Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Ute Hochgeschwender"'
Autor:
Mansi Prakash, Jeremy Murphy, Robyn St Laurent, Nina Friedman, Emmanuel L. Crespo, Andreas Bjorefeldt, Akash Pal, Yuvraj Bhagat, Julie A. Kauer, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Prakash et al. develop an approach to control synaptically connected elements using bioluminescent light, in which Luciferase-generated light, originating from a presynaptic axon terminal, modulates an opsin in its postsynaptic target to form an ‘o
Externí odkaz:
https://doaj.org/article/466740bf581a4a9e9e4cf7688016fe99
Autor:
Eric D. Petersen, Erik D. Sharkey, Akash Pal, Lateef O. Shafau, Jessica Zenchak-Petersen, Alex J. Peña, Anu Aggarwal, Mansi Prakash, Ute Hochgeschwender
Publikováno v:
Frontiers in Neurology, Vol 12 (2022)
The ability to manipulate specific neuronal populations of the spinal cord following spinal cord injury (SCI) could prove highly beneficial for rehabilitation in patients through maintaining and strengthening still existing neuronal connections and/o
Externí odkaz:
https://doaj.org/article/c6ec47f021a347ae8a0141fc29f29613
Autor:
Emmanuel L. Crespo, Mansi Prakash, Andreas Bjorefeldt, William E. Medendorp, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100667- (2021)
Summary: Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically ta
Externí odkaz:
https://doaj.org/article/3c21176793034b0dae2223b29eebc3f3
Autor:
Ebenezer C. Ikefuama, Griffin E. Kendziorski, Kevin Anderson, Lateef Shafau, Mansi Prakash, Ute Hochgeschwender, Eric D. Petersen
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12994 (2022)
Irrespective of the many strategies focused on dealing with spinal cord injury (SCI), there is still no way to restore motor function efficiently or an adequate regenerative therapy. One promising method that could potentially prove highly beneficial
Externí odkaz:
https://doaj.org/article/c152378dad224d60b702492d347b367c
Autor:
Ashley R. Helseth, Arsen S. Hunanyan, Syed Adil, Molly Linabarger, Monisha Sachdev, Elie Abdelnour, Eric Arehart, Marlee Szabo, Jordan Richardson, William C. Wetsel, Ute Hochgeschwender, Mohamad A. Mikati
Publikováno v:
Neurobiology of Disease, Vol 119, Iss , Pp 100-112 (2018)
De novo mutations causing dysfunction of the ATP1A3 gene, which encodes the α3 subunit of Na+/K+-ATPase pump expressed in neurons, result in alternating hemiplegia of childhood (AHC). AHC manifests as paroxysmal episodes of hemiplegia, dystonia, beh
Externí odkaz:
https://doaj.org/article/66f13110be214ed7ba820e4483357442
Autor:
William E. Medendorp, Andreas Bjorefeldt, Emmanuel L. Crespo, Mansi Prakash, Akash Pal, Madison L. Waddell, Christopher I. Moore, Ute Hochgeschwender
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102157- (2021)
Summary: In genetic and pharmacological models of neurodevelopmental disorders, and human data, neural activity is altered within the developing neocortical network. This commonality begs the question of whether early enhancement in excitation might
Externí odkaz:
https://doaj.org/article/2fac34280f43468297b5619b71767bfc
Autor:
Srishti L. Bhagat, Sunny Qiu, Zachary F. Caffall, Yehong Wan, Yuanji Pan, Ramona M. Rodriguiz, William C. Wetsel, Alexandra Badea, Ute Hochgeschwender, Nicole Calakos
Publikováno v:
Neurobiology of Disease, Vol 93, Iss , Pp 137-145 (2016)
Rare de novo mutations in genes associated with inherited Mendelian disorders are potential contributors to sporadic disease. DYT1 dystonia is an autosomal dominant, early-onset, generalized dystonia associated with an in-frame, trinucleotide deletio
Externí odkaz:
https://doaj.org/article/1da28a4f412541dabad2ce9a9650e6e6
Autor:
William E. Medendorp, Eric D. Petersen, Akash Pal, Lina-Marie Wagner, Alexzander R. Myers, Ute Hochgeschwender, Kenneth A. Jenrow
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Mice socially isolated during adolescence exhibit behaviors of anxiety, depression and impaired social interaction. Although these behaviors are well documented, very little is known about the associated neurobiological changes that accompany these b
Externí odkaz:
https://doaj.org/article/c9964b2c0f28438c891ca4dd034bc26e
Autor:
Gabrielle Shall, Megan Menosky, Sarah Decker, Priya Nethala, Ryan Welchko, Xavier Leveque, Ming Lu, Michael Sandstrom, Ute Hochgeschwender, Julien Rossignol, Gary Dunbar
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 720 (2018)
Multiple studies have demonstrated the ability of mesenchymal stem cells (MSCs) to differentiate into dopamine-producing cells, in vitro and in vivo, indicating their potential to be used in the treatment of Parkinson’s disease (PD). However, there
Externí odkaz:
https://doaj.org/article/b0eb00423f954ec4a0e1858d227ac880
Autor:
Rui Dai, Ricardo Rossello, Chun-chun Chen, Joeran Kessler, Ian Davison, Ute Hochgeschwender, Erich D. Jarvis
Publikováno v:
Stem Cells International, Vol 2014 (2014)
Pluripotent stem cells have the potential to become any cell in the adult body, including neurons and glia. Avian stem cells could be used to study questions, like vocal learning, that would be difficult to examine with traditional mouse models. Indu
Externí odkaz:
https://doaj.org/article/ef8da76f227c4fe1a765e393b5265696