Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Utz Fischer"'
Autor:
Abdolhossein Zare, Saeede Salehi, Jakob Bader, Cornelius Schneider, Utz Fischer, Alexander Veh, Panagiota Arampatzi, Matthias Mann, Michael Briese, Michael Sendtner
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Motoneurons critically depend on precise spatial and temporal control of translation for axon growth and the establishment and maintenance of neuromuscular connections. While defects in local translation have been implicated in the pathogene
Externí odkaz:
https://doaj.org/article/cc2d92103f774896b91e6efd968bdcaf
Autor:
Simon Betzold, Johannes Düreth, Marco Dusel, Monika Emmerling, Antonina Bieganowska, Jürgen Ohmer, Utz Fischer, Sven Höfling, Sebastian Klembt
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Artificial 1D and 2D lattices have emerged as a powerful platform for the emulation of lattice Hamiltonians, the fundamental study of collective many‐body effects, and phenomena arising from non‐trivial topology. Exciton‐polaritons, bo
Externí odkaz:
https://doaj.org/article/cb553ff91f85465e835de23030b237cb
Autor:
Wim P Burmeister, Laetitia Boutin, Aurelia C Balestra, Henri Gröger, Allison Ballandras-Colas, Stephanie Hutin, Christian Kraft, Clemens Grimm, Bettina Böttcher, Utz Fischer, Nicolas Tarbouriech, Frédéric Iseni
Publikováno v:
PLoS Pathogens, Vol 20, Iss 5, p e1011652 (2024)
The year 2022 was marked by the mpox outbreak caused by the human monkeypox virus (MPXV), which is approximately 98% identical to the vaccinia virus (VACV) at the sequence level with regard to the proteins involved in DNA replication. We present the
Externí odkaz:
https://doaj.org/article/eec1222b7c4c413a8982364e3adc44c6
Autor:
Archana Bairavasundaram Prusty, Anja Hirmer, Julieth Andrea Sierra-Delgado, Hannes Huber, Ulf-Peter Guenther, Andreas Schlosser, Olexandr Dybkov, Ezgi Yildirim, Henning Urlaub, Kathrin C. Meyer, Sibylle Jablonka, Florian Erhard, Utz Fischer
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113802- (2024)
Summary: RNA helicases constitute a large protein family implicated in cellular RNA homeostasis and disease development. Here, we show that the RNA helicase IGHMBP2, linked to the neuromuscular disorder spinal muscular atrophy with respiratory distre
Externí odkaz:
https://doaj.org/article/40bcb37068314b4d873280bbd198a9d7
Autor:
Josef Pánek, Adriana Roithová, Nenad Radivojević, Michal Sýkora, Archana Bairavasundaram Prusty, Nicholas Huston, Han Wan, Anna Marie Pyle, Utz Fischer, David Staněk
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Spliceosomal snRNPs are multicomponent particles that undergo a complex maturation pathway. Human Sm-class snRNAs are generated as 3′-end extended precursors, which are exported to the cytoplasm and assembled together with Sm proteins into
Externí odkaz:
https://doaj.org/article/b0a36e6461ad4fc185cfe84b162ad07f
Autor:
Saeede Salehi, Abdolhossein Zare, Gianluca Prezza, Jakob Bader, Cornelius Schneider, Utz Fischer, Felix Meissner, Matthias Mann, Michael Briese, Michael Sendtner
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating alternative splicing programs in the nucleus. Such programs contribute to axonogenesis by adjusting the levels of protein isoforms involved in axon growt
Externí odkaz:
https://doaj.org/article/7a5c867c7f5646f78c1ebd85d15dd934
Autor:
Maria Körner, Susanne R Meyer, Gabriella Marincola, Maximilian J Kern, Clemens Grimm, Christina Schuelein-Voelk, Utz Fischer, Kay Hofmann, Alexander Buchberger
Publikováno v:
eLife, Vol 12 (2023)
The ATPase p97 (also known as VCP, Cdc48) has crucial functions in a variety of important cellular processes such as protein quality control, organellar homeostasis, and DNA damage repair, and its de-regulation is linked to neuromuscular diseases and
Externí odkaz:
https://doaj.org/article/088885aee7b845c49c72985154a87b7b
Autor:
Ilaria Mannucci, Nghi D. P. Dang, Hannes Huber, Jaclyn B. Murry, Jeff Abramson, Thorsten Althoff, Siddharth Banka, Gareth Baynam, David Bearden, Ana Beleza-Meireles, Paul J. Benke, Siren Berland, Tatjana Bierhals, Frederic Bilan, Laurence A. Bindoff, Geir Julius Braathen, Øyvind L. Busk, Jirat Chenbhanich, Jonas Denecke, Luis F. Escobar, Caroline Estes, Julie Fleischer, Daniel Groepper, Charlotte A. Haaxma, Maja Hempel, Yolanda Holler-Managan, Gunnar Houge, Adam Jackson, Laura Kellogg, Boris Keren, Catherine Kiraly-Borri, Cornelia Kraus, Christian Kubisch, Gwenael Le Guyader, Ulf W. Ljungblad, Leslie Manace Brenman, Julian A. Martinez-Agosto, Matthew Might, David T. Miller, Kelly Q. Minks, Billur Moghaddam, Caroline Nava, Stanley F. Nelson, John M. Parant, Trine Prescott, Farrah Rajabi, Hanitra Randrianaivo, Simone F. Reiter, Janneke Schuurs-Hoeijmakers, Perry B. Shieh, Anne Slavotinek, Sarah Smithson, Alexander P. A. Stegmann, Kinga Tomczak, Kristian Tveten, Jun Wang, Jordan H. Whitlock, Christiane Zweier, Kirsty McWalter, Jane Juusola, Fabiola Quintero-Rivera, Utz Fischer, Nan Cher Yeo, Hans-Jürgen Kreienkamp, Davor Lessel
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-19 (2021)
Abstract Background We aimed to define the clinical and variant spectrum and to provide novel molecular insights into the DHX30-associated neurodevelopmental disorder. Methods Clinical and genetic data from affected individuals were collected through
Externí odkaz:
https://doaj.org/article/c447334b912746929ee920eb4139f48f
Autor:
Changhe Ji, Jakob Bader, Pradhipa Ramanathan, Luisa Hennlein, Felix Meissner, Sibylle Jablonka, Matthias Mann, Utz Fischer, Michael Sendtner, Michael Briese
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The noncoding RNA 7SK controls the transcription of mRNAs. Here, the authors show that the 7SK complex interacts with the Smn complex, suggesting crosstalk between transcription and snRNP assembly.
Externí odkaz:
https://doaj.org/article/166ef08bb7044db0858926d64cdcc259
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101116- (2022)
Summary: The functional and structural characterization of macromolecular complexes requires protocols for their native isolation. Here, we describe a protocol for this task based on the recombinant poxvirus Vaccinia expressing tagged proteins of int
Externí odkaz:
https://doaj.org/article/7ec03ed3153142edb635c25532d456ae