Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin

Autor: Ji-Hak, Jeong, Uttam, Ojha, Hyeonha, Jang, Soohyun, Kang, Sunhee, Lee, You Mie, Lee

Publikováno v: Cellular Oncology. 46:117-132

Tumor microenvironment consists of various kind of cells, forming complex interactions and signal transductions for tumor growth. Due to this complexity, targeting multiple kinases could yield improved clinical outcomes. In this study, we aimed to in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8e6e914d6de5e7e356e9de04bd0eeb
https://doi.org/10.1007/s13402-022-00737-x

Contributors

Autor: Mahendra Adhikari, Achyut Adhikari, Yagya P. Adhikari, Dhaka M. Adhikari, Anjana Adhikari-Devkota, Vasudha Agnihotri, Pramod Aryal, Muhammad Ashraf, Dharam C. Attri, Muhammad Ayaz, Amit Bahukhandi, Tonking Bastola, Tarun Belwal, Ravin Bhandari, Prabin Bhandari, Indra D. Bhatt, Nilesh Bhowmick, Anil Kumar Bisht, Arti Bisht, Monika Bisht, Devanjal Bora, Harsh Kumar Chauhan, Sumit Bahadur Baruwal Chhetri, null Jamyang Choden, Manisha Choudhury, Jeevani Maheshika Dahanayake, Munmee Das, Agnidipta Das, Niranjan Das, Khashti Dasila, Himadri Shekhar Datta, Fatma Tugce Guragac Dereli, Hari Prasad Devkota, Bhawana Dhakal, Amina Ibrahim Dirar, Sumit Durgapal, Medha Durgapal, Bindu Gurung, null Choki Gyeltshen, Md. Mahadi Hassan, Asha Humbal, Ashmita Jaishi, Arvind Jantwal, Vinod Chandra Joshi, Pushpa Kewlani, Deepa Khatri, Sunil Kumar, Ripu M. Kunwar, Gopal Lamichhane, Santosh Lamichhane, Rajan Logesh, Sudip Kumar Mandal, Baiakmenlang Manners, Tanuja Mehra, Abhay Prakash Mishra, Sunayana Nath, Asif Nawaz, Vikram S. Negi, Manoranjan Neog, Manisha Nigam, Uttam Ojha, Sheetal Oli, Jitendra Pandey, Prakash Raj Pandeya, Vartika Pant, Pravin Parajuli, Polu Parameshwar, Ravi Pathak, Hem Raj Paudel, Mukti Ram Paudel, Pathirage Kamal Perera, Tamlal Pokhrel, Amrit Poudel, Prakash Poudel, Muna Poudel, Mukti Ram Poudeyal, Manashi Das Purkayastha, Mahendra Rana, Ranbeer S. Rawal, Sandeep Rawat, Abdul Sadiq, Kusum Sai, Biswash Sapkota, Bishnu Prasad Sarma, Saravanan Vivek Sathasivampillai, Clara E. Sawian, Jasmine T. Sawian, Jyoti Saxena, Kapil Mohan Sharma, Grinsun Sharma, Pramila Sharma, Dheeraj Shootha, Ritis Kumar Shyanti, Dolly Singh, Bikarma Singh, Mithilesh Singh, Sushil Kumar Singh, Basant Singh, Laxman Singh, Bishnu Bahadur Sinjali, Aldonna M. Susngi, Rashmi Thapa, Deepak Timalsina, Amrendra Kumar Tiwari, Deep C. Tiwari, Deepti Tiwari, null Tshering Dorji, Farhat Ullah, Jyoti Upadhyay, Zhanibek Yessimbekov, Erkan Yilmaz

Publikováno v: Himalayan Fruits and Berries ISBN: 9780323855914

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ddf78425c3d22f8f563694e9de250693
https://doi.org/10.1016/b978-0-323-85591-4.00080-5

Intermittent fasting protects the nigral dopaminergic neurons from MPTP-mediated dopaminergic neuronal injury in mice

Autor: Uttam Ojha, Shristi Khanal, Pil-Hoon Park, Jin Tae Hong, Dong-Young Choi

Publikováno v: The Journal of Nutritional Biochemistry. 112:109212

Dietary restriction through low-calorie intake or intermittent fasting benefits many organs, including the brain. This study investigated the neuroprotective effects of fasting in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742d0c0cfefabb7e07cdbd583cc5ee03
https://doi.org/10.1016/j.jnutbio.2022.109212

Enhanced dopaminergic neurotoxicity mediated by MPTP in IL-32β transgenic mice

Autor: Dong-Young Choi, Uttam Ojha, Sina Shadfar, Jin Tae Hong, Sunil Bhurtel, Do Young Yoon, Sunil Srivastav, Pil-Hoon Park, Yu Yeon Jung, Nikita Katila, Dong Ju Son, Sabita Neupane

Publikováno v: Neurochemistry International. 102:79-88

Parkinson's disease (PD) is a neurodegenerative disorder characterized by prominent loss of the nigral dopaminergic neurons and motor symptoms, such as resting tremor and bradykinesia. Evidence suggests that neuroinflammation may play a critical role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abe36623580767e3ba1e5352e9cc8fa
https://doi.org/10.1016/j.neuint.2016.12.002

Correction for Kang et al., Increased intracellular Ca 2+ concentrations prevent membrane localization of PH domains through the formation of Ca 2+ -phosphoinositides

Autor: Uttam Ojha

Publikováno v: Proceedings of the National Academy of Sciences. 114

Insulin resistance, a key etiological factor in metabolic syndrome, is closely linked to ectopic lipid accumulation and increased intracellular Ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29402d4192b3f77e03bd32987e2f83
https://doi.org/10.1073/pnas.1719887115