Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Uttam K Rao"'
Autor:
Uttam K. Rao, Brian G. Engelhardt
Publikováno v:
Clinical Hematology International, Vol 2, Iss 3 (2020)
Patients undergoing allogeneic hematopoietic cell transplantation (HCT) are at risk for numerous acute and long-term complications from this procedure. Post-transplant diabetes mellitus (PTDM) is a common but under-recognized problem. Similar to graf
Externí odkaz:
https://doaj.org/article/c9bd8f039bfa41ad9def4f194a979726
Autor:
Marcel R.M. van den Brink, Derek Sant'Angelo, Martin G. Sauer, Michel Sadelain, Chen Liu, George F. Murphy, Cecilia Lezcano, Alan M. Hanash, Olaf Penack, Robert R. Jenq, Jennifer J. Tsai, Il-Kang Na, Hae Lee, Natalie V. Singer, Mallory L. West, Lauren F. Young, Uttam K. Rao, Nury L. Yim, Yildirim Dogan, Amanda M. Holland, Arnab Ghosh
Supplementary S1: PLZF expression affects CD4+ driven alloreactivity. Supplementary S2: PLZF-TG T cells undergo allo-activation that is similar to donor B6-WT T cells. Supplementary S3: Fewer deaths from GVHD are seen in BMT recipients of PLZF-TG T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810c8eb6280b2a8a46b785a10ae9e89f
https://doi.org/10.1158/0008-5472.22394780.v1
https://doi.org/10.1158/0008-5472.22394780.v1
Autor:
Sydney X Lu, Lucy W Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah, Amanda M Holland, Claire Turbide, Vanessa M Hubbard, Jimmy A Rotolo, Marsinay Smith, David Suh, Christopher King, Uttam K Rao, Nury Yim, Johanne L Bautista, Robert R Jenq, Olaf Penack, Il-Kang Na, Chen Liu, George Murphy, Onder Alpdogan, Richard S Blumberg, Fernando Macian, Kathryn V Holmes, Nicole Beauchemin, Marcel R M van den Brink
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21611 (2011)
Allogeneic bone marrow transplantation (allo-BMT) is a potentially curative therapy for a variety of hematologic diseases, but benefits, including graft-versus-tumor (GVT) activity are limited by graft-versus-host-disease (GVHD). Carcinoembryonic ant
Externí odkaz:
https://doaj.org/article/21a1cc5de81c4f2eb8783a27b6d7db01
Autor:
Salma Youssef, Chen Liu, Marcel R.M. van den Brink, Odette M. Smith, Amanda M. Holland, Alan M. Hanash, Yusuke Shono, Jarrod A Dudakov, Kimon V. Argyropoulos, Fabiana M Kreines, Sophie Lieberman, George F. Murphy, Cecilia Lezcano, Robert R. Jenq, Uttam K. Rao, Il-Kang Na, Jennifer Tsai, Nury L. Yim, Lauren F. Young, Enrico Velardi, Ya-Yuan Fu, Amina Lazrak
Nuclear factor erythroid-derived 2-like 2 (Nrf2) is a ubiquitously expressed transcription factor that is well known for its role in regulating the cellular redox pathway. Although there is mounting evidence suggesting a critical role for Nrf2 in hem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4c19adabc2348e72c4d8d66a65ac83
https://europepmc.org/articles/PMC6307985/
https://europepmc.org/articles/PMC6307985/
Autor:
George F. Murphy, Lauren F. Young, Michel Sadelain, Yildirim Dogan, Maxim A. Moroz, Enrico Velardi, Chen Liu, Nury L. Yim, Jennifer Tsai, Uttam K. Rao, Odette M. Smith, Robert R. Jenq, Daniel Tannenbaum, Alan M. Hanash, M. Lia Palomba, Vladimir Ponomarev, Cecilia Lezcano, Arnab Ghosh, Olaf Penack, Martin Sauer, Kelly Piersanti, Marcel R.M. van den Brink, Amanda M. Holland, Durva Masih
Publikováno v:
Journal of Clinical Investigation. 123:2654-2662
Current strategies to suppress graft-versus-host disease (GVHD) also compromise graft-versus-tumor (GVT) responses. Furthermore, most experimental strategies to separate GVHD and GVT responses merely spare GVT function without actually enhancing it.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bd5eeb15332349025aada322b0c29e8
https://doi.org/10.1172/jci66301
https://doi.org/10.1172/jci66301
Autor:
Marcel R.M. van den Brink, Arnab Ghosh, Jennifer Tsai, Ronald G. Blasberg, John C. Markley, Alexander D. Klose, Nury L. Yim, Bradley J. Beattie, Elmer Santos, Inna Serganova, Il-Kang Na, Renier J. Brentjens, Amanda M. Holland, Matthias Stephan, Uttam K. Rao, Michel Sadelain
Publikováno v:
Blood. 116:e18-e25
We have developed a dual bioluminescent reporter system allowing noninvasive, concomitant imaging of T-cell trafficking, expansion, and activation of nuclear factor of activated T cells (NFAT) in vivo. NFAT activation plays an important role in T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b12032ad31b768a3c541484d0b2866a
https://doi.org/10.1182/blood-2009-12-259432
https://doi.org/10.1182/blood-2009-12-259432
Autor:
Christine Volk, Christopher G. King, Onder Alpdogan, Gabrielle L. Goldberg, Odette M. Smith, Sydney X. Lu, Miguel-Angel Perales, Robert R. Jenq, Marcel R.M. van den Brink, Nury L. Yim, David Suh, Lucy W. Kappel, Amanda M. Holland, Uttam K. Rao, Adi Diab, Jedd D. Wolchok, Alan N. Houghton, Il-Kang Na, Olaf Penack, Johannes L. Zakrzewski
Publikováno v:
Blood. 113:1574-1580
Keratinocyte growth factor (KGF), which is given exogenously to allogeneic bone marrow transplantation (allo-BMT) recipients, supports thymic epithelial cells and increases thymic output of naive T cells. Here, we demonstrate that this improved T-cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d575bcf8ca3ea3ba1da0c1e7cf7b0dce
https://doi.org/10.1182/blood-2008-05-155697
https://doi.org/10.1182/blood-2008-05-155697
Publikováno v:
Academic Medicine. 81:164-170
PurposeTo assess the attitudes of medical students in India about participating in graduate medical education in the United States and other countries and in subsequent clinical practice in those countries.MethodA total of 240 students who were atten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::830086da2400509a0a813a90318f396c
https://doi.org/10.1097/00001888-200602000-00015
https://doi.org/10.1097/00001888-200602000-00015
Publikováno v:
Academic Medicine. 81:185-188
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d435456b622a5483615cc38f20571fa
https://doi.org/10.1097/00001888-200602000-00020
https://doi.org/10.1097/00001888-200602000-00020
Autor:
Jennifer Tsai, Michel Sadelain, Marcel R.M. van den Brink, Hae Lee, Amanda M. Holland, Nury L. Yim, George F. Murphy, Chen Liu, Derek B. Sant'Angelo, Cecilia Lezcano, Alan M. Hanash, Uttam K. Rao, Il-Kang Na, Martin Sauer, Lauren F. Young, Mallory L. West, Natalie V. Singer, Robert R. Jenq, Arnab Ghosh, Olaf Penack, Yildirim Dogan
Publikováno v:
Cancer research. 73(15)
Efforts to limit GVHD mediated by alloreactive donor T cells after allogeneic bone marrow transplantation are limited by a concomitant decrease in graft-versus-tumor (GVT) activity and increased possibilities of tumor relapse. Using a novel approach,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4a2b5467c18a8fd9491457e48a9d01
https://pubmed.ncbi.nlm.nih.gov/23733752
https://pubmed.ncbi.nlm.nih.gov/23733752