Výsledky vyhledávání - "Utpal, Nandi"

Akademický článek

Gentiacaulein inhibits glucose transport to induce PRKAA1-mediated autophagy to clear amyloid beta and associated inflammation in primary astrocytes

Autor: Ankita Sharma, Sukhleen Kaur, Abubakar Wani, Dilpreet Kour, Mehboob Ali, Syed Mudassir Ali, Lakhvinder Singh, Abhishek Gour, Utpal Nandi, Manish Datt, Parduman Raj Sharma, Conrad C Weihl, Gurdarshan Singh, Ajay Kumar

Publikováno v: Autophagy Reports, Vol 3, Iss 1 (2024)

ABSTRACTBeing present in substantial numbers, astrocytes play an indispensable role in maintaining homeostasis in the brain. However, their positive or negative involvement in pathological conditions in the brain has not been explored much. In recent

Externí odkaz: https://doaj.org/article/25c78f4100fa46be8e209b6d79865ea0

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Akademický článek

Discovery of a novel and highly selective JAK3 inhibitor as a potent hair growth promoter

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)

Abstract JAK-STAT signalling pathway inhibitors have emerged as promising therapeutic agents for the treatment of hair loss. Among different JAK isoforms, JAK3 has become an ideal target for drug discovery because it only regulates a narrow spectrum

Externí odkaz: https://doaj.org/article/64faa3ccd8d24a228b59d9fca5872f55

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Akademický článek

SWOSBC: A Novel Optimizer for Learning Convolutional Neural Network

Autor: Shubhankar Bhakta, Utpal Nandi, Kuheli Ray Mahapatra, Moirangthem Marjit Singh, Abdulfattah Noorwali

Publikováno v: IEEE Access, Vol 12, Pp 156458-156470 (2024)

Deep Neural Networks (DNNs) that aim to maximize accuracy and decrease loss can be trained using optimization algorithms. One of the most significant fields of research is the creation of an efficient optimization technique. Most adaptive optimizers,

Externí odkaz: https://doaj.org/article/0bff71c37b474f5a8fef058b132663f0

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Akademický článek

Opposition-Based Chaotic Tunicate Swarm Algorithms for Global Optimization

Autor: Tapas Si, Pericles B. C. Miranda, Utpal Nandi, Nanda Dulal Jana, Saurav Mallik, Ujjwal Maulik, Hong Qin

Publikováno v: IEEE Access, Vol 12, Pp 18168-18188 (2024)

Tunicate Swarm Algorithm (TSA) is a novel swarm intelligence algorithm developed in 2020. Though it has shown superior performance in numerical benchmark function optimization and six engineering design problems over its competitive algorithms, it st

Externí odkaz: https://doaj.org/article/c7186754937342d4930e2bde69e90e21

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Akademický článek

A novel ensemble learning-based model for network intrusion detection

Autor: Ngamba Thockchom, Moirangthem Marjit Singh, Utpal Nandi

Publikováno v: Complex & Intelligent Systems, Vol 9, Iss 5, Pp 5693-5714 (2023)

Abstract The growth of Internet and the services provided by it has been growing exponentially in the past few decades. With such growth, there is also an ever-increasing threat to the security of networks. Several efficient countermeasures have been

Externí odkaz: https://doaj.org/article/aa18b0d92dab49c3bba54efc1625e45f

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Akademický článek

PCOBL: A Novel Opposition-Based Learning Strategy to Improve Metaheuristics Exploration and Exploitation for Solving Global Optimization Problems

Autor: Tapas Si, Debolina Bhattacharya, Somen Nayak, Pericles B. C. Miranda, Utpal Nandi, Saurav Mallik, Ujjwal Maulik, Hong Qin

Publikováno v: IEEE Access, Vol 11, Pp 46413-46440 (2023)

Meta-heuristics are commonly applied to solve various global optimization problems. In order to make the meta-heuristics performing a global search, balancing their exploration and exploration ability is still an open avenue. This manuscript proposes

Externí odkaz: https://doaj.org/article/0e1019ef4a034b2b97ffec4b90405a85

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