Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ute, Becherer"'
Publikováno v:
BMC Biotechnology, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Cytotoxic T lymphocytes (CTLs) are central players in the adaptive immune response. Their functional characterization and clinical research depend on efficient and reliable transfection. Although various methods have been utilized
Externí odkaz:
https://doaj.org/article/46c396a92e2b470bac381393cbd4dea1
Autor:
Viktoria Götz, Sen Qiao, Debajyoti Das, Philipp Wartenberg, Amanda Wyatt, Vanessa Wahl, Igor Gamayun, Samer Alasmi, Claudia Fecher-Trost, Markus R. Meyer, Roland Rad, Thorsten Kaltenbacher, Kathrin Kattler, Peter Lipp, Ute Becherer, Patrice Mollard, Michael Candlish, Ulrich Boehm
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112543- (2023)
Summary: Gonadotropes in the anterior pituitary gland are essential for fertility and provide a functional link between the brain and the gonads. To trigger ovulation, gonadotrope cells release massive amounts of luteinizing hormone (LH). The mechani
Externí odkaz:
https://doaj.org/article/0f32d0856c444142996c0149f1fb9a46
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Regulated exocytosis is a central mechanism of cellular communication. It is not only the basis for neurotransmission and hormone release, but also plays an important role in the immune system for the release of cytokines and cytotoxic molecules. In
Externí odkaz:
https://doaj.org/article/86486fede6ac43a3891e5c025c5acbab
Autor:
Hsin-Fang Chang, Claudia Schirra, Momchil Ninov, Ulrike Hahn, Keerthana Ravichandran, Elmar Krause, Ute Becherer, Štefan Bálint, Maria Harkiolaki, Henning Urlaub, Salvatore Valitutti, Cosima T. Baldari, Michael L. Dustin, Reinhard Jahn, Jens Rettig
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cytotoxic T cells have specialised granules that are important for mediating their killing function. Here the authors characterise two types of cytotoxic granules and indicate different functions and temporal release of mediators at the immunological
Externí odkaz:
https://doaj.org/article/31a8c24e301a4df68584d46846ad161c
Autor:
Angelina Staudt, Olga Ratai, Aicha Bouzouina, Claudia Fecher-Trost, Ahmed Shaaban, Hawraa Bzeih, Alexander Horn, Ali H. Shaib, Margarete Klose, Veit Flockerzi, Marcel A. Lauterbach, Jens Rettig, Ute Becherer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Both paralogs of the calcium-dependent activator protein for secretion (CAPS) are required for exocytosis of synaptic vesicles (SVs) and large dense core vesicles (LDCVs). Despite approximately 80% sequence identity, CAPS1 and CAPS2 have distinct fun
Externí odkaz:
https://doaj.org/article/5286869c7a7e4edfb1a509880282ac20
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Different families of auxiliary subunits regulate the function and trafficking of native α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors in the central nervous system. While a facilitatory role of auxiliary subunits in ER expor
Externí odkaz:
https://doaj.org/article/830da4f773c64adbb5fd7f04979819a7
Autor:
Ahmed Shaaban, Madhurima Dhara, Walentina Frisch, Ali Harb, Ali H Shaib, Ute Becherer, Dieter Bruns, Ralf Mohrmann
Publikováno v:
eLife, Vol 8 (2019)
SNAP-25 is an essential component of SNARE complexes driving fast Ca2+-dependent exocytosis. Yet, the functional implications of the tandem-like structure of SNAP-25 are unclear. Here, we have investigated the mechanistic role of the acylated “link
Externí odkaz:
https://doaj.org/article/4d6c45f49dac4b799e8442d3e76ed4c0
Autor:
Ali H. Shaib, Angelina Staudt, Ali Harb, Margarete Klose, Ahmed Shaaban, Claudia Schirra, Ralf Mohrmann, Jens Rettig, Ute Becherer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The two paralogs of the calcium-dependent activator protein for secretion (CAPS) are priming factors for synaptic vesicles (SVs) and neuropeptide containing large dense-core vesicles (LDCVs). Yet, it is unclear whether CAPS1 and CAPS2 regulate exocyt
Externí odkaz:
https://doaj.org/article/e4b7907f3a544aca8eac22eb538d917e
Autor:
Ali H. Shaib, Abed Alrahman Chouaib, Rajdeep Chowdhury, Daniel Mihaylov, Chi Zhang, Vanessa Imani, Svilen Veselinov Georgiev, Nikolaos Mougios, Mehar Monga, Sofiia Reshetniak, Tiago Mimoso, Han Chen, Parisa Fatehbasharzad, Dagmar Crzan, Kim-Ann Saal, Nadia Alawar, Janna Eilts, Jinyoung Kang, Luis Alvarez, Claudia Trenkwalder, Brit Mollenhauer, Tiago F. Outeiro, Sarah Köster, Julia Preobraschenski, Ute Becherer, Tobias Moser, Edward S. Boyden, A Radu Aricescu, Markus Sauer, Felipe Opazo, Silvio O. Rizzoli
Fluorescence imaging is one of the most versatile and widely-used tools in biology1. Although techniques to overcome the diffraction barrier were introduced more than two decades ago, and the nominal attainable resolution kept improving2, 3, fluoresc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40997f23ed2c132edc6729dde72197e
https://doi.org/10.1101/2022.08.03.502284
https://doi.org/10.1101/2022.08.03.502284
