Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ute M. Liegibel"'
Publikováno v:
Biochemical and Biophysical Research Communications. 389:550-555
Purpose Osteoprotegerin (OPG) affects bone metabolism by intercepting the RANK–RANKL interaction which prevents osteoclastic differentiation and consequently reduces bone resorption. Different bone phenotypes of mice overexpressing OPG and of mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d166c6b293d76e86ed0fa3daa7ad36a8
https://doi.org/10.1016/j.bbrc.2009.09.026
https://doi.org/10.1016/j.bbrc.2009.09.026
Autor:
Triantafyllos Chavakis, Usha R. Pendurthi, Christian Kasperk, Peter P. Nawroth, Darius Schneider, Athanasios N. Athanasopoulos, Volker Alt, U. Sommer, Tanja Keiper, Ute M. Liegibel
Publikováno v:
Journal of Biological Chemistry. 282:26746-26753
Angiogenesis is indispensable during fracture repair, and vascular endothelial growth factor (VEGF) is critical in this process. CCN1 (CYR61) is an extracellular matrix signaling molecule that has been implicated in neovascularization through its int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801a9f37436682ac77cbae2325f9bd61
https://doi.org/10.1074/jbc.m705200200
https://doi.org/10.1074/jbc.m705200200
Autor:
Christian Kasperk, Martin Libicher, U. Sommer, Gerd Nöldge, Walter Pyerin, I. Grafe, Hans-Peter Meinzer, Peter P. Nawroth, J. Hillmeier, P. J. Meeder, M. Vetter, Ute M. Liegibel
Publikováno v:
Osteoporosis International. 17:1208-1215
This study evaluated the radiological changes at the bone–cement interface of calcium phosphate cement (CPC) and polymethylmethacrylate (PMMA) 12 months after kyphoplasty. In a pilot experiment, we additionally performed a histomorphometric analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0448a06bf963c9ece299bc0180afa1
https://doi.org/10.1007/s00198-006-0128-8
https://doi.org/10.1007/s00198-006-0128-8
Autor:
I. Grafe, Tilly N, Peter P. Nawroth, Rainer Pirzer, Ute M. Liegibel, U. Sommer, Christian Kasperk
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 113:598-601
A locally accelerated bone turnover is the pathophysiological basis of Paget's disease of bone (PD) and may result in severe bone deformations and pain. Affected bone sites are hypervascularized. Secreted endothelial products such as endothelin-1 (ET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c959661b1afe97c8b795de23070988
https://doi.org/10.1055/s-2005-872905
https://doi.org/10.1055/s-2005-872905
Autor:
Ute M. Liegibel, Ulrike Hilscher, Christian Kasperk, H. U. Schweikert, Peter P. Nawroth, Angelika Bierhaus, Irma Boercsoek, U. Sommer
Publikováno v:
Steroids. 68:1179-1187
Two isoforms of the androgen receptor (AR-A and AR-B), differing by a lack of the first 187 amino acids in the NH2-terminal transactivation domain of AR-A, are expressed in connective tissue and bone. Transient transfections of normal human osteoblas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf461648812c01e003c88aff05c979b
https://doi.org/10.1016/j.steroids.2003.08.016
https://doi.org/10.1016/j.steroids.2003.08.016
Autor:
Ute M. Liegibel, Ulrike Hilscher, Peter P. Nawroth, Joachim Hillmeier, Christian Kasperk, U. Sommer, Loes van den Heuvel, Rainer Pirzer, Pascal Tomakidi
Publikováno v:
The Journal of Experimental Medicine
Adhesion of bone cells to the extracellular matrix is a crucial requirement for osteoblastic development and function. Adhesion receptors connect the extracellular matrix with the cyto-skeleton and convey matrix deformation into the cell. We tested t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf447a7601fd5dcc757c82d2ffdc17bf
http://europepmc.org/articles/PMC2193981
http://europepmc.org/articles/PMC2193981
Autor:
Véronique Thybaud, Nancy J. Gorelick, Terry Brooks, George R. Douglas, Takayoshi Suzuki, Barry H. Margolin, Joost H.M. van Delft, Ann C. Lockhart, Gregory J. Carr, Ute M. Liegibel, Walter W. Piegorsch
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 388:249-289
Experimental features of a positive selection transgenic mouse mutation assay based on a lambda lacZ transgene are considered in detail, with emphasis on results using germ cells as the target tissue. Sources of variability in the experimental protoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378183a8cce5a5b815b46ca5cba53687
https://doi.org/10.1016/s1383-5718(96)00123-4
https://doi.org/10.1016/s1383-5718(96)00123-4
Autor:
Christian Kasperk, Hilscher U, B. Bundschuh, U. Sommer, Schweizer B, Peter P. Nawroth, Lieder A, Ute M. Liegibel
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 112(7)
Deformation of the bone matrix by mechanical strain causes fluid shifts within the osteocytic canaliculi which affect osteocytic cell metabolism. We applied low fluid shear (1 - 63 micro Pa for 10 - 48 h) to human osteoblastic cells (HOB) in vitro to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7c8bade48a25b4003d6802722dcdfb
https://pubmed.ncbi.nlm.nih.gov/15239020
https://pubmed.ncbi.nlm.nih.gov/15239020
Autor:
Rod S Taylor, Walter Pyerin, Ute M. Liegibel, Marcus Vetter, K. DaFonseca, Peter P. Nawroth, Peter Jürgen Meeder, Ulrike Hilscher, Hubert J. Bardenheuer, I. Grafe, Christian Kasperk, Hans-Peter Meinzer, Martin Libicher, U. Sommer, Dorothea Raupp, J. Hillmeier, Gerd Nöldge
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 20(4)
This study investigates the effects of kyphoplasty on pain and mobility in patients with osteoporosis and painful vertebral fractures compared with conventional medical management. Introduction: Pharmacological treatment of patients with primary oste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990b67d4e119d28a50fdd466b0072484
https://pubmed.ncbi.nlm.nih.gov/15765179
https://pubmed.ncbi.nlm.nih.gov/15765179
Autor:
H. Müller, Achim Bub, Bernhard Watzl, Mark Blockhaus, Gerhard Rechkemmer, Karlis Briviba, Beatrice L. Pool-Zobel, Ute M. Liegibel
Publikováno v:
The Journal of nutritional biochemistry. 14(2)
Polyphenolic compounds exert a variety of physiological effects in vitro including antioxidative, immunomodulatory and antigenotoxic effects. In a randomized crossover study in healthy men on a low-polyphenol diet, we determined the effects of 2 poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97278b7ef8e428328fd8fbd5fda5440d
https://pubmed.ncbi.nlm.nih.gov/12667600
https://pubmed.ncbi.nlm.nih.gov/12667600