Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Uttam, Khamrai"'
Autor:
Mark Merris, William G. Wadsworth, Uttam Khamrai, Robert Bittman, David J. Chitwood, John Lenard
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 172-181 (2003)
Caenorhabditis elegans requires sterol, usually supplied as cholesterol, but this is enzymatically modified, and different sterols can substitute. Sterol deprivation decreased brood size and adult growth in the first generation, and completely, rever
Externí odkaz:
https://doaj.org/article/f5324d9702cb4710ae139a7449b7728e
Autor:
Tanmay K, Pati, Sk, Ajarul, Mrinalkanti, Kundu, Deepak, Tayde, Uttam, Khamrai, Dilip K, Maiti
Publikováno v:
The Journal of organic chemistry. 85(13)
We have identified different N-substituted 2-pyridones as inbuilt directing groups for selective C-H-activated functionalization instead of deprotecting and/or throwing away the directing groups. A robust general method for external ligand-free Pd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dff2904ce6d98f8a7c37bb5ab4bca8b
https://pubmed.ncbi.nlm.nih.gov/32574496
https://pubmed.ncbi.nlm.nih.gov/32574496
Publikováno v:
Organic Letters. 20:4062-4066
A new bidentate directing group, 3-amino-1-methyl-1H-pyridin-2-one, is introduced to achieve a powerful PdII metallacycle for selective γ-C(sp3)–H activation and arylation of aromatic and aliphatic carboxylic acid derivatives. The versatility of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::470685508e659a32e579be4fe9377ceb
https://doi.org/10.1021/acs.orglett.8b01618
https://doi.org/10.1021/acs.orglett.8b01618
Autor:
Uttam Khamrai, Jumpei Aida, Mrinalkanti Kundu, Tsuneo Yasuma, Mikio Shirasaki, Shoki Okuda, Shizuo Kasai, Syunsuke Yamamoto, Asato Kina, Masashi Takahashi, Toshihiro Noguchi, Yasutaka Nagisa, Yayoi Kawata, Hideyuki Igawa, Minoru Ikoma, Yasushi Fujioka, Keiko Kakegawa, Tsuyoshi Maekawa, Masaharu Nakayama
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:2486-2503
Melanin-concentrating hormone (MCH) is an attractive target for antiobesity agents, and numerous drug discovery programs are dedicated to finding small-molecule MCH receptor 1 (MCHR1) antagonists. We recently reported novel pyridine-2(1 H )-ones as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbada861a07cfc93c3c995d6e8118a2e
https://doi.org/10.1016/j.bmc.2016.04.011
https://doi.org/10.1016/j.bmc.2016.04.011
Publikováno v:
Organic letters. 20(13)
A new bidentate directing group, 3-amino-1-methyl-1 H-pyridin-2-one, is introduced to achieve a powerful Pd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6c01e8dbbc1a406f23a5c80331432ed3
https://pubmed.ncbi.nlm.nih.gov/29894193
https://pubmed.ncbi.nlm.nih.gov/29894193
Autor:
Uttam Khamrai, Shizuo Kasai, Minoru Ikoma, Asato Kina, Masaharu Nakayama, Jumpei Aida, Keiko Kakegawa, Yasutaka Nagisa, Masashi Takahashi, Syunsuke Yamamoto, Hideki Hirabayashi, Tsuneo Yasuma, Hideyuki Igawa, Mrinalkanti Kundu, Yayoi Kawata, Tsuyoshi Maekawa, Shuntaro Ashina
Publikováno v:
Journal of medicinal chemistry. 59(3)
Aiming to discover melanin-concentrating hormone receptor 1 (MCHR1) antagonists with improved safety profiles, we hypothesized that the aliphatic amine employed in most antagonists reported to date could be removed if the bicyclic motif of the compou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1b24ef32e31082e678f0e27b3a6ab4
https://pubmed.ncbi.nlm.nih.gov/27045534
https://pubmed.ncbi.nlm.nih.gov/27045534
Autor:
John Lenard, William G. Wadsworth, Mark Merris, Uttam Khamrai, David J. Chitwood, Robert Bittman
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 1, Pp 172-181 (2003)
Caenorhabditis elegans requires sterol, usually supplied as cholesterol, but this is enzymatically modified, and different sterols can substitute. Sterol deprivation decreased brood size and adult growth in the first generation, and completely, rever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ce239b2baeeb0a3e08095bc4abb350
https://doi.org/10.1194/jlr.m200323-jlr200
https://doi.org/10.1194/jlr.m200323-jlr200
Autor:
Hideyuki Igawa, Masashi Takahashi, Keiko Kakegawa, Asato Kina, Minoru Ikoma, Jumpei Aida, Tsuneo Yasuma, Yayoi Kawata, Shuntaro Ashina, Syunsuke Yamamoto, Mrinalkanti Kundu, Uttam Khamrai, Hideki Hirabayashi, Masaharu Nakayama, Yasutaka Nagisa, Shizuo Kasai, Tsuyoshi Maekawa
Publikováno v:
Journal of Medicinal Chemistry. 59:3577-3577
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8436c88594ce554dabe1eb107285fb7f
https://doi.org/10.1021/acs.jmedchem.6b00433
https://doi.org/10.1021/acs.jmedchem.6b00433