Zobrazeno 1 - 10
of 1 591
pro vyhledávání: '"Uterine leiomyosarcoma"'
Autor:
Jordi Gonzalez‐Molina, Paula Hahn, Raul Maia Falcão, Okan Gultekin, Georgia Kokaraki, Valentina Zanfagnin, Tirzah Braz Petta, Kaisa Lehti, Joseph W. Carlson
Publikováno v:
Molecular Oncology, Vol 18, Iss 4, Pp 850-865 (2024)
Fibrillar collagen deposition, stiffness and downstream signalling support the development of leiomyomas (LMs), common benign mesenchymal tumours of the uterus, and are associated with aggressiveness in multiple carcinomas. Compared with epithelial c
Externí odkaz:
https://doaj.org/article/ce0b7c7310a54a3d94cc48e84d821fb1
Autor:
Wout De Wispelaere, Daniela Annibali, Sandra Tuyaerts, Julie Messiaen, Asier Antoranz, Gautam Shankar, Nikolina Dubroja, Alejandro Herreros‐Pomares, Regina E. M. Baiden‐Amissah, Marie‐Pauline Orban, Marcello Delfini, Emanuele Berardi, Thomas Van Brussel, Rogier Schepers, Gino Philips, Bram Boeckx, Maria Francesca Baietti, Luigi Congedo, Kiave Yune HoWangYin, Emilie Bayon, Anne‐Sophie Van Rompuy, Eleonora Leucci, Sebastien P. Tabruyn, Francesca Bosisio, Massimiliano Mazzone, Diether Lambrechts, Frédéric Amant
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Uterine leiomyosarcomas (uLMS) are aggressive tumours with poor prognosis and limited treatment options. Although immune checkpoint blockade (ICB) has proven effective in some ‘challenging‐to‐treat’ cancers, clinical trial
Externí odkaz:
https://doaj.org/article/96c1f251d0ff4741b236139055f4119b
Publikováno v:
Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, Vol 18, Iss 3, Pp 195-202 (2023)
Usnic acid (UA) is a common lichenic secondary metabolite with therapeutic potential. Anticancer, antimicrobial, and antioxidant effects have been demonstrated and UA-enriched extracts are often used to treat various diseases in traditional medicine.
Externí odkaz:
https://doaj.org/article/e98ab82f000549b4ad6c9f2f89643325
Publikováno v:
Cells, Vol 13, Iss 17, p 1443 (2024)
Uterine leiomyosarcoma (uLMS) is the most common type of uterine sarcoma, associated with poor prognosis, high rates of recurrence, and metastasis. Currently, the molecular mechanism of the origin and development of uLMS is limited. Bromodomain and e
Externí odkaz:
https://doaj.org/article/5645efaaa8624612a6e767075703824a
Autor:
Jinhua Huang, Yu Chen, Ziyin Li, Mimi Chen, Dingwen Huang, Peixin Zhu, Xintong Han, Yi Zheng, Xiaochun Chen, Zhiying Yu
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundUterine leiomyosarcoma(uLMS) is a rare malignant tumor with low clinical specificity and poor prognosis.There are many studies related to uLMS, however, there is still a lack of metrological analyses with generalization. This study provides
Externí odkaz:
https://doaj.org/article/b0240b7256d24691a98dc68bc7e1d1b8
Publikováno v:
Gynecologic Oncology Reports, Vol 51, Iss , Pp 101326- (2024)
Uterine leiomyosarcomas (ULMS) are a rare cause of uterine malignancy. Due to their aggressive nature, resistance to standard therapy and high rates of recurrence, they are associated with a very poor prognosis, irrespective of their stage at diagnos
Externí odkaz:
https://doaj.org/article/f4607740b8d348f890c6ce5235753569
Autor:
Brian K. Sparkman, Janina Pearce, Katherine Klein, Michael Idowu, Koorosh Askari, Leopoldo J. Fernandez, Jose G. Trevino, Stephanie A. Sullivan, Devin T. Miller, Leslie M. Randall
Publikováno v:
Gynecologic Oncology Reports, Vol 51, Iss , Pp 101306- (2024)
Externí odkaz:
https://doaj.org/article/02a76c11bde2449ab9ec28c41a4fadb7
Autor:
Iqra Ijaz, Muhammad Naveed Shahzad, Hossein Hosseinifard, Shuya Liu, Masoud Ostadi Sefidan, Lubna Ejaz Kahloon, Saber Imani, Zhong Hua, Yu Qin Zhang
Publikováno v:
Cancer Medicine, Vol 12, Iss 13, Pp 13894-13911 (2023)
Abstract Uterine leiomyosarcoma (uLMS) is an aggressive mesenchymal neoplasm associated with a poor prognosis. Systemic chemotherapy is the standard therapy for patients with uLMS. However, it is unclear which treatment regimen results in the most fa
Externí odkaz:
https://doaj.org/article/a7d011288d2149b5b3d0fab47e952e4e
Autor:
Qiwei Yang, Obianuju Sandra Madueke-Laveaux, Han Cun, Marta Wlodarczyk, Natalia Garcia, Katia Candido Carvalho, Ayman Al-Hendy
Publikováno v:
Cells, Vol 13, Iss 13, p 1106 (2024)
Uterine leiomyosarcoma (uLMS) is the most common subtype of uterine sarcomas. They have a poor prognosis with high rates of recurrence and metastasis. The five-year survival for uLMS patients is between 25 and 76%, with survival rates approaching 10
Externí odkaz:
https://doaj.org/article/b3c202554f44401ab7efdbea6557536b
Autor:
Yasmin Abedin, Alexander Fife, Cherie-Ann Samuels, Rasheena Wright, Trystn Murphy, Xusheng Zhang, Emily Alpert, Emma Cheung, Qingshi Zhao, Mark H. Einstein, Nataki C. Douglas
Publikováno v:
Cancers, Vol 16, Iss 12, p 2184 (2024)
Due to limited effective therapeutics for uterine leiomyosarcoma (uLMS), the impact of the gamma secretase inhibitor (GSI) MK-0752 with common chemotherapeutics was explored in uLMS. MTT assays were performed on two human uLMS cell lines, SK-UT-1B an
Externí odkaz:
https://doaj.org/article/af6454595235444793226392f65e5c86