Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Uwe Knippschild"'
Autor:
Ann-Kathrin Kissmann, Frederike Paß, Hans-Maximilian Ruzicka, Isabel Dorst, Kai R. Stieger, Tanja Weil, Adrian Gihring, Leonard Elad, Uwe Knippschild, Frank Rosenau
Publikováno v:
Women, Vol 4, Iss 1, Pp 86-104 (2024)
The global increase in obesity carries inherent health implications, with an increased BMI being a known risk factor for diseases such as type 2 diabetes, cardiovascular diseases, or different cancer types. The long-term effectiveness of diet therapy
Externí odkaz:
https://doaj.org/article/a03ffef5f50a4dda860b7cf6ab5c65d0
Autor:
Anna Worthmann, Julius Ridder, Sharlaine Y. L. Piel, Ioannis Evangelakos, Melina Musfeldt, Hannah Voß, Marie O’Farrell, Alexander W. Fischer, Sangeeta Adak, Monica Sundd, Hasibullah Siffeti, Friederike Haumann, Katja Kloth, Tatjana Bierhals, Markus Heine, Paul Pertzborn, Mira Pauly, Julia-Josefine Scholz, Suman Kundu, Marceline M. Fuh, Axel Neu, Klaus Tödter, Maja Hempel, Uwe Knippschild, Clay F. Semenkovich, Hartmut Schlüter, Joerg Heeren, Ludger Scheja, Christian Kubisch, Christian Schlein
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Dietary polyunsaturated fatty acids (PUFA) are increasingly recognized for their health benefits, whereas a high production of endogenous fatty acids – a process called de novo lipogenesis (DNL) - is closely linked to metabolic diseases. D
Externí odkaz:
https://doaj.org/article/d4a6b8efd8424ceaa3b39a71f53879ef
Autor:
Laura Meier, Bernd Martin Gahr, Aileen Roth, Adrian Gihring, Stefan Kirschner, Clemens Woitaske-Proske, Joana Baier, Christian Peifer, Steffen Just, Uwe Knippschild
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: The CK1 family is involved in a variety of physiological processes by regulating different signaling pathways, including the Wnt/β-catenin, the Hedgehog and the p53 signaling pathways. Mutations or dysregulation of kinases in general a
Externí odkaz:
https://doaj.org/article/77461f23611445b1bde586b3cd5612c0
Autor:
Adrian Gihring, Fabian Gärtner, Laura Mayer, Aileen Roth, Hend Abdelrasoul, Marko Kornmann, Leonard Elad, Uwe Knippschild
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionObesity is associated with low-grade chronic inflammation, altered levels of adipocytokines, and impaired regulation of gastrointestinal hormones. Secreted, these factors exert immunostimulatory functions directly influencing peripheral i
Externí odkaz:
https://doaj.org/article/492ce8d922654dfd87eefb99e512958d
Autor:
Yiting Zhang, Hu Xing, Grigory Bolotnikov, Markus Krämer, Nina Gotzmann, Uwe Knippschild, Ann-Kathrin Kissmann, Frank Rosenau
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2266 (2023)
Rikenella microfusus is an essential intestinal probiotic with great potential. The latest research shows that imbalance in the intestinal flora are related to the occurrence of various diseases, such as intestinal diseases, immune diseases, and meta
Externí odkaz:
https://doaj.org/article/e2d470343587459f99b621b51b8f5958
Autor:
Pengfei Xu, Mike-Andrew Westhoff, Amina Hadzalic, Klaus-Michael Debatin, Lukasz Winiarski, Jozef Oleksyszyn, Christian Rainer Wirtz, Uwe Knippschild, Timo Burster
Publikováno v:
ACS Omega, Vol 7, Iss 7, Pp 5929-5936 (2022)
Externí odkaz:
https://doaj.org/article/8054992f457a40bb980f1b248e750204
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/5888fd43d4b04163a4bb6fdd3d30f49b
Autor:
Aileen Roth, Annabelle Sander, Marleen Silke Oswald, Fabian Gärtner, Uwe Knippschild, Joachim Bischof
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
A main pathological event in Alzheimer’s disease is the generation of neurofibrillary tangles originating from hyperphosphorylated and subsequently aggregated tau proteins. Previous reports demonstrated the critical involvement of members of the pr
Externí odkaz:
https://doaj.org/article/159897067f224516a89832a55032243d
Autor:
Xiao Shen, Anna-Laura Kretz, Sandra Schneider, Uwe Knippschild, Doris Henne-Bruns, Marko Kornmann, Johannes Lemke, Benno Traub
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 928 (2023)
Treatment options for colorectal cancer (CRC), especially in advanced stages are still insufficient. There, the discovery of Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) was a bright spot. However, most cancers show resistanc
Externí odkaz:
https://doaj.org/article/e388087c30d642e1a34596eb6e201229
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The urgency to investigate trauma in a controlled and reproducible environment rises since multiple trauma still account for the most deaths for people under the age of 45. The most common multiple trauma include head as well as blunt thorax trauma a
Externí odkaz:
https://doaj.org/article/c00f31130dff4b26ac67cd09390836ad