Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Uta Wirnitzer"'
Autor:
Anette Sommer, Katrine Wickstroem, Alexander Kristian, Christine Ellingsen, Dominik Mumberg, Heidrun Ellinger-Ziegelbauer, Olav B. Ryan, Jenny Karlsson, Lars Linden, Antje Margret Wengner, Aasmund Larsen, Else-Marie Hagelin, Roger Smeets, Alan Cuthbertson, Urs B. Hagemann, Roger M. Bjerke, Uta Wirnitzer
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 105:410-422
Purpose Fibroblast growth factor receptor 2 (FGFR2) has been previously reported to be overexpressed in several types of cancer, whereas the expression in normal tissue is considered to be moderate to low. Thus, FGFR2 is regarded as an attractive tum
Autor:
Elke Hartmann, Uta Wirnitzer
Publikováno v:
Toxicology Letters. 201:47-57
Infusion studies run during the last 10 years in three rat strains with different flow rates of saline as vehicle were compared as to a potential impact of infused volume on clinicochemical values and histopathology. There were no effects on white an
Autor:
Yoshifumi Uno, Hajime Kojima, Takashi Omori, Raffaella Corvi, Masamistu Honma, Leonard M. Schechtman, Raymond R. Tice, Carol Beevers, Marlies De Boeck, Brian Burlinson, Cheryl A. Hobbs, Sachiko Kitamoto, Andrew R. Kraynak, James McNamee, Yuzuki Nakagawa, Kamala Pant, Ulla Plappert-Helbig, Catherine Priestley, Hironao Takasawa, Kunio Wada, Uta Wirnitzer, Norihide Asano, Patricia A. Escobar, David Lovell, Takeshi Morita, Madoka Nakajima, Yasuo Ohno, Makoto Hayashi
Publikováno v:
Mutation research. Genetic toxicology and environmental mutagenesis.
The in vivo rodent alkaline comet assay (comet assay) is used internationally to investigate the in vivo genotoxic potential of test chemicals. This assay, however, has not previously been formally validated. The Japanese Center for the Validation of
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 609:1-10
Due to the need for in vivo photo-genotoxicity tests, the in vivo photo-comet assay was established in epidermal cells of the SKH-1 mouse. Groups of 10 male SKH-1 mice each were treated once orally with vehicle only, with three fluoroquinolones (25 m
Autor:
Solene Geraudie, Alan Cuthbertson, Dominik Mumberg, Urs B. Hagemann, Olav B. Ryan, Jenny Karlsson, Dessislava Mihaylova, Derek Grant, Bård Indrevoll, Christoph A. Schatz, Alexander Kristian, Christine Ellingsen, Carl Friedrich Nising, Roger M. Bjerke, Uta Wirnitzer
Publikováno v:
Cancer Research. 77:5859-5859
The human epidermal growth factor receptor 2 (HER2) is encoded by the proto-oncogene c-erbB-2 and initiates downstream signaling pathways leading to cell proliferation and tumorigenesis. HER2 is overexpressed in several cancer (Ca) types and is one o
Autor:
Lars Linden, Hanno Wild, Jenny Karlsson, Anette Sommer, Thorsten Poethko, Roger M. Bjerke, Ellen Wang, Uta Wirnitzer, Urs B. Hagemann, Heidrun Ellinger-Ziegelbauer, Alexander Kristian, Alan Cuthbertson, Steffen Sandmann, Bertolt Kreft, Åsmund Larsen
Publikováno v:
Cancer Research. 77:5199-5199
FGFR2 is a transmembrane tyrosine kinase receptor, consisting of three extracellular N-terminal immunoglobulin-like domains which are involved in ligand-binding as well as in receptor dimerization. Ligand-independent activation of FGFR2 signaling eit
Publikováno v:
Toxicologic Pathology. 26:636-645
Most available data on the involvement of p53 in rodent carcinogenesis are based on results of the end point of chemically or virally induced carcinogenesis, i.e., tumors. To investigate the role of altered p53 expression in early stages of rodent he
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 68:e11-e12