Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ute Häussler"'
Publikováno v:
Brain Stimulation, Vol 17, Iss 2, Pp 395-404 (2024)
Background: Mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) is a common form of drug-resistant focal epilepsy in adults. Treatment for pharmacoresistant patients remains a challenge, with deep brain stimulation (DBS) showing prom
Externí odkaz:
https://doaj.org/article/163d76e1da914a2582531922fa9a6666
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Selective loss of inhibitory interneurons (INs) that promotes a shift toward an excitatory predominance may have a critical impact on the generation of epileptic activity. While research on mesial temporal lobe epilepsy (MTLE) has mostly focused on h
Externí odkaz:
https://doaj.org/article/e874c5ffb1294368bf39a9c32f46fc8a
Autor:
Enya Paschen, Claudio Elgueta, Katharina Heining, Diego M Vieira, Piret Kleis, Catarina Orcinha, Ute Häussler, Marlene Bartos, Ulrich Egert, Philipp Janz, Carola A Haas
Publikováno v:
eLife, Vol 9 (2020)
Mesial temporal lobe epilepsy (MTLE) is the most common form of focal, pharmacoresistant epilepsy in adults and is often associated with hippocampal sclerosis. Here, we established the efficacy of optogenetic and electrical low-frequency stimulation
Externí odkaz:
https://doaj.org/article/19ab9a65b68149ae87c0d086008f586a
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Even in the adult mammalian brain progenitor cells proliferate and give rise to young neurons which integrate into the neuronal network. The dentate gyrus possesses such a neurogenic niche reactive to external stimuli like physical activity. In most
Externí odkaz:
https://doaj.org/article/9d116224a2104510badc842bb935e700
Autor:
Philipp Janz, Niels Schwaderlapp, Katharina Heining, Ute Häussler, Jan G Korvink, Dominik von Elverfeldt, Jürgen Hennig, Ulrich Egert, Pierre LeVan, Carola A Haas
Publikováno v:
eLife, Vol 6 (2017)
Mesial temporal lobe epilepsy (mTLE) is the most common focal epilepsy in adults and is often refractory to medication. So far, resection of the epileptogenic focus represents the only curative therapy. It is unknown whether pathological processes pr
Externí odkaz:
https://doaj.org/article/4208292b80424f77a070903b44484246
Autor:
Christophe Heinrich, Sari Lähteinen, Fumio Suzuki, Laharie Anne-Marie, Susanne Huber, Ute Häussler, Carola Haas, Yves Larmet, Eero Castren, Antoine Depaulis
Publikováno v:
Neurobiology of Disease, Vol 42, Iss 1, Pp 35-47 (2011)
Mesio-temporal lobe epilepsy (MTLE), the most common drug-resistant epilepsy syndrome, is characterized by the recurrence of spontaneous focal seizures after a latent period that follows, in most patients, an initial insult during early childhood. Ma
Externí odkaz:
https://doaj.org/article/7c3b6ca7791642d0a4c7e5d769fe08f8
Autor:
Aline Winkelmann, Xiantian You, Nora Grünewald, Ute Häussler, Heinz Krestel, Carola A Haas, Günter Schwarz, Wei Chen, Jochen C Meier
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125413 (2015)
Establishment of phylogenetic relationships remains a challenging task because it is based on computational analysis of genomic hot spots that display species-specific sequence variations. Here, we identify a species-specific thymine-to-guanine seque
Externí odkaz:
https://doaj.org/article/134482fdc3544c78be7f69958742c48e
Autor:
Enya Paschen, Piret Kleis, Diego M. Vieira, Katharina Heining, Christian Boehler, Ulrich Egert, Ute Häussler, Carola A. Haas
Mesial temporal lobe epilepsy (MTLE), the most common form of focal epilepsy in adults, is often refractory to medication and associated with hippocampal sclerosis. Deep brain stimulation represents an alternative treatment option for drug-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb1b5efe19fd4c6df3f90c86743e9b49
https://doi.org/10.1101/2023.04.17.537172
https://doi.org/10.1101/2023.04.17.537172
Autor:
Ute Häussler, João Neres, Catherine Vandenplas, Caroline Eykens, Irena Kadiu, Carolin Schramm, Renaud Fleurance, Phil Stanley, Patrice Godard, Laurane de Mot, Jonathan van Eyll, Klaus-Peter Knobeloch, Carola A. Haas, Stefanie Dedeurwaerdere
Structural epilepsies display complex immune activation signatures; however, it is unclear which neuroinflammatory pathways drive disease pathobiology. Transcriptome studies of brain resections from mesial temporal lobe epilepsy (mTLE) patients revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4335cefb20212e8fc9401815cd3fa9c1
https://doi.org/10.21203/rs.3.rs-2625841/v1
https://doi.org/10.21203/rs.3.rs-2625841/v1
Publikováno v:
HippocampusREFERENCES.
The CA2 pyramidal cells are mostly resistant to cell death in mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis, but they are aberrantly integrated into the epileptic hippocampal network via mossy fiber sprouting. Furthermore, they show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f8dfcc55de4f8672f4952c552b25cc
https://pubmed.ncbi.nlm.nih.gov/36421040
https://pubmed.ncbi.nlm.nih.gov/36421040