Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Uta M. Demel"'
Autor:
Uta M. Demel, Matthias Wirth, Schayan Yousefian, Le Zhang, Konstandina Isaakidis, Judith Dönig, Marlitt Böger, Nikita Singh, Hazal Köse, Simon Haas, Stefan Müller, Markus Schick, Ulrich Keller
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Aberrant activity of the SUMOylation pathway has been associated with MYC overexpression and poor prognosis in aggressive B-cell lymphoma (BCL) and other malignancies. Recently developed small-molecule inhibitors of SUMOylation (SUMOi) target the het
Externí odkaz:
https://doaj.org/article/0ecbee0d5cf3435ba327c7bfefdcf242
Autor:
Uta M. Demel, Marlitt Böger, Schayan Yousefian, Corinna Grunert, Le Zhang, Paul W. Hotz, Adrian Gottschlich, Hazal Köse, Konstandina Isaakidis, Dominik Vonficht, Florian Grünschläger, Elena Rohleder, Kristina Wagner, Judith Dönig, Veronika Igl, Bernadette Brzezicha, Francis Baumgartner, Stefan Habringer, Jens Löber, Björn Chapuy, Carl Weidinger, Sebastian Kobold, Simon Haas, Antonia B. Busse, Stefan Müller, Matthias Wirth, Markus Schick, Ulrich Keller
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 9 (2022)
Activated SUMOylation is a hallmark of cancer. Starting from a targeted screening for SUMO-regulated immune evasion mechanisms, we identified an evolutionarily conserved function of activated SUMOylation, which attenuated the immunogenicity of tumor
Externí odkaz:
https://doaj.org/article/07797f9821104132ba3cea7f4918f2e9
Autor:
Giorgia Santilli, Stefan Stein, Maren Weisser, Manuel Grez, Joachim Schwäble, Fabien Touzot, Christian Brendel, Uta M. Demel, Adrian J. Thrasher, Ulrich Siler, Stefanie Sujer, Janine Reichenbach, Marieke A.G. Essers, Marina Cavazzana, Linping Chen-Wichmann
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:219-228.e9
Background Defects in phagocytic nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) function cause chronic granulomatous disease (CGD), a primary immunodeficiency characterized by dysfunctional microbicidal activity and chronic inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb5e88125e6d77a05e38306f68ed4e1b
https://doi.org/10.1016/j.jaci.2015.11.028
https://doi.org/10.1016/j.jaci.2015.11.028
Autor:
Uta M. Demel, Marlitt Böger, Schayan Yousefian, Corinna Grunert, Le Zhang, Paul W. Hotz, Adrian Gottschlich, Hazal Köse, Konstandina Isaakidis, Dominik Vonficht, Florian Grünschläger, Elena Rohleder, Kristina Wagner, Judith Dönig, Veronika Igl, Bernadette Brzezicha, Francis Baumgartner, Stefan Habringer, Jens Löber, Björn Chapuy, Carl Weidinger, Sebastian Kobold, Simon Haas, Antonia B. Busse, Stefan Müller, Matthias Wirth, Markus Schick, Ulrich Keller
Publikováno v:
J. Clin. Invest. 132:e152383 (2022)
The Journal of Clinical Investigations
The Journal of Clinical Investigations
Activated SUMOylation is a hallmark of cancer. Starting from a targeted screening for SUMO-regulated immune evasion mechanisms, we identified an evolutionarily conserved function of activated SUMOylation, which attenuated the immunogenicity of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c015a2dcf3f849983bcace47daf02f