Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Utsa Bhaduri"'
Autor:
Fabio Coppedè, Utsa Bhaduri, Andrea Stoccoro, Vanessa Nicolì, Eleonora Di Venere, Giuseppe Merla
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11715 (2023)
The central objective of the metamorphosis of discovery science into biomedical applications is to serve the purpose of patients and curtail the global disease burden. The journey from the discovery of DNA methylation (DNAm) as a biological process t
Externí odkaz:
https://doaj.org/article/c97af1cd6275441eb94206f58e478b14
Autor:
Vasantha Shalini, Utsa Bhaduri, Anjhana C. Ravikkumar, Anusha Rengarajan, Rao M. R. Satyanarayana
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-25 (2021)
Abstract Background H1T2/H1FNT is a germ cell-specific linker histone variant expressed during spermiogenesis specifically in round and elongating spermatids. Infertile phenotype of homozygous H1T2 mutant male mice revealed the essential function of
Externí odkaz:
https://doaj.org/article/266cc04628e448febf4ae034bda6fa07
Autor:
Utsa Bhaduri, Giuseppe Merla
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 434-444 (2020)
The human tripartite motif containing protein 8 (TRIM8), a member of TRIM family proteins, is known to play a dual role as both tumor suppressor and oncogene, and to function at the crosstalk of cancer and innate immunity. In this review, in addition
Externí odkaz:
https://doaj.org/article/6aef7a0d8f8a4e039fa70786ebe379d2
Publikováno v:
Non-coding RNA Research, Vol 4, Iss 3, Pp 96-108 (2019)
Noncoding RNAs are increasingly being accredited with key roles in gene regulation during development and disease. Here we report the discovery and characterization of a novel long noncoding RNA, Hmrhl, which shares synteny and partial sequence simil
Externí odkaz:
https://doaj.org/article/22bb779dabb64386ab04bd27857b3856
Autor:
Iyer Aditya Mahadevan, Satyakrishna Pentakota, Raktim Roy, Utsa Bhaduri, Manchanahalli R. Satyanarayana Rao
Publikováno v:
Epigenetics & Chromatin, Vol 12, Iss 1, Pp 1-23 (2019)
Abstract Background TH2B is a major histone variant that replaces about 80–85% of somatic H2B in mammalian spermatocytes and spermatids. The post-translational modifications (PTMs) on TH2B have been well characterised in spermatocytes and spermatid
Externí odkaz:
https://doaj.org/article/0d88d5d3cacc465eb06dd01575ca849e
Autor:
Debosree Pal, C.V. Neha, Utsa Bhaduri, Zenia Zenia, Sangeeta Dutta, Subbulakshmi Chidambaram, M.R.S. Rao
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102250- (2021)
Long non-coding RNAs (lncRNAs) have been well-established to act as regulators and mediators of development and cell fate specification programs. LncRNA Mrhl (meiotic recombination hotspot locus) has been shown to act in a negative feedback loop with
Externí odkaz:
https://doaj.org/article/343950f6146843b2b1964f871f7bda2a
Autor:
Laxmi Narayan Mishra, Vasantha Shalini, Nikhil Gupta, Krittika Ghosh, Neeraj Suthar, Utsa Bhaduri, M. R. Satyanarayana Rao
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-21 (2018)
Abstract Background Linker histones establish and maintain higher-order chromatin structure. Eleven linker histone subtypes have been reported in mammals. HILS1 is a spermatid-specific linker histone, and its expression overlaps with the histone–pr
Externí odkaz:
https://doaj.org/article/81f7e4ec007446529d2bb2da382207a5
Autor:
Utsa Bhaduri, Giuseppe Merla
Publikováno v:
Cells, Vol 10, Iss 5, p 1015 (2021)
Ubiquitination is a post-translational modification that has pivotal roles in protein degradation and diversified cellular processes, and for more than two decades it has been a subject of interest in the biotech or biopharmaceutical industry. Tripar
Externí odkaz:
https://doaj.org/article/74a600fc1426406a8ddbf4dc9b1057f2
Publikováno v:
Mol Cell Biol
The long noncoding RNA (lncRNA) Mrhl has been shown to be involved in coordinating meiotic commitment of mouse spermatogonial progenitors and differentiation events in mouse embryonic stem cells. Here, we characterized the interplay of Mrhl with line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c1da23e9796ba182c50c515328b40c
https://europepmc.org/articles/PMC9670966/
https://europepmc.org/articles/PMC9670966/
Autor:
Aditya Bhattacharya, Sourav Chatterjee, Utsa Bhaduri, Akash Kumar Singh, Madavan Vasudevan, Koneni V. Sashidhara, Rajdeep Guha, Aamir Nazir, Srikanta Kumar Rath, Nagashayana Natesh, Tapas K. Kundu
Publikováno v:
Journal of medicinal chemistry. 65(18)
The enzyme p300, besides having acetyltransferase activity, can also catalyze other acylation modifications, whose physiological implications are still being investigated. Here, we report that the level of histone butyrylation increases globally as w