Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Autor: Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee

Publikováno v: eLife, Vol 10 (2021)

Mechanistic studies of Drosophila lymph gland hematopoiesis are limited by the availability of cell-type-specific markers. Using a combination of bulk RNA-Seq of FACS-sorted cells, single-cell RNA-Seq, and genetic dissection, we identify new blood ce

Externí odkaz: https://doaj.org/article/b5c668a8e4d744bdbdb753ddb87caae0

Expression-Based Cell Lineage Analysis in Drosophila Through a Course-Based Research Experience for Early Undergraduates

Autor: John M. Olson, Cory J. Evans, Kathy T. Ngo, Hee Jong Kim, Joseph Duy Nguyen, Kayla G. H. Gurley, Truc Ta, Vijay Patel, Lisa Han, Khoa T. Truong-N, Letty Liang, Maggie K. Chu, Hiu Lam, Hannah G. Ahn, Abhik Kumar Banerjee, In Young Choi, Ross G. Kelley, Naseem Moridzadeh, Awais M. Khan, Omair Khan, Szuyao Lee, Elizabeth B. Johnson, Annie Tigranyan, Jay Wang, Anand D. Gandhi, Manish M. Padhiar, Joseph Hargan Calvopina, Kirandeep Sumra, Kristy Ou, Jessie C. Wu, Joseph N. Dickan, Sabrena M. Ahmadi, Donald N. Allen, Van Thanh Mai, Saif Ansari, George Yeh, Earl Yoon, Kimberly Gon, John Y. Yu, Johnny He, Jesse M. Zaretsky, Noemi E. Lee, Edward Kuoy, Alexander N. Patananan, Daniel Sitz, PhuongThao Tran, Minh-Tu Do, Samira J. Akhave, Silverio D. Alvarez, Bobby Asem, Neda Asem, Nicole A. Azarian, Arezou Babaesfahani, Ahmad Bahrami, Manjeet Bhamra, Ragini Bhargava, Rakesh Bhatia, Subir Bhatia, Nicholas Bumacod, Jonathan J. Caine, Thomas A. Caldwell, Nicole A. Calica, Elise M. Calonico, Carman Chan, Helen H.-L. Chan, Albert Chang, Chiaen Chang, Daniel Chang, Jennifer S. Chang, Nauman Charania, Jasmine Y. Chen, Kevin Chen, Lu Chen, Yuyu Chen, Derek J. Cheung, Jesse J. Cheung, Jessica J. Chew, Nicole B. Chew, Cheng-An Tony Chien, Alana M. Chin, Chee Jia Chin, Youngho Cho, Man Ting Chou, Ke-Huan K. Chow, Carolyn Chu, Derrick M. Chu, Virginia Chu, Katherine Chuang, Arunit Singh Chugh, Mark R. Cubberly, Michael Guillermo Daniel, Sangita Datta, Raj Dhaliwal, Jenny Dinh, Dhaval Dixit, Emmylou Dowling, Melinda Feng, Christopher M. From, Daisuke Furukawa, Himaja Gaddipati, Lilit Gevorgyan, Zunera Ghaznavi, Tulika Ghosh, Jaskaran Gill, David J. Groves, Kalkidan K. Gurara, Ali R. Haghighi, Alexandra L. Havard, Nasser Heyrani, Tanya Hioe, Kirim Hong, Justin J. Houman, Molly Howland, Elaine L. Hsia, Justin Hsueh, Stacy Hu, Andrew J. Huang, Jasmine C. Huynh, Jenny Huynh, Chris Iwuchukwu, Michael J. Jang, An An Jiang, Simran Kahlon, Pei-Yun Kao, Manpreet Kaur, Matthew G. Keehn, Elizabeth J. Kim, Hannah Kim, Michelle J. Kim, Shawn J. Kim, Aleksandar Kitich, Ross A. Kornberg, Nicholas G. Kouzelos, Jane Kuon, Bryan Lau, Roger K. Lau, Rona Law, Huy D. Le, Rachael Le, Carrou Lee, Christina Lee, Grace E. Lee, Kenny Lee, Michelle J. Lee, Regina V. Lee, Sean H. K. Lee, Sung Kyu Lee, Sung-Ling D. Lee, Yong Jun Lee, Megan J. Leong, David M. Li, Hao Li, Xingfu Liang, Eric Lin, Michelle M. Lin, Peter Lin, Tiffany Lin, Stacey Lu, Serena S. Luong, Jessica S. Ma, Li Ma, Justin N. Maghen, Sravya Mallam, Shivtaj Mann, Jason H. Melehani, Ryan C. Miller, Nitish Mittal, Carmel M. Moazez, Susie Moon, Rameen Moridzadeh, Kaley Ngo, Hanh H. Nguyen, Kambria Nguyen, Thien H. Nguyen, Angela W. Nieh, Isabella Niu, Seo-Kyung Oh, Jessica R. Ong, Randi K. Oyama, Joseph Park, Yaelim A. Park, Kimberly A. Passmore, Ami Patel, Amy A. Patel, Dhruv Patel, Tirth Patel, Katherine E. Peterson, An Huynh Pham, Steven V. Pham, Melissa E. Phuphanich, Neil D. Poria, Alexandra Pourzia, Victoria Ragland, Riki D. Ranat, Cameron M. Rice, David Roh, Solomon Rojhani, Lili Sadri, Agafe Saguros, Zainab Saifee, Manjot Sandhu, Brooke Scruggs, Lisa M. Scully, Vanessa Shih, Brian A. Shin, Tamir Sholklapper, Harnek Singh, Sumedha Singh, Sondra L. Snyder, Katelyn F. Sobotka, Sae Ho Song, Siddharth Sukumar, Halley C. Sullivan, Mark Sy, Hande Tan, Sara K. Taylor, Shivani K. Thaker, Tulsi Thakore, Gregory E. Tong, Jacinda N. Tran, Jonathan Tran, Tuan D. Tran, Vivi Tran, Cindy L. Trang, Hung G. Trinh, Peter Trinh, Han-Ching H. Tseng, Ted T. Uotani, Akram V. Uraizee, Kent K. T. Vu, Kevin K. T. Vu, Komal Wadhwani, Paluk K. Walia, Rebecca S. Wang, Shuo Wang, Stephanie J. Wang, Danica D. Wiredja, Andrew L. Wong, Daniel Wu, Xi Xue, Griselda Yanez, Yung-Hsuan Yang, Zhong Ye, Victor W. Yee, Cynthia Yeh, Yue Zhao, Xin Zheng, Anke Ziegenbalg, Jon Alkali, Ida Azizkhanian, Akash Bhakta, Luke Berry, Ryen Castillo, Sonja Darwish, Holly Dickinson, Ritika Dutta, Rahul Kumar Ghosh, Riley Guerin, Jonathan Hofman, Garrick Iwamoto, Sarah Kang, Andrew Kim, Brian Kim, Hanwool Kim, Kristine Kim, Suji Kim, Julie Ko, Michael Koenig, Alejandro LaRiviere, Clifton Lee, Jiwon Lee, Brandon Lung, Max Mittelman, Mark Murata, Yujin Park, Daniel Rothberg, Ben Sprung-Keyser, Kunal Thaker, Vivian Yip, Paul Picard, Francie Diep, Nikki Villarasa, Volker Hartenstein, Casey Shapiro, Marc Levis-Fitzgerald, Leslie Jaworski, David Loppato, Ira E. Clark, Utpal Banerjee

Publikováno v: G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3791-3800 (2019)

A variety of genetic techniques have been devised to determine cell lineage relationships during tissue development. Some of these systems monitor cell lineages spatially and/or temporally without regard to gene expression by the cells, whereas other

Externí odkaz: https://doaj.org/article/873517b69ed547f291031d338d321d26

A functional genomics screen identifying blood cell development genes in Drosophila by undergraduates participating in a course-based research experience

Autor: Ryan Chan, Joshua P Hedtke, Michael T Chang, Kristen M Omi, Namrata Kakade, William Y. Luo, Yurianna Hou, Gloria Chin Young, Sunjong Ji, Mai Abdusamad, Amy Ngo, Maggie M Yung, Carissa Chan, Sharon Lee, Mark R Murata, Ashwin Shinde, Jason P Xu, Angelica C Ayala, Emily Jin Kyung Kim, Elitzander Alegria‐Leal, Phuong Vo, Yuan Wan, Vivian K Chen, Raghav Goyal, Anabel Resendiz, Harin B Parikh, Jaime S Tan, Leah C Dorman, Annisa N Soeboer, Seethim Naicker, Pratyush Kandimalla, Petros S Dertsakyan, Faith A Hobby, Beatrice J Sun, Karen Hoi, Megha Pokhriyal, C Kimberly Tsui, Nguyen Khoi Le, Umar Chaudhary, Patrick Chin, Woo Kyeom Kim, Mengshi He, David A Sanville, Utpal Banerjee, Christine Sutanto, Tiffany Luu, Joshua Lin, Tony Yao, Josephine Liu, Janani Muthaiya, Ravinder Kaur, Steven V. Pham, Andrea Vega-Loza, Mia Lim, Nataliya S Balashova, Adam T Quaal, Hnin Hlaing, Patrick A. Truong, Bryan Stender, Harmanjit Bassi, Erwin Feng, Yuxuan Wang, Sarah Salarkia, Rina H Nguyen, Gloria Lam, Garuem Sin, Seong Ah Kim, Sindhuja Godavarthi, Jialing Li, Eileen Hu, Cindy La, Elaine Sang, Jun Ho Chung, Jinhua Shen, Celesti Hao, Josh Mytych, Elliott Wu, Jin Hee Kim, Duy Tran, Neel Chari, Andie O'Laughlin, Christopher J Smith, Mona Abutouk, Chak Lon Kuang, Pei-Hua Tsai, Alisa Sukhina, Li Li, Chongbin He, Daniel Wong, Jahzeel Paguntalan, Emily R Schoen, Edgar Corona, Vivian Yip, Trisha H Patel, Emily Kim, Ira E. Clark, Andrew Char, Guadalupe Ortega Almazan, Asmar Abdul Ghani, Nadiyah Priasti, Duy Q Ngo, Gabrielle Sibal, Sean P Bennion, Stephanie Pang, Vivien W. Ho, Rachel S Distler, Nateli Sama, Josef Madrigal, Maharshi Panchal, Zijie Cai, Ashley C. Hope, Miriam Beyder, Daphne Jin, Steven C Liu, John M. Olson, Janice Ly, Eric Wang, Irene Louie, Wilson Huang, Justin Rafael de la Fuente, Nathan Stutzman, Bilguudei Naranbaatar, Rose Graf, Jonelle Mungcal, Jason Capili, Ziqi Zhou, Kelly M Gu, Julie Ko, Jeffrey A Kho, Amber J Li, Daniel Tran, Cory J. Evans, Jocelyn Woo, Kristen Schnell, Praptee Chowdhury, Chi Ju Lee, Grace J. Lee, Tracy L. Johnson, Nadezhda Riabkova, David Lopatto, Amanda Phan, Mary C Onglatco, Stephanie Huang, Zhiqiao Dong, Sat Kartar Khalsa, Saurin Kadakia, Maique Vo, Jessica Ye, Eric Lin, Darron Miya, Julia A. Ainsworth, Nicholas James, Jonathan Chang, Chloe C Su, Jeffrey Lin, Leslie Jaworski, Jenna Kovsky, Alice Hsu, Michel Chen, Allysen B Ehresman, Ju-Yeon Lee, Talin Golnazarian, Dana Lee, Kai Y Alexander, Jill Zimmerman, Lauren Johnson, Bosco Q Giap, Jamlah Dalie, Jackson K Uriu, Amala John, Osvaldo Acosta, Tebogo Mokwena, Sanan Venkatesh, Brandon L. Tsai, Haris M Akram, Seo-Kyung Oh, Andrea T Fua, Mark A Douglass, Rebecca Yang, Jessica M. Lee, Derek Spitters, Carmen Javier, Alex W Chan, Richard Wong, Ivy H Fu, Connie Y Liu, Parich Tangmatitam, Sena Ji, Claire Park, Arash Ghaffari-Rafi, Vincent T Nguyen, Dorothy Yim, Kush V. Bhatt, Tonatiuh Montoya, Rayna Tian, Vivian Chiu, Malcolm Phung, Victoria Lee, Chinmay Bhoot, Purvi D Patel, Jensen Pak, Puja Yogi, Zhouyang Shen, Nhat-Thi Vo, Bama Charan Mondal, Davis W Popovich, Mane Williams, Oscar M A Del Rio, Alexander J Chassiakos, Ruth Ryu, Zijun Zhao, Renae L Cruz, Yishan Mai, Michael K Wang, Kenneth Chang Chien, Kayla Patel, Jun Wang, Courtney J Cruz, Nicholas J Gills, Alexis Baranoff, Dinali Wijiewarnasurya, Yancey Y Cashell, Iman Hamid, Ashley Hanson, Olivia L Lee, Jasmine Sjarif, Patrick W Chang, Jasmin Johal, Monica Ghaly, Momoko Ishii, Alexandra M Libro, Boyu Cao, Paras Shah, Jennifer Hsueh, Aaron W Bradshaw, Jagteshwar Singh Khatra, Tien M Phan-Everson, Jonathan Lai, David J. Lim, Na Eun Jeon, Caleb Kim, Hyun Wook Kim, Hannah Kim, Sean Full, Tierney G Brannigan, Inho Chang, Suhas P Dasari, Emily R Dennis, Ceejay Lee, Alexander Zai, Christine Zhang, Ayse Elif Kesaf, Ralph Albert, Rebecca M Barber, Shijia W Lu, Austin Ma, Spencer S Hu, Ipsita Dey, Hee Jong Kim, Nancy Ruano, Timothy C Voros, Sarah M. Kamel, Kimberly L Yan, Gah-Eun Jang, Dallas L Mould, Eduardo Hernandez, Sahra M Hosseinian, Iris Chen, Chon Ao, Cindy K Trac, Eric Y Du, Sam Law, Ysrael K Hernandez, Jeffrey S. Zhao, Angad Beniwal, Patricia Yeo, Vina Tran, James R. Lee, Manny Sosa, Zheying Chen, Alec Estrada, Cristian Sosa, Kevin Herrera, Mina Mohammadi, Rina Watanabe, Timothy Chai, Huy Nguyen, Dong Yeon Lee, Vishaal Yepuri, Melanie Huynh, Kyle Marik, Thao T T Nguyen, Xiao X Zhang, Jamie A Ngo, Anh Nguyen, Colton Bracken, Brandon Wei, Brian Aguirre, Sayonika Mohanta, Jeffrey C. Wang, Casey Shapiro, Sonia Gill, Fred Rong, Lauren Petersen, Pingdi Huang, Alexander Grunfeld, Sang Kuk Lee, An N Ha, Kevin Nishida, Shraddha Kumar, Terrence C Lee, Ariano Abbasi, Jenny Summapund, Karl Querubin, Siman Wei, Hanning Xing, Evan Yang, Liset Contreras, Sahar Yaftaly, Matthew Wilson, Ken Siangchin, Brian Kit, Mallory R Neebe, Irvin C Lien, Julia E Petersen, Jonathan Woo, Kaitlyn Honeychurch, Jesse Juarez, Stephen Chang, Raymond Zhou, Cristian Medina, Sean Louise G Laput, Jason T. Lee, Nguon L Tan, Sharon Choi, Natalia C Gutierrez, Zafar S Gill, Kenneth Kim, Jefferson M Dang, Tanveer Salim, Marc Levis-Fitzgerald, Dan Huynh, Joyce Wang, Marsha R Cheng, Lillian Xie, Hannah Markovic, Conny Tran, Mimi Chiang, Vivian Lam, Nick Waite, Ricardo Gray, Jo M Huang

Publikováno v: G3: Genes|Genomes|Genetics

Undergraduate students participating in the UCLA Undergraduate Research Consortium for Functional Genomics (URCFG) have conducted a two-phased screen using RNA interference (RNAi) in combination with fluorescent reporter proteins to identify genes im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4805eb5e0282ec70c30a10873c70b2c5
https://doi.org/10.1093/g3journal/jkaa028

Injury-induced inflammatory signaling and hematopoiesis in

Autor: Cory J, Evans, Ting, Liu, Juliet R, Girard, Utpal, Banerjee

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 119(12)

Inflammatory response in Drosophila to sterile (axenic) injury in embryos and adults has received some attention in recent years, and most concentrate on the events at the injury site. Here we focus on the effect sterile injury has on the hematopoiet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::082339ff0b0092effcece049297abe3b
https://pubmed.ncbi.nlm.nih.gov/35286208

The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair

Autor: Yijie Wang, Matteo Pellegrini, Robert Damoiseaux, Thomas G. Graeber, Yen-Ju Lin, Marcus M. Seldin, Ilya Gertsman, Abraham Rodriguez, Pei-Yu Chiou, Johanna ten Hoeve, Thuc Le, Rimao Wu, Evan R. Abt, Aldons J. Lusis, Caius G. Radu, Michael A. Teitell, Kym F. Faull, Shen Li, Yonggang Zhou, Ping Wang, Vicky E MacRae, Tomohiro Yokota, Arjun Deb, Michael E. Jung, Steven J. Bensinger, Demetrios T. Braddock, Utpal Banerjee, Maxine Nanthavongdouangsy, Hayato Muranaka, Feiyang Ma, Mark S. Sharpley, Dian Huang

Publikováno v: Li, S, Yokota, T, Wang, P, Ten Hoeve, J, Ma, F, Le, T M, Abt, E R, Zhou, Y, Wu, R, Nanthavongdouangsy, M, Rodriguez, A, Wang, Y, Lin, Y-J, Muranaka, H, Sharpley, M, Braddock, D T, MacRae, V E, Banerjee, U, Chiou, P-Y, Seldin, M, Huang, D, Teitell, M, Gertsman, I, Jung, M, Bensinger, S J, Damoiseaux, R, Faull, K, Pellegrini, M, Lusis, A, Graeber, T G, Radu, C G & Deb, A 2021, ' The cardiomyocyte disrupts pyrimidine biosynthesis in non-myocytes to regulate heart repair ', Journal of Clinical Investigation . https://doi.org/10.1172/JCI149711
The Journal of clinical investigation, vol 132, iss 2
The Journal of Clinical Investigation

Various populations of cells are recruited to the heart after cardiac injury, but little is known about whether cardiomyocytes directly regulate heart repair. Using a murine model of ischemic cardiac injury, we demonstrate that cardiomyocytes play a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5980f301979e0b1b2decd77e28a2125d
https://hdl.handle.net/20.500.11820/4aa0a3c1-d1a8-4c5a-a61d-f8fe256d84ff