Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Uttapol Permpoon"'
Autor:
James Palacino, Pedro Lee, Hangyeol Jeong, Yeonjoon Kim, Yoojin Song, Uttapol Permpoon, Wesley Wong, Chen Bai, Nathan Fishkin, Khuloud Takouri, Eunjun Yu, Yong Yi, Anna Skaletskaya, Min-Soo Kim, Da-Yeong Kim, Dong-Ki Choi, Peter U. Park
Publikováno v:
Cancer Research. 83:2700-2700
Targeted protein degraders (TPDs) have expanded the breadth of therapeutic options through both their catalytic mechanism of action and ability to degrade previously “undruggable” target proteins. Prior reports of small-molecule GSPT1 degraders s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71b86ce68b21ee643f8dfae287c1ca67
https://doi.org/10.1158/1538-7445.am2023-2700
https://doi.org/10.1158/1538-7445.am2023-2700
Autor:
Joanne Lim, Anna Skaletskaya, Uttapol Permpoon, Yeonjoon Kim, Shikha Saini, Khuloud Takrouri, Zinaida Ribkovskaia, Palash Bhar, Nathan Fishkin, Dong-Ki Choi, Ji Hyun Park, James Palacino, Peter U. Park
Publikováno v:
Cancer Research. 83:4436-4436
It is well-established that T cells play a key role in the success of cancer immunotherapies. The goals of T cell-targeting therapies have been to restore the effector function of tumor-specific T cells that are either dysfunctional due to the immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ac3320da913310739ac2e45ee0f474
https://doi.org/10.1158/1538-7445.am2023-4436
https://doi.org/10.1158/1538-7445.am2023-4436
Autor:
James Palacino, Pedro Lee, Hangyeol Jeong, Yeonjoon Kim, Yoojin Song, Uttapol Permpoon, Wesley Wong, Chen Bai, Nathan Fishkin, Khuloud Takrouri, Eunjin Yu, Yong Yi, Anna Skaletskaya, Ki-Hwan Chang, Min-Soo Kim, Da-Yeong Kim, Dong-Ki Choi, Peter U Park
Publikováno v:
Blood. 140:3061-3062
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a269d96e6caa27fb8cac688926936eb0
https://doi.org/10.1182/blood-2022-168936
https://doi.org/10.1182/blood-2022-168936
Autor:
Peti Thuwajit, Gowri Rangaswamy Gunassekaran, Min-Jong Kim, Uttapol Permpoon, Fatima Khan, Smriti Gurung, Sang-Hyun Kim, Byung-Heon Lee, Sri Murugan Poonkavithai Vadevoo
Publikováno v:
Molecular Pharmaceutics. 17:4077-4088
Cholangiocarcinoma (CCA) has a poor prognosis and high chemoresistance. Interleukin-4 receptor (IL-4R) is overexpressed in several cancer cells and plays a crucial role in tumor progression and drug resistance. IL4RPep-1, an IL-4R-binding peptide, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90618633a666faf32133d3a41e821970
https://doi.org/10.1021/acs.molpharmaceut.0c00529
https://doi.org/10.1021/acs.molpharmaceut.0c00529
Autor:
Soyoun Kim, Gowri Rangaswamy Gunassekaran, Sri Murugan Poongkavithai Vadevoo, Enamul Haque, Smriti Gurung, Uttapol Permpoon, Soo-Woong Lee, Yun-Ki Lee, Fatima Khan, Lianhua Chi, Byung-Heon Lee
Publikováno v:
Theranostics
CD44v6, a splice variant of the cell surface glycoprotein CD44, acts as a co-receptor for c-Met and is upregulated in tumors with high metastatic potential. Methods: We screened a phage-displayed peptide library for peptides that selectively bind to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ea9f3ffb5d557ff91ac6615bafbd9c4
https://pubmed.ncbi.nlm.nih.gov/33391537
https://pubmed.ncbi.nlm.nih.gov/33391537
Autor:
Ji-Ho Park, Smriti Gurung, Gowri Rangaswamy Gunassekaran, Sang-Hyun Kim, Ha Jeong Kim, Soyoun Kim, Fatima Khan, Jae Do Yoo, In San Kim, Hyeonjeong Han, Sri Murugan Poongkavithai Vadevoo, Uttapol Permpoon, Byung-Heon Lee
Publikováno v:
Biomaterials. 247
Blockade of programmed cell death ligand-1 (PD-L1) restores T-cell activity and enhances anti-tumor immunity. Screening a phage-displayed peptide library for peptides that selectively bind to PD-L1-overexpressing cells identified two peptides, CLQKTP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2ad89437f6045425a657e4c204f762
https://pubmed.ncbi.nlm.nih.gov/32278214
https://pubmed.ncbi.nlm.nih.gov/32278214
Autor:
Md. Enamul Haque, Gowri Rangaswamy Gunassekaran, Byung-Heon Lee, Fatima Khan, Smriti Gurung, Lianhua Chi, Sri Murugan Poongkavithai Vadevoo, Uttapol Permpoon
Publikováno v:
Archives of pharmacal research. 42(2)
Peptides have advantages over antibodies in terms of deep tissue penetration, low immunogenicity, and cost-effective production, but they have short circulation time and poor stability in vivo. Peptides have been extensively used as targeting moietie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6cb3106601e6811bb1812e9144b71a5
https://pubmed.ncbi.nlm.nih.gov/30756310
https://pubmed.ncbi.nlm.nih.gov/30756310