Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ute Staar"'
Publikováno v:
Biochemical Pharmacology. 40:1997-2003
The effects of the anti-inflammatory seleno-organic compound ebselen on gastric H+/K(+)-ATPase, H+/K(+)-ATPase-mediated proton transport and on parietal cell HCl production was studied. Ebselen inhibited K(+)-stimulated ATPase activity in leaky gastr
Publikováno v:
European journal of pharmacology. 218(2-3)
The action of the H+/K(+)-ATPase inhibitors pantoprazole and omeprazole was compared in different in vitro test systems. In gastric membrane vesicles under conditions shown to result in acidification of the vesicle interior, pantoprazole and omeprazo
Publikováno v:
European journal of pharmacology. 187(3)
The action of the H+/K(+)-ATPase inhibitors, Hoe 731 and S 4216, both thieno-imidazole derivatives, was compared with that of the benzimidazole derivative, omeprazole. In intact, gastric membrane vesicles under conditions shown to result in acidifica
Publikováno v:
Biochemical Pharmacology. 37:843-848
The inhibitory effects of omeprazole and omeprazole-derived metabolites were studied on Escherichia coli glutaminase activity at pH 2.5 which might represent the conditions present at the target enzyme (K + /H + -ATPase) in the secretory membrane of
Publikováno v:
Biochemical Pharmacology. 37:4487-4493
The effects of omeprazole, SCH 28080 and doxepin were studied on H+/K+-ATPase mediated H+ accumulation in parietal cell membrane vesicles. Omeprazole had no effect on the initial rate of H+ accumulation and the initial steady state concentration of H
Publikováno v:
European Journal of Pharmacology. 147:217-226
[3H]Prostaglandin E2 (PGE2) binding sites were 10-fold enriched from a porcine fundic mucosal homogenate by differential centrifugation and subsequent discontinuous sucrose gradient separation. PGE2 bound with an activation energy of 66 kJ/mol to a s
Publikováno v:
European journal of pharmacology. 139(3)
The anti-secretory agents SCH 32651 and SCH 28080 were compared for their potency to interact with the K + site of guinea-pig parietal cell K + /H + -ATPase and dog kidney Na + /K + -ATPase. SCH 32651 and SCH 28080 had an inhibition constant of 9.0 a