Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ute F Röhrig"'
Autor:
Ute F. Röhrig, Somi Reddy Majjigapu, Pierre Vogel, Aline Reynaud, Florence Pojer, Nahzli Dilek, Patrick Reichenbach, Kelly Ascenção, Melita Irving, George Coukos, Olivier Michielin, Vincent Zoete
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1773-1811 (2022)
The haem enzyme indoleamine 2,3-dioxygenase 1 (IDO1) catalyses the rate-limiting step in the kynurenine pathway of tryptophan metabolism and plays an essential role in immunity, neuronal function, and ageing. Expression of IDO1 in cancer cells result
Externí odkaz:
https://doaj.org/article/cf28d46a56e84bc6b249d5272612f6f4
Publikováno v:
Journal of medicinal chemistry, vol. 64, no. 24, pp. 17690-17705
Since the discovery of the implication of indoleamine 2,3-dioxygenase 1 (IDO1) in tumoral immune resistance in 2003, the search for inhibitors has been intensely pursued both in academia and in pharmaceutical companies, supported by the publication o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130a935d84363adbfa69160f76414e97
https://doi.org/10.1021/acs.jmedchem.1c01665
https://doi.org/10.1021/acs.jmedchem.1c01665
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618547
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86d6539da59199bf64dda04f8e1cbf2f
https://doi.org/10.1007/978-1-0716-1855-4_13
https://doi.org/10.1007/978-1-0716-1855-4_13
Autor:
Otavia L Caballero, Qi Zhao, Donata Rimoldi, Brian J Stevenson, Suzanne Svobodová, Sylvie Devalle, Ute F Röhrig, Anna Pagotto, Olivier Michielin, Daniel Speiser, Jedd D Wolchok, Cailian Liu, Tanja Pejovic, Kunle Odunsi, Francis Brasseur, Benoit J Van den Eynde, Lloyd J Old, Xin Lu, Jonathan Cebon, Robert L Strausberg, Andrew J Simpson
Publikováno v:
PLoS ONE, Vol 5, Iss 9, Pp 3307-3314 (2010)
BACKGROUND: Cancer/testis (CT) genes are expressed only in the germ line and certain tumors and are most frequently located on the X-chromosome (the CT-X genes). Amongst the best studied CT-X genes are those encoding several MAGE protein families. Th
Externí odkaz:
https://doaj.org/article/37fef53b5d7742bab7456b57d26a4314
Autor:
Somi Reddy Majjigapu, Ute F. Röhrig, Florence Pojer, Vincent Zoete, Aline Reynaud, Pierre Vogel
Publikováno v:
Journal of Medicinal Chemistry. 62:8784-8795
Indoleamine 2,3-dioxygenase 1 (IDO1) catalyzes the rate-limiting step in the kynurenine pathway of tryptophan metabolism, which is involved in immunity, neuronal function, and aging. Its implication in pathologies such as cancer and neurodegenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b6903d1c9a5a9df7200b9467e8e918
https://doi.org/10.1021/acs.jmedchem.9b00942
https://doi.org/10.1021/acs.jmedchem.9b00942
Publikováno v:
Nature Reviews Drug Discovery
L-Tryptophan (Trp) metabolism through the kynurenine pathway (KP) is involved in the regulation of immunity, neuronal function and intestinal homeostasis. Imbalances in Trp metabolism in disorders ranging from cancer to neurodegenerative disease have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0450baacbc937d0e254e705d2d4a1ab2
https://doi.org/10.1038/s41573-019-0016-5
https://doi.org/10.1038/s41573-019-0016-5
Publikováno v:
Systems Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ea03b2192b969c227a04b44adc26fa6
https://doi.org/10.1016/b978-0-12-801238-3.11670-8
https://doi.org/10.1016/b978-0-12-801238-3.11670-8
Autor:
Qi Wang, Laura J Byrnes, Bo Shui, Ute F Röhrig, Avtar Singh, Dmitriy M Chudakov, Sergey Lukyanov, Warren R Zipfel, Michael I Kotlikoff, Holger Sondermann
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23513 (2011)
Fluorescent proteins that can switch between distinct colors have contributed significantly to modern biomedical imaging technologies and molecular cell biology. Here we report the identification and biochemical analysis of a green-shifted red fluore
Externí odkaz:
https://doaj.org/article/eaf6abd054c74006af0981c4e88e0a13
Autor:
Otavia L. Caballero, Qi Zhao, Donata Rimoldi, Brian J. Stevenson, Suzanne Svobodová, Sylvie Devalle, Ute F. Röhrig, Anna Pagotto, Olivier Michielin, Daniel Speiser, Jedd D. Wolchok, Cailian Liu, Tanja Pejovic, Kunle Odunsi, Francis Brasseur, Benoit J. Van den Eynde, Lloyd J. Old, Xin Lu, Jonathan Cebon, Robert L. Strausberg, Andrew J. Simpson
Publikováno v:
PLoS ONE, Vol 5, Iss 11 (2010)
Externí odkaz:
https://doaj.org/article/0f9beb27778e421b8151de1aca4d0eb8
Autor:
Marc-Etienne Moret, Enrico Tapavicza, Leonardo Guidoni, Ute F. Röhrig, Marialore Sulpizi, Ivano Tavernelli, Ursula Rothlisberger
Publikováno v:
CHIMIA, Vol 59, Iss 7-8 (2005)
The combination of time-dependent density functional theory (TDDFT) for the description of excited states with a hybrid quantum mechanics/molecular mechanics (QM/MM) approach enables the study of photochemical processes in complex environments. Here,
Externí odkaz:
https://doaj.org/article/bc3255bc23b04e818cb1528ab5a3194a