Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ute Weyen"'
Autor:
Susanne Spittel, Thomas Meyer, Ute Weyen, Torsten Grehl, Patrick Weydt, Robert Steinbach, Susanne Petri, Petra Baum, Moritz Metelmann, Anne-Dorte Sperfeld, Dagmar Kettemann, Jenny Norden, Annekathrin Rödiger, Benjamin Ilse, Julian Grosskreutz, Barbara Hildebrandt, Bertram Walter, Christoph Münch, André Maier
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-12 (2024)
Abstract Objective Robotic arms are innovative assistive devices for ALS patients with progressive motor deficits of arms and hands. The objective was to explore the patients´ expectations towards a robotic arm system and to assess the actual experi
Externí odkaz:
https://doaj.org/article/80803eee5f02475e924a6ea4a09d7a46
Autor:
Jochen H. Weishaupt, Péter Körtvélyessy, Peggy Schumann, Ivan Valkadinov, Ute Weyen, Jasper Hesebeck-Brinckmann, Kanchi Weishaupt, Matthias Endres, Peter M. Andersen, Martin Regensburger, Marie Dreger, Jan C. Koch, Julian Conrad, Thomas Meyer
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-5 (2024)
Abstract Background Since the antisense oligonucleotide tofersen has recently become available for the treatment of amyotrophic lateral sclerosis (ALS) caused by mutations in SOD1, determining the causality of the over 230 SOD1 variants has become ev
Externí odkaz:
https://doaj.org/article/6dd37b8edbb149059b7df64c953bc24a
Autor:
Katharina Linse, Constanze Weber, Peter Reilich, Florian Schöberl, Matthias Boentert, Susanne Petri, Annekathrin Rödiger, Andreas Posa, Markus Otto, Joachim Wolf, Daniel Zeller, Robert Brunkhorst, Jan Koch, Andreas Hermann, Julian Großkreutz, Carsten Schröter, Martin Groß, Paul Lingor, Gerrit Machetanz, Luisa Semmler, Johannes Dorst, Dorothée Lulé, Albert Ludolph, Thomas Meyer, André Maier, Moritz Metelmann, Martin Regensburger, Jürgen Winkler, Berthold Schrank, Zacharias Kohl, Tim Hagenacker, Svenja Brakemeier, Ute Weyen, Markus Weiler, Stefan Lorenzl, Sarah Bublitz, Patrick Weydt, Torsten Grehl, Sylvia Kotterba, Hanna-Sophie Lapp, Maren Freigang, Maximilian Vidovic, Elisa Aust, René Günther
Publikováno v:
Neurological Research and Practice, Vol 6, Iss 1, Pp 1-8 (2024)
Abstract Introduction Amyotrophic lateral sclerosis (ALS) is an inevitably fatal condition that leads to a progressive loss of physical functioning, which results in a high psychosocial burden and organizational challenges related to medical care. Mu
Externí odkaz:
https://doaj.org/article/c0f478ca254b44ff867cfc78aad679ea
Autor:
Xiaoyan Wang, Patrick Julian Klann, Ellen Wiedtke, Yumi Sano, Nico Fischer, Lisa Schiller, Anna Elfert, Anne-Katrin Güttsches, Ute Weyen, Dirk Grimm, Matthias Vorgerd, Wibke Bayer
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
High levels of pre-existing antibodies are a major challenge for the application of viral vectors since they can severely limit their efficacy. To identify promising candidates among adeno-associated virus (AAV) based vectors for future gene therapie
Externí odkaz:
https://doaj.org/article/678bdd0209ea4d16bd2e41790c7c76a6
Autor:
Maximilian Wiesenfarth, Johannes Dorst, David Brenner, Zeynep Elmas, Özlem Parlak, Zeljko Uzelac, Katharina Kandler, Kristina Mayer, Ulrike Weiland, Christine Herrmann, Joachim Schuster, Axel Freischmidt, Kathrin Müller, Reiner Siebert, Franziska Bachhuber, Tatiana Simak, Kornelia Günther, Elke Fröhlich, Antje Knehr, Martin Regensburger, Alexander German, Susanne Petri, Julian Grosskreutz, Thomas Klopstock, Peter Reilich, Florian Schöberl, Tim Hagenacker, Ute Weyen, René Günther, Maximilian Vidovic, Martin Jentsch, Thomas Haarmeier, Patrick Weydt, Ivan Valkadinov, Jasper Hesebeck-Brinckmann, Julian Conrad, Jochen Hans Weishaupt, Peggy Schumann, Peter Körtvélyessy, Thomas Meyer, Wolfgang Philipp Ruf, Simon Witzel, Makbule Senel, Hayrettin Tumani, Albert Christian Ludolph
Publikováno v:
EClinicalMedicine, Vol 69, Iss , Pp 102495- (2024)
Summary: Background: In April 2023, the antisense oligonucleotide tofersen was approved by the U.S. Food and Drug Administration (FDA) for treatment of SOD1-amyotrophic lateral sclerosis (ALS), after a decrease of neurofilament light chain (NfL) leve
Externí odkaz:
https://doaj.org/article/e3789dbd542444e5a7333ffea39056d9
Autor:
André Maier, Marcel Gaudlitz, Torsten Grehl, Ute Weyen, Robert Steinbach, Julian Grosskreutz, Annekathrin Rödiger, Jan Christoph Koch, Teresa Lengenfeld, Patrick Weydt, René Günther, Joachim Wolf, Petra Baum, Moritz Metelmann, Johannes Dorst, Albert C. Ludolph, Dagmar Kettemann, Jenny Norden, Ruhan Yasemin Koc, Bertram Walter, Barbara Hildebrandt, Christoph Münch, Thomas Meyer, Susanne Spittel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Motor-assisted movement exercisers (MME) are devices that assist with physical therapy in domestic settings for people living with ALS. This observational cross-sectional study assesses the subjective experience of the therapy and analyzes u
Externí odkaz:
https://doaj.org/article/dae52e8c7c1148c0af7cde27ad70d10c
Autor:
Patrick Julian Klann, Xiaoyan Wang, Anna Elfert, Wenli Zhang, Cornelia Köhler, Anne-Katrin Güttsches, Frank Jacobsen, Ute Weyen, Andreas Roos, Eric Ehrke-Schulz, Anja Ehrhardt, Matthias Vorgerd, Wibke Bayer
Publikováno v:
Viruses, Vol 15, Iss 1, p 79 (2022)
High pre-existing antibodies against viral vectors reduce their functionality and may lead to adverse complications. To circumvent this problem in future gene therapy approaches, we tested the seroprevalence of a large range of human adenovirus types
Externí odkaz:
https://doaj.org/article/70af1f19e10f48d9b271a683077bc16f
Autor:
Pavel Schischlevskij, Isabell Cordts, René Günther, Benjamin Stolte, Daniel Zeller, Carsten Schröter, Ute Weyen, Martin Regensburger, Joachim Wolf, Ilka Schneider, Andreas Hermann, Moritz Metelmann, Zacharias Kohl, Ralf A. Linker, Jan Christoph Koch, Claudia Stendel, Lars H. Müschen, Alma Osmanovic, Camilla Binz, Thomas Klopstock, Johannes Dorst, Albert C. Ludolph, Matthias Boentert, Tim Hagenacker, Marcus Deschauer, Paul Lingor, Susanne Petri, Olivia Schreiber-Katz
Publikováno v:
Brain Sciences, Vol 11, Iss 6, p 748 (2021)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes progressive autonomy loss and need for care. This does not only affect patients themselves, but also the patients’ informal caregivers (CGs) in their health, perso
Externí odkaz:
https://doaj.org/article/97ac8e0413094a19b6607ae2bbfe92c6
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Background: Given the lethal severity of amyotrophic lateral sclerosis (ALS), the aim of this study was to illuminate the coherence of depression and death anxiety in both ALS patients and caregivers and in how far patients and caregivers are influen
Externí odkaz:
https://doaj.org/article/fd3e327d8869412792b918a2f0d76bcc
Autor:
Tara Peseschkian, Isabell Cordts, René Günther, Benjamin Stolte, Daniel Zeller, Carsten Schröter, Ute Weyen, Martin Regensburger, Joachim Wolf, Ilka Schneider, Andreas Hermann, Moritz Metelmann, Zacharias Kohl, Ralf A. Linker, Jan Christoph Koch, Boriana Büchner, Ulrike Weiland, Erik Schönfelder, Felix Heinrich, Alma Osmanovic, Thomas Klopstock, Johannes Dorst, Albert C. Ludolph, Matthias Boentert, Tim Hagenacker, Marcus Deschauer, Paul Lingor, Susanne Petri, Olivia Schreiber-Katz
Publikováno v:
Brain Sciences, Vol 11, Iss 3, p 372 (2021)
Improving quality of life (QoL) is central to amyotrophic lateral sclerosis (ALS) treatment. This Germany-wide, multicenter cross-sectional study analyses the impact of different symptom-specific treatments and ALS variants on QoL. Health-related QoL
Externí odkaz:
https://doaj.org/article/fdc18fe43d044d80b6d0439741861dc2