Zobrazeno 1 - 10
of 439
pro vyhledávání: '"Uwe, Oelfke"'
Autor:
Rosalyne L. Westley, Sophie E. Alexander, Edmund Goodwin, Alex Dunlop, Simeon Nill, Uwe Oelfke, Helen A. McNair, Alison C. Tree
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionWe aimed to establish if stereotactic body radiotherapy to the prostate can be delivered safely using reduced clinical target volume (CTV) to planning target volume (PTV) margins on the 1.5T MR-Linac (MRL) (Elekta, Stockholm, Sweden), in
Externí odkaz:
https://doaj.org/article/0f40f34073ce4e5c9118a40a4c25ca33
Autor:
Vesela Koteva, Björn Eiben, Alex Dunlop, Amit Gupta, Tarun Gangil, Kee Howe Wong, Sebastiaan Breedveld, Simeon Nill, Kevin Harrington, Uwe Oelfke
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMR-Linac allows for daily online treatment adaptation to the observed geometry of tumor targets and organs at risk (OARs). Manual delineation for head and neck cancer (HNC) patients takes 45-75 minutes, making it unsuitable for online adapt
Externí odkaz:
https://doaj.org/article/4ceba39fc7a249d68c40ade394215d04
Autor:
Kobika Sritharan, Alex Dunlop, Jonathan Mohajer, Gillian Adair-Smith, Helen Barnes, Douglas Brand, Emily Greenlay, Adham Hijab, Uwe Oelfke, Angela Pathmanathan, Adam Mitchell, Julia Murray, Simeon Nill, Chris Parker, Nora Sundahl, Alison C. Tree
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 37, Iss , Pp 25-32 (2022)
Background: The prostate demonstrates inter- and intra- fractional changes and thus adaptive radiotherapy would be required to ensure optimal coverage. Daily adaptive radiotherapy for MRI-guided radiotherapy can be both time and resource intensive wh
Externí odkaz:
https://doaj.org/article/d9325642b59a408e9474e6c72b63a697
Autor:
Bastien Lecoeur, Marco Barbone, Jessica Gough, Uwe Oelfke, Wayne Luk, Georgi Gaydadjiev, Andreas Wetscherek
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 27, Iss , Pp 100484- (2023)
Background and purpose: Physiological motion impacts the dose delivered to tumours and vital organs in external beam radiotherapy and particularly in particle therapy. The excellent soft-tissue demarcation of 4D magnetic resonance imaging (4D-MRI) co
Externí odkaz:
https://doaj.org/article/dbb7e8c0102743dd8cb22445868b5d13
Autor:
Joan Chick, Sophie Alexander, Trina Herbert, Robert Huddart, Manasi Ingle, Adam Mitchell, Simeon Nill, Uwe Oelfke, Alex Dunlop, Shaista Hafeez
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 27, Iss , Pp 100481- (2023)
Hybrid systems that combine Magnetic Resonance Imaging (MRI) and linear accelerators are available clinically to guide and adapt radiotherapy. Vendor-approved MRI sequences are provided, however alternative sequences may offer advantages. The aim of
Externí odkaz:
https://doaj.org/article/cbf55297621144559b90ac735e5ed634
Autor:
Amit Gupta, Alex Dunlop, Adam Mitchell, Dualta McQuaid, Simeon Nill, Helen Barnes, Kate Newbold, Chris Nutting, Shreerang Bhide, Uwe Oelfke, Kevin Joseph Harrington, Kee Howe Wong
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 32, Iss , Pp 48-51 (2022)
Introduction: The Elekta Unity MR-Linac (MRL) has enabled adaptive radiotherapy (ART) for patients with head and neck cancers (HNC). Adapt-To-Shape-Lite (ATS-Lite) is a novel Adapt-to-Shape strategy that provides ART without requiring daily clinician
Externí odkaz:
https://doaj.org/article/2cec4f7681cd44ad930a1db2dc15d89a
Autor:
Imogen Thrussell, Jessica M. Winfield, Matthew R. Orton, Aisha B. Miah, Shane H. Zaidi, Amani Arthur, Khin Thway, Dirk C. Strauss, David J. Collins, Dow-Mu Koh, Uwe Oelfke, Paul H. Huang, James P. B. O’Connor, Christina Messiou, Matthew D. Blackledge
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundSize-based assessments are inaccurate indicators of tumor response in soft-tissue sarcoma (STS), motivating the requirement for new response imaging biomarkers for this rare and heterogeneous disease. In this study, we assess the test–ret
Externí odkaz:
https://doaj.org/article/a7683e70ad334fd4b541a7916f588e86
Autor:
Jonathan Mohajer, Alex Dunlop, Adam Mitchell, Edmund Goodwin, Simeon Nill, Uwe Oelfke, Alison Tree
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 26, Iss , Pp 1-7 (2021)
The drive towards hypofractionated prostate radiotherapy is motivated by a low alpha/beta ratio for prostate cancer (1 to 3 Gy) compared to surrounding organs at risk, implying an improved therapeutic ratio with increasing dose per fraction. Early ev
Externí odkaz:
https://doaj.org/article/1c13ffa3597e4b4bb472fe958c698a66
Autor:
Alex Dunlop, Adam Mitchell, Alison Tree, Helen Barnes, Lorna Bower, Joan Chick, Edmund Goodwin, Trina Herbert, Rebekah Lawes, Helen McNair, Dualta McQuaid, Jonathan Mohajer, Rahul Nilawar, Angela Pathmanathan, Gillian Smith, Ian Hanson, Simeon Nill, Uwe Oelfke
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 23, Iss , Pp 35-42 (2020)
Introduction: MR-guided adapted radiotherapy (MRgART) using a high field MR-linac has recently become available. We report the estimated delivered fractional dose of the first five prostate cancer patients treated at our centre using MRgART and compa
Externí odkaz:
https://doaj.org/article/d2dcf0ae6f334918960d0c5717df2801
Autor:
Oliver J. Gurney-Champion, Jennifer P. Kieselmann, Kee H. Wong, Brian Ng-Cheng-Hin, Kevin Harrington, Uwe Oelfke
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 15, Iss , Pp 1-7 (2020)
Background and purpose: Retrieving quantitative parameters from magnetic resonance imaging (MRI), e.g. for early assessment of radiotherapy treatment response, necessitates contouring regions of interest, which is time-consuming and prone to errors.
Externí odkaz:
https://doaj.org/article/dbbf07add3f543d09e80a399cf49de65