Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Uwe Dressel"'
Autor:
Aimee L. Davidson, Uwe Dressel, Sarah Norris, Daffodil M. Canson, Dylan M. Glubb, Cristina Fortuno, Georgina E. Hollway, Michael T. Parsons, Miranda E. Vidgen, Oliver Holmes, Lambros T. Koufariotis, Vanessa Lakis, Conrad Leonard, Scott Wood, Qinying Xu, Amy E. McCart Reed, Hilda A. Pickett, Mohammad K. Al-Shinnag, Rachel L. Austin, Jo Burke, Elisa J. Cops, Cassandra B. Nichols, Annabel Goodwin, Marion T. Harris, Megan J. Higgins, Emilia L. Ip, Catherine Kiraly-Borri, Chiyan Lau, Julia L. Mansour, Michael W. Millward, Melissa J. Monnik, Nicholas S. Pachter, Abiramy Ragunathan, Rachel D. Susman, Sharron L. Townshend, Alison H. Trainer, Simon L. Troth, Katherine M. Tucker, Mathew J. Wallis, Maie Walsh, Rachel A. Williams, Ingrid M. Winship, Felicity Newell, Emma Tudini, John V. Pearson, Nicola K. Poplawski, Helen G. Mar Fan, Paul A. James, Amanda B. Spurdle, Nicola Waddell, Robyn L. Ward
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Many families and individuals do not meet criteria for a known hereditary cancer syndrome but display unusual clusters of cancers. These families may carry pathogenic variants in cancer predisposition genes and be at higher risk f
Externí odkaz:
https://doaj.org/article/e7517b7792c7450392b54b67bde9ca87
Autor:
Jiangling Cao, Nial R. Gursanscky, Stephen J. Fletcher, Anne Sawyer, Mehershad Wadia, Lachlan McKeough, Marek Coleman, Uwe Dressel, Christelle Taochy, Neena Mitter, Hervé Vaucheret, Bernard J. Carroll
Publikováno v:
Plant Methods, Vol 16, Iss 1, Pp 1-12 (2020)
Abstract Background Forward genetic screens are a powerful approach for identifying the genes contributing to a trait of interest. However, mutants arising in genes already known can obscure the identification of new genes contributing to the trait.
Externí odkaz:
https://doaj.org/article/89d6dbecf9734a4198a7e8fefd8e0267
Autor:
Yoland Antill, Paul A. James, Judy Kirk, Uwe Dressel, Nicola K. Poplawski, Lucinda Salmon, Nicholas Pachter, Aimee L Davidson, Sharron Townshend, Michael Gattas, Emma Tudini, Gillian Mitchell, Helen Mar Fan, Rachel Susman, Katherine M. Tucker, Robyn L. Ward, Michael Field, Ashley Crook, Alison H. Trainer, Amanda B. Spurdle, Lesley Andrews, Rebecca Harris
Publikováno v:
Journal of Medical Genetics. 58:853-858
BackgroundThe strength of evidence supporting the validity of gene-disease relationships is variable. Hereditary cancer has the additional complexity of low or moderate penetrance for some confirmed disease-associated alleles.MethodsTo promote nation
Autor:
Marek Coleman, Nial R. Gursanscky, Mehershad Wadia, Stephen J. Fletcher, Anne Sawyer, Uwe Dressel, Lachlan McKeough, Bernard J. Carroll, Christelle Taochy, Hervé Vaucheret, Jiangling Cao, Neena Mitter
Publikováno v:
Plant Methods, Vol 16, Iss 1, Pp 1-12 (2020)
Plant Methods
Plant Methods, BioMed Central, 2020, 16 (1), ⟨10.1186/s13007-020-0555-0⟩
Plant Methods
Plant Methods, BioMed Central, 2020, 16 (1), ⟨10.1186/s13007-020-0555-0⟩
Background Forward genetic screens are a powerful approach for identifying the genes contributing to a trait of interest. However, mutants arising in genes already known can obscure the identification of new genes contributing to the trait. Here, we
Publikováno v:
International Journal of Productivity and Performance Management. 67:239-259
PurposeAgency theory suggests that divergences will occur when a principal, e.g. client, and agent e.g. a project manager, interests are different in the execution of a project. The purpose of this paper is to explore if the agency theory can explain
Autor:
Bernard J. Carroll, John L. Bowman, Matthew R. Tucker, Nial R. Gursanscky, Jiangling Cao, Christelle Taochy, Neena Mitter, Stephen J. Fletcher, Anna M. G. Koltunow, Hervé Vaucheret, Uwe Dressel
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2017, 175 (3), pp.1424-1437. ⟨10.1104/pp.17.01181⟩
Plant Physiology, American Society of Plant Biologists, 2017, 175 (3), pp.1424-1437. ⟨10.1104/pp.17.01181⟩
International audience; Posttranscriptional gene silencing (PTGS) of transgenes involves abundant 21-nucleotide small interfering RNAs (siRNAs) and low-abundance 22-nucleotide siRNAs produced fromdouble-stranded RNA (dsRNA) by DCL4 and DCL2, respecti
Autor:
Kathy Briffa, Geoffrey C. Nicholson, Uwe Dressel, Jason M. Hodge, Paul A. Baldock, Peter D. O’Loughlin, Edith M. Gardiner, John A. Eisman, Sara U. K. Baker, Gethin P. Thomas
Publikováno v:
Journal of Bone and Mineral Research. 21:1618-1626
Vitamin D acts through the immature osteoblast to stimulate osteoclastogenesis. Transgenic elevation of VDR in mature osteoblasts was found to inhibit osteoclastogenesis associated with an altered OPG response. This inhibition was confined to cancell
Autor:
Christina A. Reeb, Sami Väisänen, Aria Baniahmad, Udo Moehren, Thomas W. Dunlop, Uwe Dressel, Carsten Carlberg
Publikováno v:
Nucleic Acids Research. 32:2995-3004
The Sin3 proteins are evolutionarily conserved co-repressors (CoR) that function as mediators of gene repression for a variety of transcriptional silencers. The paired amphipathic helices of Sin3A were identified and studied as protein–protein inte
Autor:
Paul R. Rohde, Patrick Lau, Tamara L. Allen, George E.O. Muscat, Jyotsna B. Pippal, Uwe Dressel
Publikováno v:
Molecular Endocrinology. 17:2477-2493
Lipid homeostasis is controlled by the peroxisome proliferator-activated receptors (PPARalpha, -beta/delta, and -gamma) that function as fatty acid-dependent DNA-binding proteins that regulate lipid metabolism. In vitro and in vivo genetic and pharma
Publikováno v:
Protein Expression and Purification. 26:462-466
We describe here an unusual phenomenon in the isolation of protein complexes from eukaryotic cells using expressed GST-fusion proteins. Protein complexes are involved in a large number of regulatory mechanisms. Therefore, the use of tagged fusion pro