Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Uthaman, Gowthaman"'
Autor:
Zhang, Biyan, Chen, Shuting, Yin, Xiangyun, McBride, Caleb D., Gertie, Jake A., Yurieva, Marina, Bielecka, Agata A., Hoffmann, Brian, Travis Hinson, J., Grassmann, Jessica, Xu, Lan, Siniscalco, Emily R., Soldatenko, Arielle, Hoyt, Laura, Joseph, Julie, Norton, Elizabeth B., Uthaman, Gowthaman, Palm, Noah W., Liu, Elise, Eisenbarth, Stephanie C., Williams, Adam
Publikováno v:
In Mucosal Immunology June 2024 17(3):431-449
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:1050-1052
Autor:
Samuele Calabro, Dong Liu, Antonia Gallman, Manuela Sales L. Nascimento, Zizi Yu, Ting-ting Zhang, Pei Chen, Biyan Zhang, Lan Xu, Uthaman Gowthaman, Jayendra Kumar Krishnaswamy, Ann M. Haberman, Adam Williams, Stephanie C. Eisenbarth
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2472-2485 (2016)
Evidence suggests that distinct splenic dendritic cell (DC) subsets activate either CD4+ or CD8+ T cells in vivo. This bias has been partially ascribed to differential antigen presentation; however, all DC subsets can activate both T cell lineages in
Externí odkaz:
https://doaj.org/article/7b47bcf2e3504b8c9d1102cb16b8d552
Autor:
Adam Williams, Stephanie C. Eisenbarth, Lan Xu, Biyan Zhang, Lauren L. Long, Jake A. Gertie, Laura R. Hoyt, Uthaman Gowthaman, Xiangyun Yin, Elise G. Liu, Arielle Soldatenko
Publikováno v:
J Allergy Clin Immunol
Background The etiology of food allergy is poorly understood; mouse models are powerful systems to discover immunologic pathways driving allergic disease. C3H/HeJ mice are a widely used model for the study of peanut allergy because, unlike C57BL/6 or
Publikováno v:
The Journal of allergy and clinical immunology. 150(5)
Autor:
Jessica D.S. Grassmann, Tregony Simoneau, Stephanie C. Eisenbarth, Sam J. Olyha, Jennifer S. Chen, Uthaman Gowthaman, Adam Williams, M. Cecilia Berin
Publikováno v:
Journal of Allergy and Clinical Immunology. 147:470-483
Anaphylaxis is a life-threatening allergic reaction caused by cross-linking of high-affinity IgE antibodies on the surface of mast cells and basophils. Understanding the cellular mechanisms that lead to high-affinity IgE production is required to dev
Publikováno v:
J Leukoc Biol
Allergies to food and environmental antigens have steeply grown to epidemic proportions. IgE antibodies are key mediators of allergic disease, including life-threatening anaphylaxis. There is now compelling evidence that one of the hallmarks of anaph
Autor:
Jennifer S. Chen, Ryan D. Chow, Eric Song, Tianyang Mao, Benjamin Israelow, Kathy Kamath, Joel Bozekowski, Winston A. Haynes, Renata B. Filler, Bridget L. Menasche, Jin Wei, Mia Madel Alfajaro, Wenzhi Song, Lei Peng, Lauren Carter, Jason S. Weinstein, Uthaman Gowthaman, Sidi Chen, Joe Craft, John C. Shon, Akiko Iwasaki, Craig B. Wilen, Stephanie C. Eisenbarth
Publikováno v:
Sci Immunol
T follicular helper (T FH ) cells are the conventional drivers of protective, germinal center (GC)–based antiviral antibody responses. However, loss of T FH cells and GCs has been observed in patients with severe COVID-19. As T cell–B cell intera
Publikováno v:
Trends Parasitol
Immunity
Immunity
Cryptosporidium can cause severe diarrhea and morbidity, but many infections are asymptomatic. Here, we studied the immune response to a commensal strain of Cryptosporidium tyzzeri (Ct-STL) serendipitously discovered when conventional type 1 dendriti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e7852b5245be270822c47c264b68ba
https://europepmc.org/articles/PMC9576149/
https://europepmc.org/articles/PMC9576149/
Publikováno v:
Current opinion in immunology. 74
T follicular helper (Tfh) cells help orchestrate optimal humoral immunity by helping B cells to produce affinity-matured, class-switched antibodies in germinal centers. Recent studies have unveiled the complexity and heterogeneity in Tfh cell populat