Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Uta Schaefer"'
Autor:
S. Lawrence Bailey, Henning Walczak, Erich Greiner, Uta Schaefer, Christopher J. Kemp, Gary Longton, Günther Schütz, Andreea I. Csernok, Oksana Voloshanenko, Anne Grosse-Wilde
Publikováno v:
Journal of Clinical Investigation. 118:100-110
TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in established tumor cell lines but not nontransformed cells. Herein, we demonstrate a role for the apoptosis-inducing TRAIL receptor (TRAIL-R) as a metastasis s
Autor:
Manuela B. Schader, Uta Schaefer, Henning Walczak, Marcel Verheij, Inge Verbrugge, Stefan R. Vink, Esther H.J. Wissink, Jannie Borst
Publikováno v:
Radiotherapy and Oncology. 80:214-222
Background and purpose Resistance to apoptosis is a contributing factor in the response to radiotherapy. Aim of this study was to evaluate whether TRAIL – in a soluble isoleucine zippered form – enhances the cytotoxic effect of irradiation on tum
Autor:
Uta Schaefer
Publikováno v:
Biotechnology Journal. 6:135-137
Publikováno v:
Biotechnology journal. 5(12)
Autor:
Uta Schaefer, Barbara Janssens
Publikováno v:
Biotechnology journal. 5(1)
Autor:
Martin R. Sprick, Menno T. de Bruijn, Maarten W. Nijkamp, B. Florien Westendorp, Ernst J.A. Steller, Onno Kranenburg, Inne H.M. Borel Rinkes, Jan Paul Medema, Niels Smakman, Henning Walczak, Danielle A.E. Raats, Frederik J.H. Hoogwater, Ron C. J. Schackmann, Patrick W. B. Derksen, Winan J. van Houdt, Uta Schaefer, Benjamin L. Emmink
Publikováno v:
Gastroenterology, 138(7), 2357-2367. W.B. Saunders Ltd
Background & Aims Death receptors expressed on tumor cells can prevent metastasis formation by inducing apoptosis, but they also can promote migration and invasion. The determinants of death receptor signaling output are poorly defined. Here we inves
Publikováno v:
Advances in experimental medicine and biology. 647
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo2L, is a member of the TNF superfamily (TNFSF) of cytokines. TRAIL gained much attention during the past decade due to the demonstration of its therapeutic potent
Publikováno v:
Immunology. 127(2)
The members of the tumour necrosis factor (TNF) superfamily of cytokines play important roles in the regulation of various immune-cell functions. Likewise, induction of cell death by apoptosis is indispensable for the normal functioning of the immune