Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Uttam R. Kalkote"'
Publikováno v:
Tetrahedron: Asymmetry. 26:281-287
The asymmetric synthesis of both the antipodes of α-lipoic acid is described. The total synthesis of racemic and asymmetric lipoic acid is achieved from propane 1,3-diol. This work reports the use of Mn (III)-salen-catalyzed oxidative kinetic resolu
Publikováno v:
Tetrahedron. 68:8509-8514
A highly diastereoselective synthesis of heritol and heritonin by intramolecular cyclization on a preformed sensitive butenolide functionality is described.
Publikováno v:
Synthetic Communications. 41:1938-1946
An efficient enantioselective synthesis of (S)-guaifenesin with >99% ee using L-proline-catalyzed α-aminoxylation of aldehyde as key step is described and explored for asymmetric syntheses of (S)-moprolol and (R)-methocarbamol.
Publikováno v:
Tetrahedron: Asymmetry. 22:587-590
A convenient synthesis of (2S,3S)-3-hydroxy pipecolic acid starting from inexpensive and easily available l -(+)-tartaric acid has been described.
Publikováno v:
Tetrahedron: Asymmetry. 20:1767-1770
An efficient enantioselective synthesis of β-adrenergic blockers (S)-propranolol and (S)-naftopidil with >98% ee using an l -proline-catalyzed α-aminoxylation of an aldehyde as a key step is described.
Publikováno v:
Synlett. 2008:2781-2784
An efficient synthesis of the DE ring of camptothecin, employing a Reformatsky and a tandem one-pot, three-step trans- formation involving aza-Michael reaction, condensation with ethyl malonyl chloride followed by intramolecular 'aldol' reaction to f
Publikováno v:
Synthesis. 2007:3827-3830
A one-pot cyclopentannulation approach as the key step for the total synthesis of (±)-α-cuparenone is described.
Publikováno v:
Synthetic Communications. 37:3901-3906
Publikováno v:
Synlett. 2007:2635-2638
The novel cascade intramolecular Pd-catalyzed cyclization followed by aromatization for the construction of D ring of (+)-camptothecin as a key step is demonstrated.
Autor:
Rajesh G. Gonnade, Uttam R. Kalkote, Harikisan R. Sonawane, Surendra G. Sudrik, Subhash P. Chavan, Mohan M. Bhadbhade, Sambhaji P. Chavan
Publikováno v:
European Journal of Organic Chemistry. 2007:3277-3280
A practical and convenient five-step protocol is described to access the ABC ring system of Taxol by utilizing the versatility of the sulfur atom in its various oxidation states viz., condensation/Pummerer cyclization/coupling/annulation/fragmentatio