Role of pre-transplant MRD level detected by flow cytometry in recipients of allogeneic stem cell transplantation with AML

Autor: Ute-Marie von Pein, Ulrike Bacher, Ulrike Fritzsche-Friedland, Maximilian Christopeit, Anita Badbaran, Nicolaus Kröger, Evgeny Klyuchnikov, Christine Wolschke

Publikováno v: Klyuchnikov, Evgeny; Christopeit, Maximilian; Badbaran, Anita; Bacher, Ulrike; Fritsche-Friedland, Ulrike; von Pein, Ute-Marie; Wolschke, Christine; Kröger, Nicolaus (2021). Role of pre-transplant MRD level detected by flow cytometry in recipients of allogeneic stem cell transplantation with AML. European journal of haematology, 106(5), pp. 606-615. Wiley-Blackwell 10.1111/ejh.13557

OBJECTIVES AND METHODS We analyzed the impact of pretransplant MRD level in bone marrow measured by flow cytometry using "different from normal" method on outcomes for 189 AML patients (108 males; median age, 58 (21-80) years). All patients were subd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb6e375691d332924180b593af72efc
https://boris.unibe.ch/149533/1/Role_of_pre-transplant_MRD.pdf

Correction: Ruxolitinib plus extracorporeal photopheresis (ECP) for steroid refractory acute graft-versus-host disease of lower GI-tract after allogeneic stem cell transplantation leads to increased regulatory T cell level

Autor: Francis Ayuk, Franziska Modemann, Dietlinde Janson, Christine Wolschke, Ute-Marie von Pein, Nicolaus Kröger, Maximilian Christopeit

Publikováno v: Bone Marrow Transplantation

Acute graft-versus-host disease (aGVHD) is a serious complication after stem cell transplantation and is associated with high non-relapse mortality. If steroid treatment as first-line therapeutic approach fails, treatment options are limited. In retr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3bcf31fe9a981759e55d9a04cc1534
http://europepmc.org/articles/PMC8486666

Allogeneic stem cell transplantation for myelofibrosis patients aged ≥65 years

Autor: Christine Wolschke, Francis Ayuk, Ute-Marie von Pein, Nicolaus Kröger, Maximilian Christopeit, Giulia Daghia, Tatjana Zabelina, Gaby Zeck

Publikováno v: European journal of haematologyREFERENCES. 103(4)

Introduction Myelofibrosis (MF) is a disease of elderly with median age of 65 years at diagnosis. Allogeneic stem cell transplantation (ASCT) currently is the only potentially curative option, although associated with treatment-related morbidity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9763df057641eaa29f4bb63b622f67f9
https://pubmed.ncbi.nlm.nih.gov/31306511

Reduced Intensity Allogeneic Stem Cell Transplantation for Younger Patients with Myelofibrosis

Autor: Daniele Mannina, Tatjana Zabelina, Nicolaus Kroeger, Francis Ayuk, Gaby Zeck, Ute-Marie von Pein, Christine Wolschke

Publikováno v: Blood. 132:5783-5783

INTRODUCTION Allogeneic stem cell transplantation (alloSCT) is the only curative procedure for primary and secondary myelofibrosis (PMF, SMF). Elderly people are mainly affected, limiting the feasibility of intensive myeloablative chemotherapy regime

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b5c8040f75613f09e320bbf10c9a377
https://doi.org/10.1182/blood-2018-99-112137

Daratumumab Is an Effective and Safe Salvage Therapy in Relapsed/Refractory Patients with Multiple Myeloma after Allogeneic Stem Cell Transplantation

Autor: Evgeny Klyuchnikov, Ute-Marie von Pein, Andre van Randenborgh, Nicolaus Kröger, Christine Wolschke, Francis Ayuk, Maximilian Christopeit, Raissa Adjallé

Publikováno v: Blood. 128:3437-3437

Daratumumab is a human monoclonal antibody that targets CD38, a cell surface protein that is overexpressed on multiple myeloma cells. Some clinical studies have shown encouraging efficacy and acceptable safety profile of daratumumab, so that the drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::829f2c8a62924403f268909d28043dac
https://doi.org/10.1182/blood.v128.22.3437.3437