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Akademický článek
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Publikováno v:
PLoS Computational Biology, Vol 15, Iss 8, p e1007252 (2019)
Massively parallel RNA sequencing (RNA-seq) in combination with metabolic labeling has become the de facto standard approach to study alterations in RNA transcription, processing or decay. Regardless of advances in the experimental protocols and tech
Externí odkaz:
https://doaj.org/article/769aff850b114c568c48865fe15a62a6
Autor:
Moritz Jakab, Ki Hong Lee, Alexey Uvarovskii, Svetlana Ovchinnikova, Shubhada R Kulkarni, Till Rostalski, Simon Anders, Hellmut G Augustin
During metastasis, cancer cells hijack blood vessels and travel via the circulation to colonize distant sites1,2. Due to the rarity of these events, the immediate cell fate decisions of arrested circulating tumour cells (aCTC) are poorly understood a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93db14432f2c2fe64809622d9ab5f429
https://doi.org/10.1101/2022.06.18.496680
https://doi.org/10.1101/2022.06.18.496680
Autor:
Carsten Sticht, Simon Anders, Gergana Dobreva, Alexey Uvarovskii, Manuel Winkler, Sina Wietje Kürschner, Michelle Neßling, Sergij Goerdt, Hiltrud Schönhaber, Theresa Staniczek, Arthur Mathes, Carolin Mogler, Daniel Hartmann, Julio Cordero, Christian Schmid, Philipp-Sebastian Koch, Linda Kessler, Cyrill Géraud, Guido von Figura, Kai Schledzewski, Xue-jun Zhang
Publikováno v:
Journal of Hepatology. 74:380-393
Background & Aims Angiocrine signaling by liver sinusoidal endothelial cells (LSECs) regulates hepatic functions such as growth, metabolic maturation, and regeneration. Recently, we identified GATA4 as the master regulator of LSEC specification durin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771b6fb2d532be449fafa60eba9cf31f
https://doi.org/10.1016/j.jhep.2020.08.033
https://doi.org/10.1016/j.jhep.2020.08.033
Autor:
Uvarovskii, Alexey1,2 alexey.mipt@gmail.com, Naarmann-de Vries, Isabel S.3, Dieterich, Christoph1,2 christoph.dieterich@uni-heidelberg.de
Publikováno v:
PLoS Computational Biology. 8/7/2019, Vol. 15 Issue 8, p1-22. 22p. 1 Diagram, 5 Graphs.
Autor:
Hyatt Balke-Want, Alexey Uvarovskii, Carsten Müller-Tidow, Jan-Philipp Mallm, Sophie Rabe, Karsten Rippe, Martina Seiffert, Simon Anders, Stefan Fröhling, Matthias Schlesner, Wolfgang Huber, Thorsten Zenz, Tobias Roider, Benedikt Brors, Sascha Dietrich, Gunhild Mechtersheimer, Nima Abedpour, Marie Bordas, Felix Frauhammer, Julian Seufert, Peter-Martin Bruch, Benjamin Goeppert, Marta Stolarczyk, Michael Hundemer, Björn Chapuy, Martin Pfeifer
Tumor heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is well-known to affect the efficacy of anti-cancer drugs, most personalized treatment approaches do not account for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d462f91fac8845b14dcba1be46b621
Akademický článek
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Akademický článek
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Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 15, Iss 8, p e1007252 (2019)
PLoS Computational Biology 15(8), e1007252 (2019). doi:10.1371/journal.pcbi.1007252
PLoS Computational Biology, Vol 15, Iss 8, p e1007252 (2019)
PLoS Computational Biology 15(8), e1007252 (2019). doi:10.1371/journal.pcbi.1007252
Massively parallel RNA sequencing (RNA-seq) in combination with metabolic labeling has become the de facto standard approach to study alterations in RNA transcription, processing or decay. Regardless of advances in the experimental protocols and tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61d33f299c0331db7d69cd98e6658b3
http://europepmc.org/articles/PMC6699717
http://europepmc.org/articles/PMC6699717
Autor:
Benedikt Brors, Nima Abedpour, Peter-Martin Bruch, Benjamin Goeppert, Hyatt Balke-Want, Carsten Müller-Tidow, Jan-Philipp Mallm, Julian Seufert, Marta Stolarczyk, Stefan Fröhling, Sascha Dietrich, Karsten Rippe, Alexey Uvarovskii, Marie Bordas, Matthias Schlesner, Gunhild Mechtersheimer, Simon Anders, Sophie A. Herbst, Tobias Roider, Martin Pfeifer, Wolfgang Huber, Felix Frauhammer, Thorsten Zenz, Michael Hundemer, Martina Seiffert, Björn Chapuy
Publikováno v:
Nature cell biology. 22(7)
Tumour heterogeneity encompasses both the malignant cells and their microenvironment. While heterogeneity between individual patients is known to affect the efficacy of cancer therapy, most personalized treatment approaches do not account for intratu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af0726b670852c86b97ba5113d06781
https://pubmed.ncbi.nlm.nih.gov/32541878
https://pubmed.ncbi.nlm.nih.gov/32541878