor their leaching